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LEUC - LEUD
UniProt: P0A6A6 - P30126
Length: 667
Sequences: 850
Seq/Len: 1.28
I_Prob: 0.82

LEUC - 3-isopropylmalate dehydratase large subunit
Paralog alert: 0.83 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: LEUC
LEUD - 3-isopropylmalate dehydratase small subunit
Paralog alert: 0.14 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: LEUD
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
16_Y 188_A 1.93 0.82
16_Y 185_H 1.52 0.54
52_R 190_A 1.18 0.23
36_T 88_H 1.16 0.21
148_E 112_G 1.13 0.20
160_Q 112_G 1.11 0.18
159_K 171_C 1.09 0.17
411_L 88_H 1.08 0.17
27_I 14_P 1.07 0.16
79_A 178_S 1.03 0.14
33_H 26_I 1.02 0.13
43_G 179_I 1.01 0.12
160_Q 95_D 0.99 0.12
53_Q 193_E 0.97 0.11
443_H 182_T 0.97 0.11
76_G 32_Q 0.96 0.10
48_G 101_V 0.95 0.10
433_E 47_W 0.95 0.10
26_Y 193_E 0.94 0.10
52_R 186_D 0.93 0.09
83_M 49_F 0.92 0.09
318_S 18_A 0.92 0.09
445_V 47_W 0.91 0.08
9_L 56_Q 0.89 0.08
151_H 182_T 0.88 0.07
52_R 193_E 0.88 0.07
226_M 116_N 0.88 0.07
281_A 15_L 0.86 0.07
93_F 192_Y 0.85 0.07
81_I 34_V 0.83 0.06
85_E 34_V 0.82 0.06
210_D 127_A 0.80 0.05
281_A 164_I 0.79 0.05
279_L 93_L 0.78 0.05
149_V 108_D 0.78 0.05
64_N 32_Q 0.78 0.04
56_K 196_Q 0.78 0.04
146_T 88_H 0.78 0.04
350_S 155_A 0.78 0.04
36_T 107_A 0.77 0.04
251_K 195_K 0.77 0.04
66_S 32_Q 0.77 0.04
455_V 195_K 0.77 0.04
423_R 182_T 0.77 0.04
56_K 100_V 0.75 0.04
114_E 79_N 0.75 0.04
240_F 11_L 0.75 0.04
350_S 102_I 0.74 0.04
384_A 166_A 0.74 0.04
38_P 31_L 0.74 0.04
293_N 19_N 0.74 0.04
49_R 182_T 0.73 0.04
462_I 73_I 0.73 0.04
206_E 169_R 0.73 0.04
47_H 180_G 0.73 0.04
73_N 24_A 0.72 0.04
298_I 192_Y 0.72 0.04
82_Q 91_W 0.72 0.04
50_P 190_A 0.72 0.03
251_K 127_A 0.72 0.03
455_V 161_R 0.72 0.03
50_P 188_A 0.72 0.03
9_L 160_Y 0.71 0.03
150_E 91_W 0.71 0.03
38_P 88_H 0.71 0.03
168_I 102_I 0.71 0.03
280_Q 11_L 0.71 0.03
179_T 104_P 0.71 0.03
49_R 179_I 0.71 0.03
39_Q 88_H 0.71 0.03
74_A 32_Q 0.71 0.03
174_A 153_V 0.70 0.03
433_E 91_W 0.70 0.03
184_V 124_L 0.70 0.03
42_D 35_T 0.70 0.03
84_Q 100_V 0.70 0.03
193_S 5_F 0.69 0.03
449_M 111_Y 0.69 0.03
197_T 107_A 0.69 0.03
85_E 14_P 0.69 0.03
82_Q 36_R 0.69 0.03
42_D 116_N 0.69 0.03
60_T 139_N 0.69 0.03
231_G 108_D 0.69 0.03
253_K 161_R 0.69 0.03
300_V 138_A 0.68 0.03
108_V 92_A 0.68 0.03
212_S 137_K 0.68 0.03
64_N 39_F 0.68 0.03
308_A 195_K 0.68 0.03
264_T 156_G 0.68 0.03
438_R 28_K 0.68 0.03
78_M 39_F 0.67 0.03
60_T 140_P 0.67 0.03
24_L 182_T 0.67 0.03
453_A 105_S 0.67 0.03
411_L 31_L 0.67 0.03
155_T 183_L 0.67 0.03
64_N 108_D 0.67 0.03
6_Y 178_S 0.67 0.03
276_V 153_V 0.67 0.03
256_D 125_S 0.67 0.03
299_S 143_H 0.67 0.03
108_V 26_I 0.67 0.03
308_A 131_E 0.66 0.03
341_K 24_A 0.66 0.03
334_L 138_A 0.66 0.03
340_D 178_S 0.66 0.03
276_V 160_Y 0.66 0.03
9_L 166_A 0.66 0.02
360_E 191_A 0.66 0.02
48_G 140_P 0.66 0.02
150_E 179_I 0.65 0.02
42_D 37_T 0.65 0.02
257_D 190_A 0.65 0.02
78_M 33_K 0.65 0.02
2_A 125_S 0.65 0.02
125_V 108_D 0.65 0.02
278_T 127_A 0.65 0.02
229_K 34_V 0.65 0.02
46_A 36_R 0.65 0.02
253_K 127_A 0.65 0.02
223_A 154_K 0.65 0.02
278_T 145_D 0.64 0.02
33_H 92_A 0.64 0.02
282_E 150_A 0.64 0.02
146_T 107_A 0.64 0.02
320_E 181_L 0.64 0.02
150_E 36_R 0.64 0.02
260_A 134_A 0.64 0.02
3_K 65_F 0.64 0.02
324_A 15_L 0.64 0.02
90_C 12_V 0.63 0.02
257_D 194_A 0.63 0.02
244_K 187_D 0.63 0.02
334_L 126_D 0.63 0.02
321_K 46_D 0.63 0.02
455_V 102_I 0.63 0.02
290_W 182_T 0.63 0.02
285_S 134_A 0.63 0.02
285_S 146_V 0.63 0.02
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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