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PYRD - PYRE
UniProt: P0A7E1 - P0A7E3
Length: 549
Sequences: 315
Seq/Len: 0.67
I_Prob: 0.00

PYRD - Dihydroorotate dehydrogenase (quinone)
Paralog alert: 0.39 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: PYRD
PYRE - Orotate phosphoribosyltransferase
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: APT PYRE
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
99_R 124_D 1.25 0.00
139_N 124_D 1.24 0.00
271_L 178_V 1.22 0.00
317_I 92_D 1.17 0.00
199_N 63_E 1.08 0.00
308_I 78_A 1.07 0.00
146_T 60_S 1.05 0.00
276_T 80_T 1.03 0.00
316_Q 107_E 1.01 0.00
290_L 14_S 1.00 0.00
304_A 39_L 1.00 0.00
315_V 81_T 0.99 0.00
171_I 68_F 0.98 0.00
276_T 50_G 0.97 0.00
169_I 153_S 0.97 0.00
197_I 78_A 0.97 0.00
171_I 12_A 0.97 0.00
305_R 92_D 0.96 0.00
271_L 102_A 0.94 0.00
319_S 118_G 0.93 0.00
309_A 151_L 0.93 0.00
113_M 6_R 0.92 0.00
137_G 119_R 0.92 0.00
334_T 82_A 0.92 0.00
219_A 82_A 0.91 0.00
315_V 107_E 0.91 0.00
210_K 180_S 0.90 0.00
56_N 120_V 0.90 0.00
214_I 176_C 0.89 0.00
245_T 120_V 0.89 0.00
154_D 50_G 0.89 0.00
242_V 143_N 0.89 0.00
159_M 166_A 0.88 0.00
195_T 175_N 0.88 0.00
171_I 122_L 0.87 0.00
284_L 166_A 0.87 0.00
96_D 133_I 0.87 0.00
254_V 45_D 0.87 0.00
228_I 77_I 0.87 0.00
244_A 116_L 0.87 0.00
56_N 113_G 0.87 0.00
290_L 3_P 0.86 0.00
154_D 54_A 0.86 0.00
77_M 145_A 0.86 0.00
287_N 93_L 0.86 0.00
99_R 70_P 0.86 0.00
313_S 124_D 0.85 0.00
92_Q 18_L 0.85 0.00
272_Q 107_E 0.85 0.00
276_T 182_I 0.85 0.00
160_E 10_E 0.85 0.00
328_L 138_E 0.85 0.00
72_D 122_L 0.84 0.00
292_I 147_L 0.84 0.00
112_R 58_V 0.84 0.00
58_L 67_L 0.83 0.00
78_G 59_D 0.83 0.00
70_C 124_D 0.83 0.00
122_N 175_N 0.83 0.00
294_G 26_K 0.82 0.00
219_A 35_F 0.81 0.00
282_L 136_S 0.81 0.00
83_E 106_G 0.81 0.00
334_T 168_Q 0.81 0.00
169_I 60_S 0.81 0.00
139_N 118_G 0.80 0.00
319_S 13_L 0.80 0.00
271_L 43_G 0.80 0.00
154_D 191_L 0.80 0.00
234_L 157_Q 0.80 0.00
84_I 150_V 0.80 0.00
266_L 206_A 0.79 0.00
100_L 48_L 0.79 0.00
305_R 142_A 0.79 0.00
313_S 42_T 0.79 0.00
300_S 120_V 0.79 0.00
317_I 190_Y 0.79 0.00
59_G 82_A 0.79 0.00
164_A 117_Q 0.79 0.00
154_D 201_L 0.78 0.00
97_K 68_F 0.78 0.00
281_R 153_S 0.78 0.00
271_L 179_I 0.77 0.00
140_I 109_G 0.77 0.00
281_R 16_Q 0.77 0.00
121_D 188_I 0.77 0.00
293_I 181_I 0.76 0.00
123_L 26_K 0.76 0.00
87_V 49_L 0.76 0.00
169_I 58_V 0.76 0.00
91_P 106_G 0.76 0.00
75_G 79_T 0.76 0.00
140_I 121_M 0.76 0.00
243_I 189_A 0.76 0.00
332_I 157_Q 0.76 0.00
188_E 51_R 0.76 0.00
84_I 43_G 0.76 0.00
146_T 166_A 0.76 0.00
89_P 63_E 0.75 0.00
281_R 145_A 0.75 0.00
124_V 21_G 0.75 0.00
197_I 95_Y 0.75 0.00
320_G 180_S 0.75 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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