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HEM1 - HEM3
UniProt: P0A6X1 - P06983
Length: 731
Sequences: 557
Seq/Len: 0.77
I_Prob: 0.06

HEM1 - Glutamyl-tRNA reductase
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM1
HEM3 - Porphobilinogen deaminase
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM3
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
91_H 70_L 1.71 0.06
246_I 168_I 1.40 0.03
106_G 18_W 1.37 0.03
209_M 273_R 1.29 0.02
321_A 148_L 1.27 0.02
142_F 197_G 1.26 0.02
286_E 118_A 1.21 0.02
201_L 241_G 1.20 0.01
324_I 54_A 1.19 0.01
53_T 12_Q 1.14 0.01
46_V 10_T 1.13 0.01
192_E 85_V 1.11 0.01
116_Q 56_V 1.10 0.01
185_V 56_V 1.09 0.01
393_T 66_L 1.09 0.01
281_V 89_F 1.08 0.01
7_G 168_I 1.07 0.01
198_A 95_L 1.06 0.01
300_V 128_S 1.06 0.01
13_A 140_R 1.05 0.01
236_I 96_V 1.05 0.01
194_I 185_A 1.05 0.01
112_L 35_V 1.04 0.01
44_G 166_A 1.03 0.01
105_S 217_A 1.03 0.01
162_A 240_G 1.03 0.01
200_H 303_L 1.02 0.01
164_S 16_A 1.01 0.01
187_L 7_R 1.00 0.01
22_S 207_L 1.00 0.01
153_R 18_W 1.00 0.01
213_N 27_L 0.99 0.01
194_I 197_G 0.99 0.01
18_R 67_E 0.98 0.01
192_E 240_G 0.98 0.01
84_L 38_L 0.97 0.01
263_E 168_I 0.97 0.01
22_S 95_L 0.96 0.01
381_A 201_V 0.96 0.01
359_L 87_V 0.96 0.01
321_A 8_I 0.96 0.01
100_L 221_H 0.96 0.01
325_V 187_L 0.95 0.01
363_A 247_G 0.95 0.01
213_N 78_A 0.95 0.01
344_T 248_S 0.95 0.01
255_P 261_A 0.95 0.01
263_E 91_Q 0.94 0.01
363_A 66_L 0.93 0.01
245_I 109_V 0.93 0.01
135_A 201_V 0.93 0.01
387_R 20_A 0.93 0.01
73_L 163_E 0.93 0.01
154_T 252_L 0.93 0.01
187_L 203_I 0.92 0.01
324_I 280_P 0.92 0.01
147_S 20_A 0.92 0.01
252_S 123_S 0.92 0.01
72_W 9_A 0.91 0.01
387_R 36_V 0.91 0.01
47_L 290_L 0.91 0.01
169_A 8_I 0.90 0.01
301_D 130_L 0.90 0.01
94_N 41_M 0.90 0.01
409_N 148_L 0.89 0.01
6_L 188_P 0.89 0.01
294_N 202_G 0.89 0.01
183_V 9_A 0.89 0.01
153_R 110_S 0.89 0.01
84_L 240_G 0.88 0.01
329_T 42_V 0.88 0.01
114_E 43_T 0.88 0.01
213_N 128_S 0.88 0.01
407_R 125_V 0.87 0.01
101_M 291_A 0.87 0.01
249_S 257_I 0.87 0.01
343_E 130_L 0.87 0.01
75_D 219_L 0.86 0.01
409_N 7_R 0.86 0.01
390_H 204_E 0.86 0.01
289_V 108_F 0.86 0.01
35_L 119_L 0.86 0.01
346_R 290_L 0.86 0.01
370_G 286_M 0.86 0.01
192_E 130_L 0.86 0.01
104_A 69_A 0.86 0.01
160_A 264_G 0.86 0.01
13_A 142_D 0.85 0.01
407_R 87_V 0.85 0.01
156_T 298_G 0.85 0.01
383_K 196_V 0.85 0.01
366_A 234_M 0.85 0.01
58_S 128_S 0.85 0.01
358_E 203_I 0.85 0.01
101_M 97_T 0.85 0.01
281_V 240_G 0.85 0.01
8_I 152_V 0.85 0.00
359_L 52_P 0.84 0.00
18_R 61_L 0.84 0.00
381_A 221_H 0.84 0.00
316_A 253_I 0.84 0.00
37_A 188_P 0.84 0.00
301_D 50_D 0.84 0.00
209_M 282_D 0.84 0.00
124_A 221_H 0.84 0.00
97_V 254_D 0.83 0.00
124_A 104_P 0.83 0.00
107_L 250_A 0.83 0.00
51_N 238_L 0.83 0.00
162_A 67_E 0.83 0.00
332_F 90_P 0.83 0.00
217_E 95_L 0.83 0.00
185_V 97_T 0.83 0.00
46_V 93_L 0.83 0.00
307_I 61_L 0.83 0.00
394_K 66_L 0.82 0.00
43_G 201_V 0.82 0.00
