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XDHA - XDHC
UniProt: Q46799 - Q46801
Length: 911
Sequences: 1544
Seq/Len: 1.72
I_Prob: 0.99

XDHA - Xanthine dehydrogenase molybdenum-binding subunit
Paralog alert: 0.62 [within 20: 0.24] - ratio of genomes with paralogs
Cluster includes: XDHA XDHD YAGR
XDHC - Xanthine dehydrogenase iron-sulfur-binding subunit
Paralog alert: 0.66 [within 20: 0.18] - ratio of genomes with paralogs
Cluster includes: XDHC YAGT
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
2w3sBHDF:AEGCContact Map
1ffvBE:ADContact Map
1n62BE:ADContact Map
3hrdAE:BF:DHContact Map
1rm6AD:CFContact Map
1t3qBE:ADContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
680_M 139_L 2.35 0.99
9_V 96_A 1.56 0.82
688_Q 128_I 1.44 0.74
9_V 111_I 1.41 0.71
683_M 135_L 1.37 0.68
5_A 96_A 1.34 0.65
646_H 147_M 1.13 0.43
267_R 43_G 1.12 0.42
643_G 143_T 1.10 0.40
18_D 105_F 1.07 0.36
123_Q 13_I 0.99 0.28
643_G 144_G 0.99 0.28
683_M 149_V 0.97 0.26
10_T 90_H 0.94 0.23
642_E 147_M 0.91 0.21
13_A 41_K 0.91 0.20
9_V 88_L 0.90 0.20
262_K 34_E 0.89 0.19
20_V 36_G 0.89 0.19
50_L 100_A 0.88 0.19
575_D 75_E 0.86 0.17
296_G 55_L 0.85 0.16
10_T 83_A 0.84 0.15
113_K 25_G 0.83 0.15
222_P 63_S 0.82 0.14
676_L 46_V 0.81 0.14
6_I 88_L 0.80 0.13
115_A 135_L 0.79 0.12
232_F 101_V 0.74 0.10
675_L 22_A 0.74 0.10
683_M 110_L 0.73 0.09
645_V 154_D 0.73 0.09
289_N 76_I 0.73 0.09
107_D 79_L 0.73 0.09
294_L 35_Q 0.72 0.09
9_V 92_Q 0.72 0.09
215_V 105_F 0.72 0.09
712_P 46_V 0.70 0.08
639_L 99_G 0.70 0.08
534_L 31_L 0.70 0.08
371_A 152_V 0.70 0.08
238_G 102_Q 0.70 0.08
40_V 97_K 0.68 0.07
739_P 82_E 0.68 0.07
56_I 130_E 0.68 0.07
279_A 41_K 0.68 0.07
405_E 130_E 0.67 0.07
655_W 62_D 0.67 0.07
43_N 152_V 0.67 0.07
651_M 143_T 0.66 0.06
530_A 91_V 0.66 0.06
647_G 102_Q 0.66 0.06
266_S 105_F 0.66 0.06
10_T 111_I 0.65 0.06
88_L 28_L 0.65 0.06
742_L 20_L 0.65 0.06
160_Q 75_E 0.65 0.06
294_L 127_T 0.65 0.06
188_T 39_S 0.65 0.06
577_A 54_V 0.65 0.06
236_G 74_K 0.64 0.06
306_G 144_G 0.64 0.06
167_D 117_M 0.64 0.06
350_R 102_Q 0.64 0.06
593_E 76_I 0.64 0.06
109_L 30_E 0.64 0.06
41_S 57_D 0.64 0.05
614_V 108_P 0.63 0.05
475_G 102_Q 0.63 0.05
14_R 38_L 0.63 0.05
653_I 76_I 0.63 0.05
4_D 99_G 0.62 0.05
654_G 144_G 0.62 0.05
268_E 46_V 0.62 0.05
109_L 133_R 0.62 0.05
434_V 40_V 0.62 0.05
133_A 129_T 0.62 0.05
54_L 16_M 0.62 0.05
705_H 112_M 0.62 0.05
15_Y 110_L 0.62 0.05
97_G 100_A 0.61 0.05
682_T 136_A 0.61 0.05
474_I 147_M 0.61 0.05
21_M 13_I 0.61 0.05
650_G 143_T 0.61 0.05
683_M 152_V 0.61 0.05
224_S 150_N 0.61 0.05
170_V 125_P 0.60 0.05
676_L 48_E 0.60 0.04
700_Q 105_F 0.60 0.04
684_P 133_R 0.60 0.04
16_T 65_L 0.60 0.04
127_V 105_F 0.60 0.04
395_G 66_Y 0.60 0.04
112_E 48_E 0.60 0.04
92_H 115_T 0.60 0.04
184_M 139_L 0.60 0.04
373_G 22_A 0.60 0.04
656_A 32_L 0.60 0.04
86_R 100_A 0.60 0.04
659_E 141_R 0.60 0.04
688_Q 111_I 0.60 0.04
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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