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CYSD - CYSN
UniProt: P21156 - P23845
Length: 777
Sequences: 638
Seq/Len: 0.87
I_Prob: 1.00

CYSD - Sulfate adenylyltransferase subunit 2
Paralog alert: 0.08 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: CYSD
CYSN - Sulfate adenylyltransferase subunit 1
Paralog alert: 0.34 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: CYSN EFTU1 EFTU2
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1zunB:AContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
26_E 358_K 3.51 1.00
161_K 319_S 2.58 0.98
48_R 295_F 1.73 0.76
169_H 414_V 1.49 0.56
10_R 306_E 1.43 0.50
26_E 363_K 1.32 0.39
120_K 359_I 1.28 0.35
6_L 306_E 1.26 0.33
54_G 264_A 1.20 0.27
17_I 296_D 1.16 0.24
157_R 359_I 1.15 0.23
78_R 357_I 1.13 0.21
43_M 79_A 1.12 0.21
192_Q 390_L 1.11 0.20
52_Y 299_R 1.09 0.18
269_I 170_M 1.08 0.18
174_Q 363_K 1.08 0.18
291_G 86_Q 1.07 0.17
174_Q 426_N 1.04 0.15
268_I 224_S 1.03 0.15
74_E 385_V 1.03 0.15
52_Y 293_V 1.03 0.15
270_E 14_G 1.02 0.14
75_F 207_A 1.00 0.13
207_P 167_I 1.00 0.13
181_I 56_E 0.99 0.13
270_E 229_L 0.99 0.13
95_G 307_A 0.99 0.12
112_D 208_L 0.97 0.12
99_G 349_L 0.97 0.12
258_V 288_N 0.97 0.11
276_T 63_H 0.97 0.11
167_L 208_L 0.96 0.11
43_M 289_V 0.96 0.11
148_I 280_V 0.95 0.10
153_D 79_A 0.95 0.10
235_P 277_R 0.95 0.10
48_R 307_A 0.94 0.10
194_I 290_A 0.93 0.10
41_S 229_L 0.93 0.10
82_A 246_M 0.93 0.09
246_F 355_Y 0.93 0.09
275_S 136_L 0.92 0.09
237_E 176_S 0.92 0.09
173_G 287_S 0.92 0.09
60_L 138_I 0.91 0.09
95_G 154_I 0.91 0.09
41_S 10_A 0.91 0.09
78_R 59_L 0.91 0.09
194_I 273_E 0.91 0.09
45_H 307_A 0.90 0.08
153_D 111_I 0.90 0.08
67_W 148_T 0.90 0.08
298_R 402_E 0.89 0.08
269_I 185_E 0.89 0.08
63_V 217_S 0.88 0.08
148_I 345_A 0.88 0.08
82_A 366_A 0.88 0.08
148_I 328_D 0.88 0.08
273_L 18_W 0.88 0.07
277_T 213_V 0.88 0.07
298_R 152_S 0.88 0.07
54_G 49_H 0.87 0.07
239_I 274_V 0.87 0.07
114_M 154_I 0.87 0.07
289_Q 208_L 0.87 0.07
78_R 348_P 0.87 0.07
95_G 266_T 0.86 0.07
27_F 50_D 0.85 0.07
278_S 77_D 0.85 0.07
175_I 279_K 0.85 0.07
283_R 143_G 0.85 0.07
127_G 305_G 0.85 0.06
295_L 86_Q 0.85 0.06
276_T 105_E 0.84 0.06
194_I 313_T 0.84 0.06
235_P 182_R 0.84 0.06
275_S 76_L 0.84 0.06
169_H 324_L 0.84 0.06
10_R 324_L 0.84 0.06
275_S 5_L 0.84 0.06
299_Q 418_L 0.83 0.06
6_L 303_F 0.83 0.06
153_D 165_V 0.83 0.06
43_M 155_S 0.83 0.06
24_A 155_S 0.83 0.06
265_L 420_F 0.82 0.06
54_G 277_R 0.82 0.06
223_L 394_G 0.82 0.06
56_L 396_V 0.82 0.06
212_A 286_E 0.82 0.05
248_T 148_T 0.81 0.05
61_L 324_L 0.81 0.05
75_F 79_A 0.81 0.05
194_I 401_D 0.81 0.05
148_I 374_Q 0.81 0.05
177_K 106_K 0.81 0.05
211_A 216_Q 0.81 0.05
210_L 364_T 0.80 0.05
270_E 5_L 0.80 0.05
95_G 44_I 0.80 0.05
63_V 56_E 0.80 0.05
258_V 203_V 0.80 0.05
111_T 148_T 0.80 0.05
36_I 125_A 0.80 0.05
175_I 213_V 0.80 0.05
161_K 67_K 0.80 0.05
132_F 114_T 0.80 0.05
124_N 324_L 0.80 0.05
194_I 307_A 0.80 0.05
19_I 175_Y 0.80 0.05
277_T 269_S 0.80 0.05
202_N 177_E 0.79 0.05
24_A 133_L 0.79 0.05
169_H 26_S 0.79 0.05
275_S 51_T 0.79 0.05
47_A 380_L 0.79 0.05
48_R 154_I 0.79 0.05