59_V 302_I 0.82 0.00
12_T 230_A 0.82 0.00
138_L 206_R 0.82 0.00
298_Y 61_L 0.82 0.00
252_S 23_V 0.82 0.00
293_A 125_V 0.82 0.00
393_T 153_G 0.82 0.00
132_H 272_I 0.82 0.00
309_H 185_A 0.81 0.00
147_S 10_T 0.81 0.00
199_R 10_T 0.81 0.00
279_I 197_G 0.81 0.00
110_L 63_V 0.81 0.00
175_Q 66_L 0.81 0.00
114_E 126_G 0.81 0.00
273_P 224_T 0.81 0.00
209_M 23_V 0.80 0.00
186_L 181_S 0.80 0.00
407_R 164_Y 0.80 0.00
170_C 27_L 0.80 0.00
105_S 134_C 0.80 0.00
330_S 254_D 0.79 0.00
106_G 63_V 0.79 0.00
233_L 125_V 0.79 0.00
69_L 143_L 0.79 0.00
190_A 287_G 0.79 0.00
307_I 130_L 0.79 0.00
312_A 220_N 0.79 0.00
125_F 12_Q 0.79 0.00
1_M 278_G 0.79 0.00
190_A 78_A 0.79 0.00
130_K 144_I 0.79 0.00
69_L 99_C 0.78 0.00
316_A 292_E 0.78 0.00
22_S 70_L 0.78 0.00
329_T 192_S 0.78 0.00
71_R 221_H 0.78 0.00
105_S 152_V 0.78 0.00
326_A 25_D 0.78 0.00
288_E 100_E 0.78 0.00
396_L 292_E 0.78 0.00
35_L 27_L 0.77 0.00
7_G 82_M 0.77 0.00
317_A 66_L 0.77 0.00
238_E 221_H 0.77 0.00
166_A 130_L 0.77 0.00
192_E 235_N 0.77 0.00
118_L 75_A 0.77 0.00
219_A 247_G 0.77 0.00
200_H 67_E 0.77 0.00
20_R 124_I 0.77 0.00
380_L 205_C 0.77 0.00
18_R 240_G 0.77 0.00
340_S 10_T 0.77 0.00
21_V 104_P 0.76 0.00
23_F 158_K 0.76 0.00
209_M 281_Q 0.76 0.00
318_A 128_S 0.76 0.00
130_K 98_I 0.76 0.00
198_A 25_D 0.76 0.00
225_E 275_E 0.76 0.00
197_V 247_G 0.76 0.00
181_S 125_V 0.76 0.00
136_S 247_G 0.76 0.00
318_A 148_L 0.76 0.00
389_I 298_G 0.76 0.00
101_M 89_F 0.76 0.00
248_S 66_L 0.76 0.00
172_L 259_L 0.76 0.00
12_T 287_G 0.75 0.00
37_A 129_S 0.75 0.00
203_E 97_T 0.75 0.00
35_L 294_L 0.75 0.00
8_I 261_A 0.75 0.00
162_A 246_I 0.75 0.00
161_S 166_A 0.75 0.00
213_N 261_A 0.75 0.00
10_H 245_P 0.75 0.00
246_I 14_P 0.75 0.00
246_I 203_I 0.75 0.00
312_A 185_A 0.75 0.00
276_L 249_Y 0.75 0.00
284_D 169_L 0.75 0.00
114_E 169_L 0.75 0.00
268_S 177_L 0.75 0.00
56_Y 297_N 0.75 0.00
84_L 204_E 0.75 0.00
145_S 203_I 0.74 0.00
220_Q 300_R 0.74 0.00
140_R 85_V 0.74 0.00
310_N 66_L 0.74 0.00
418_E 154_T 0.74 0.00
281_V 64_K 0.74 0.00
331_E 166_A 0.74 0.00
226_V 82_M 0.74 0.00
290_G 259_L 0.74 0.00
74_C 261_A 0.74 0.00
142_F 54_A 0.74 0.00
101_M 121_A 0.74 0.00
17_L 272_I 0.74 0.00
56_Y 97_T 0.74 0.00
274_M 99_C 0.74 0.00
351_Q 233_A 0.74 0.00
266_L 189_P 0.74 0.00
12_T 190_E 0.73 0.00
146_F 219_L 0.73 0.00
165_V 193_L 0.73 0.00
115_P 82_M 0.73 0.00
335_W 261_A 0.73 0.00
7_G 69_A 0.73 0.00
192_E 64_K 0.73 0.00
285_V 247_G 0.73 0.00
47_L 14_P 0.73 0.00
314_R 64_K 0.73 0.00
289_V 188_P 0.73 0.00
166_A 67_E 0.73 0.00
253_P 223_E 0.73 0.00
172_L 90_P 0.73 0.00
332_F 23_V 0.73 0.00
150_K 195_A 0.73 0.00
48_S 264_G 0.73 0.00
106_G 20_A 0.73 0.00
80_N 254_D 0.73 0.00
247_I 250_A 0.73 0.00
397_Q 36_V 0.73 0.00
139_E 197_G 0.73 0.00
141_M 200_A 0.73 0.00
34_S 221_H 0.73 0.00
194_I 302_I 0.72 0.00
122_K 254_D 0.72 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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