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NRFC - NRFD
UniProt: P0AAK7 - P32709
Length: 541
Sequences: 649
Seq/Len: 1.23
I_Prob: 0.93

NRFC - Protein NrfC
Paralog alert: 0.66 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: DMSB HYCB HYDN HYFA NRFC YDHX YDHY YGFS YNFG YSAA
NRFD - Protein NrfD
Paralog alert: 0.70 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: HYBB NRFD
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2vpzBF:CG:BFContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
130_Y 92_S 2.14 0.93
129_Q 76_T 1.76 0.79
124_L 87_H 1.60 0.69
154_F 55_T 1.53 0.63
106_T 67_G 1.35 0.45
147_K 76_T 1.34 0.45
36_R 233_V 1.34 0.44
64_E 313_G 1.19 0.30
93_Q 21_Y 1.14 0.25
130_Y 182_P 1.13 0.25
139_V 74_H 1.12 0.24
150_D 76_T 1.09 0.22
114_A 233_V 1.08 0.21
47_I 178_N 1.08 0.21
129_Q 68_L 1.07 0.20
151_K 176_L 1.06 0.19
139_V 38_L 1.06 0.19
191_Q 270_L 1.05 0.18
191_Q 219_R 1.04 0.18
114_A 278_L 1.04 0.18
185_P 134_V 1.04 0.18
99_P 12_L 1.03 0.18
186_N 273_I 1.03 0.17
129_Q 162_Y 1.01 0.16
195_Q 273_I 1.01 0.16
157_K 294_A 1.01 0.16
106_T 24_L 1.01 0.16
115_S 240_A 1.01 0.16
109_S 80_T 1.00 0.15
103_V 31_L 1.00 0.15
159_N 172_S 0.98 0.14
58_E 310_L 0.98 0.14
210_K 120_L 0.98 0.14
142_I 167_L 0.98 0.14
139_V 173_Y 0.98 0.14
176_A 94_M 0.97 0.14
129_Q 17_P 0.96 0.13
78_G 75_L 0.95 0.13
154_F 23_F 0.95 0.13
47_I 81_F 0.94 0.12
190_S 234_A 0.93 0.12
124_L 268_A 0.93 0.11
98_A 277_L 0.93 0.11
169_V 23_F 0.93 0.11
132_I 81_F 0.92 0.11
87_F 61_P 0.92 0.11
89_R 166_L 0.91 0.11
117_I 273_I 0.91 0.10
138_R 156_A 0.90 0.10
160_L 75_L 0.90 0.10
202_K 51_T 0.90 0.10
130_Y 174_P 0.90 0.10
94_H 68_L 0.90 0.10
37_Y 12_L 0.89 0.10
130_Y 19_A 0.89 0.09
171_A 243_D 0.88 0.09
47_I 233_V 0.88 0.09
179_F 19_A 0.88 0.09
68_R 21_Y 0.88 0.09
55_A 195_A 0.88 0.09
103_V 25_I 0.88 0.09
124_L 83_K 0.88 0.09
71_I 268_A 0.87 0.09
202_K 36_V 0.87 0.09
191_Q 259_W 0.87 0.09
36_R 129_P 0.87 0.09
163_G 264_W 0.86 0.09
190_S 217_V 0.86 0.09
73_R 237_V 0.86 0.09
189_I 179_P 0.86 0.09
96_D 23_F 0.86 0.09
99_P 266_G 0.86 0.08
178_T 293_A 0.86 0.08
65_G 95_S 0.86 0.08
149_A 95_S 0.85 0.08
213_R 80_T 0.85 0.08
91_S 94_M 0.85 0.08
189_I 219_R 0.85 0.08
171_A 265_L 0.84 0.08
126_V 15_D 0.84 0.08
183_D 310_L 0.84 0.08
41_H 308_F 0.84 0.08
184_D 134_V 0.84 0.08
89_R 168_S 0.84 0.08
141_F 156_A 0.84 0.07
66_V 155_L 0.84 0.07
70_T 72_V 0.83 0.07
129_Q 8_H 0.83 0.07
191_Q 214_A 0.83 0.07
154_F 93_V 0.83 0.07
109_S 75_L 0.83 0.07
208_K 73_F 0.83 0.07
150_D 9_F 0.83 0.07
194_R 151_L 0.83 0.07
193_L 81_F 0.83 0.07
137_Y 114_K 0.83 0.07
119_D 61_P 0.82 0.07
140_R 164_G 0.82 0.07
79_E 107_V 0.82 0.07
185_P 120_L 0.82 0.07
38_G 8_H 0.82 0.07
178_T 59_V 0.82 0.07
169_V 22_L 0.81 0.07
129_Q 279_K 0.81 0.07
45_L 222_I 0.80 0.06
147_K 175_F 0.80 0.06
153_D 172_S 0.80 0.06
97_H 43_P 0.80 0.06
47_I 214_A 0.80 0.06
47_I 184_L 0.80 0.06
206_G 229_I 0.80 0.06
132_I 8_H 0.80 0.06
111_R 300_V 0.80 0.06
201_Y 308_F 0.80 0.06
186_N 300_V 0.80 0.06
174_T 18_I 0.79 0.06
99_P 27_I 0.79 0.06
150_D 162_Y 0.79 0.06
103_V 98_V 0.79 0.06
208_K 229_I 0.79 0.06
129_Q 15_D 0.78 0.06
130_Y 169_A 0.78 0.06
117_I 174_P 0.78 0.06
182_L 13_V 0.78 0.06
48_G 94_M 0.78 0.06
102_D 17_P 0.78 0.06
133_A 104_Y 0.78 0.06
192_L 286_S 0.78 0.06
144_P 155_L 0.78 0.06
144_P 18_I 0.77 0.06
122_P 94_M 0.77 0.06
188_E 206_R 0.77 0.06
149_A 80_T 0.77 0.05
185_P 130_K 0.77 0.05
205_L 143_P 0.77 0.05
73_R 163_T 0.77 0.05
59_V 311_Y 0.77 0.05
140_R 25_I 0.77 0.05
142_I 76_T 0.76 0.05
182_L 132_G 0.76 0.05
148_T 104_Y 0.76 0.05
173_P 77_R 0.75 0.05
174_T 236_F 0.75 0.05
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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