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PFLA - PFLB
UniProt: P0A9N4 - P09373
Length: 1006
Sequences: 689
Seq/Len: 0.70
I_Prob: 0.92

PFLA - Pyruvate formate-lyase 1-activating enzyme
Paralog alert: 0.54 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: NRDG PFLA PFLC PFLE YJJW
PFLB - Formate acetyltransferase 1
Paralog alert: 0.50 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: PFLB PFLD PFLF TDCE
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
66_F 650_T 2.39 0.92
59_E 643_K 1.84 0.67
62_T 570_N 1.70 0.54
70_S 688_G 1.39 0.27
103_C 160_C 1.13 0.11
164_V 195_K 1.11 0.10
66_F 570_N 1.10 0.10
179_D 293_K 1.08 0.09
159_N 25_N 1.06 0.08
103_C 490_Q 1.04 0.08
228_E 459_V 1.01 0.07
205_L 121_G 1.00 0.07
170_V 484_M 0.99 0.06
161_N 301_E 0.98 0.06
175_S 11_A 0.96 0.06
136_D 474_D 0.95 0.05
210_W 522_T 0.94 0.05
103_C 166_L 0.91 0.04
100_I 306_V 0.91 0.04
63_Y 646_V 0.91 0.04
196_K 681_V 0.90 0.04
62_T 650_T 0.90 0.04
227_K 473_Y 0.87 0.04
58_K 293_K 0.87 0.04
28_Q 669_S 0.87 0.04
58_K 93_Q 0.86 0.04
109_F 136_K 0.86 0.04
96_K 224_I 0.86 0.03
214_G 627_G 0.84 0.03
135_N 60_E 0.84 0.03
131_L 714_E 0.84 0.03
91_W 218_I 0.84 0.03
70_S 38_E 0.84 0.03
192_G 21_Q 0.82 0.03
21_I 18_G 0.82 0.03
199_L 319_L 0.81 0.03
139_H 302_A 0.81 0.03
10_F 552_D 0.81 0.03
118_D 25_N 0.81 0.03
123_V 45_A 0.80 0.03
59_E 570_N 0.80 0.03
121_L 713_R 0.80 0.03
136_D 24_V 0.80 0.03
56_L 442_T 0.80 0.03
65_H 692_G 0.79 0.03
103_C 11_A 0.79 0.03
144_G 294_A 0.79 0.03
103_C 367_S 0.79 0.02
220_D 251_N 0.79 0.02
199_L 597_D 0.79 0.02
225_P 522_T 0.79 0.02
77_S 192_Y 0.78 0.02
19_P 272_G 0.78 0.02
218_K 655_L 0.78 0.02
195_E 297_I 0.78 0.02
7_I 587_K 0.78 0.02
93_R 688_G 0.78 0.02
179_D 289_E 0.78 0.02
139_H 74_F 0.77 0.02
202_Y 308_H 0.77 0.02
226_K 136_K 0.77 0.02
177_D 251_N 0.77 0.02
139_H 116_I 0.76 0.02
179_D 19_D 0.76 0.02
159_N 201_F 0.76 0.02
148_H 24_V 0.76 0.02
92_F 500_Y 0.76 0.02
52_T 554_L 0.75 0.02
202_Y 681_V 0.75 0.02
186_E 474_D 0.75 0.02
66_F 696_H 0.75 0.02
96_K 90_I 0.74 0.02
66_F 646_V 0.74 0.02
36_Y 11_A 0.74 0.02
199_L 551_E 0.73 0.02
124_T 301_E 0.73 0.02
57_M 293_K 0.73 0.02
148_H 548_I 0.73 0.02
94_A 238_A 0.73 0.02
198_E 706_L 0.73 0.02
140_Q 93_Q 0.73 0.02
14_G 668_F 0.73 0.02
7_I 47_A 0.73 0.02
155_K 297_I 0.73 0.02
105_D 608_T 0.72 0.02
153_F 26_V 0.72 0.02
32_M 340_G 0.72 0.02
213_M 567_F 0.72 0.02
77_S 230_A 0.72 0.02
117_I 494_A 0.72 0.02
9_S 177_R 0.72 0.02
227_K 253_Q 0.72 0.02
152_E 550_D 0.72 0.02
66_F 550_D 0.72 0.02
56_L 31_Q 0.72 0.02
12_S 25_N 0.72 0.02
175_S 488_A 0.72 0.02
86_E 446_A 0.71 0.02
183_R 49_E 0.71 0.02
123_V 300_Q 0.71 0.02
170_V 239_A 0.71 0.02
229_T 416_A 0.71 0.02
44_D 293_K 0.71 0.02
128_M 730_T 0.71 0.02
155_K 294_A 0.71 0.02
15_T 574_V 0.71 0.02
218_K 152_V 0.71 0.02
45_T 155_P 0.71 0.02
87_F 279_R 0.71 0.02
94_A 160_C 0.71 0.02
175_S 464_E 0.70 0.02
66_F 81_T 0.70 0.01
64_R 34_Y 0.70 0.01
109_F 232_G 0.70 0.01
202_Y 554_L 0.70 0.01
70_S 204_L 0.70 0.01
140_Q 625_R 0.70 0.01
205_L 166_L 0.70 0.01
101_H 232_G 0.70 0.01
207_K 239_A 0.70 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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