29_N 272_V 0.79 0.05
74_E 406_L 0.79 0.05
240_K 425_S 0.79 0.05
73_Y 339_V 0.79 0.05
203_I 423_R 0.79 0.05
24_A 252_Y 0.78 0.05
290_A 407_D 0.78 0.05
85_C 205_L 0.78 0.05
261_N 379_N 0.78 0.05
129_D 148_T 0.78 0.04
131_A 56_E 0.78 0.04
170_N 361_G 0.78 0.04
70_R 159_G 0.78 0.04
16_S 283_S 0.78 0.04
83_Y 176_S 0.78 0.04
179_E 269_S 0.78 0.04
270_E 10_A 0.78 0.04
167_L 119_Q 0.77 0.04
217_L 351_P 0.77 0.04
269_I 330_A 0.77 0.04
18_H 130_T 0.77 0.04
27_F 158_L 0.77 0.04
60_L 227_T 0.77 0.04
54_G 203_V 0.77 0.04
160_P 100_R 0.77 0.04
153_D 214_A 0.77 0.04
25_A 55_Y 0.77 0.04
20_I 358_K 0.77 0.04
63_V 385_V 0.76 0.04
60_L 304_A 0.76 0.04
261_N 337_A 0.76 0.04
73_Y 276_Q 0.76 0.04
208_L 234_T 0.76 0.04
243_M 332_P 0.76 0.04
131_A 426_N 0.76 0.04
89_V 157_L 0.76 0.04
284_V 197_N 0.76 0.04
204_D 362_K 0.76 0.04
216_V 284_G 0.76 0.04
235_P 192_G 0.76 0.04
266_P 16_E 0.76 0.04
151_F 170_M 0.76 0.04
98_M 347_Q 0.76 0.04
258_V 138_I 0.75 0.04
109_K 202_F 0.75 0.04
238_V 227_T 0.75 0.04
49_K 128_A 0.75 0.04
256_G 143_G 0.75 0.04
246_F 260_F 0.75 0.04
298_R 213_V 0.75 0.04
24_A 235_V 0.75 0.04
203_I 378_N 0.75 0.04
56_L 215_S 0.75 0.04
148_I 429_V 0.75 0.04
23_V 426_N 0.75 0.04
202_N 106_K 0.75 0.04
151_F 376_D 0.75 0.04
252_W 365_R 0.75 0.04
82_A 289_V 0.74 0.04
196_Q 110_I 0.74 0.04
176_N 376_D 0.74 0.04
274_V 10_A 0.74 0.04
78_R 408_R 0.74 0.04
176_N 131_C 0.74 0.04
135_A 367_R 0.74 0.04
298_R 229_L 0.74 0.04
284_V 318_I 0.74 0.04
238_V 138_I 0.74 0.04
155_F 420_F 0.74 0.04
213_E 300_E 0.73 0.04
258_V 17_A 0.73 0.04
81_K 189_T 0.73 0.04
268_I 68_R 0.73 0.04
20_I 179_T 0.73 0.03
246_F 111_I 0.73 0.03
6_L 227_T 0.73 0.03
220_D 60_S 0.73 0.03
79_T 229_L 0.73 0.03
120_K 82_V 0.73 0.03
267_E 273_E 0.73 0.03
263_Q 278_V 0.73 0.03
180_S 419_I 0.72 0.03
170_N 417_G 0.72 0.03
298_R 163_L 0.72 0.03
259_E 190_F 0.72 0.03
235_P 273_E 0.72 0.03
287_R 9_I 0.72 0.03
265_L 30_F 0.72 0.03
157_R 282_P 0.72 0.03
29_N 394_G 0.72 0.03
78_R 308_I 0.72 0.03
232_D 138_I 0.72 0.03
239_I 22_Q 0.72 0.03
240_K 240_V 0.72 0.03
109_K 131_C 0.72 0.03
56_L 430_G 0.72 0.03
270_E 22_Q 0.71 0.03
84_G 352_G 0.71 0.03
55_T 138_I 0.71 0.03
238_V 273_E 0.71 0.03
78_R 288_N 0.71 0.03
141_K 377_I 0.71 0.03
226_I 343_W 0.71 0.03
60_L 119_Q 0.71 0.03
275_S 10_A 0.71 0.03
20_I 63_H 0.71 0.03
149_Y 295_F 0.71 0.03
261_N 267_L 0.71 0.03
70_R 161_K 0.71 0.03
242_R 327_A 0.71 0.03
236_G 274_V 0.71 0.03
118_G 44_I 0.71 0.03
93_P 16_E 0.71 0.03
71_E 207_A 0.71 0.03
259_E 63_H 0.71 0.03
82_A 370_G 0.71 0.03
82_A 290_A 0.71 0.03
70_R 348_P 0.71 0.03
94_E 382_Q 0.71 0.03
288_D 260_F 0.71 0.03
82_A 238_Q 0.71 0.03
203_I 79_A 0.71 0.03
113_I 33_C 0.70 0.03
204_D 337_A 0.70 0.03
240_K 241_V 0.70 0.03
122_A 295_F 0.70 0.03
267_E 176_S 0.70 0.03
149_Y 125_A 0.70 0.03
269_I 282_P 0.70 0.03
170_N 360_A 0.70 0.03
94_E 351_P 0.70 0.03
196_Q 433_M 0.70 0.03
48_R 404_L 0.70 0.03
99_G 157_L 0.70 0.03
128_F 287_S 0.70 0.03
212_A 277_R 0.70 0.03
194_I 52_R 0.70 0.03
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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