GREMLIN.BAKERLAB.org
Powered by OPENSEQ.org
XDHB - XDHC
UniProt: Q46800 - Q46801
Length: 451
Sequences: 1493
Seq/Len: 3.45
I_Prob: 1.00

XDHB - Xanthine dehydrogenase FAD-binding subunit
Paralog alert: 0.56 [within 20: 0.15] - ratio of genomes with paralogs
Cluster includes: XDHB YAGS YGFM
XDHC - Xanthine dehydrogenase iron-sulfur-binding subunit
Paralog alert: 0.66 [within 20: 0.18] - ratio of genomes with paralogs
Cluster includes: XDHC YAGT
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
3hrdCG:DHContact Map
1ffvCF:ADContact Map
1t3qCF:ADContact Map
1n62CF:ADContact Map
1rm6BE:CFContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
79_Q 59_T 2.57 1.00
36_L 67_L 1.88 0.98
29_L 70_W 1.75 0.96
102_G 62_D 1.49 0.90
108_V 62_D 1.44 0.88
7_Y 69_A 1.38 0.85
40_H 27_P 1.25 0.78
104_Q 53_T 1.18 0.72
76_T 59_T 1.12 0.66
9_R 72_E 1.12 0.66
104_Q 113_A 1.05 0.58
53_H 70_W 1.00 0.52
33_T 47_G 0.99 0.51
108_V 66_Y 0.98 0.49
82_E 120_K 0.94 0.44
78_T 59_T 0.91 0.41
34_D 48_E 0.90 0.40
33_T 65_L 0.90 0.40
98_T 133_R 0.87 0.36
51_D 70_W 0.84 0.32
54_N 74_K 0.83 0.32
40_H 45_C 0.81 0.29
106_R 105_F 0.81 0.29
207_N 76_I 0.80 0.28
40_H 48_E 0.79 0.27
112_G 11_C 0.79 0.27
169_F 56_V 0.79 0.27
114_N 41_K 0.78 0.26
171_F 57_D 0.78 0.26
41_H 46_V 0.77 0.25
213_L 105_F 0.74 0.22
33_T 41_K 0.73 0.21
40_H 46_V 0.72 0.20
185_K 62_D 0.69 0.17
40_H 65_L 0.69 0.17
105_I 62_D 0.69 0.17
166_L 21_H 0.68 0.17
251_V 135_L 0.68 0.17
112_G 105_F 0.67 0.16
54_N 72_E 0.67 0.16
216_A 69_A 0.66 0.15
101_A 138_N 0.65 0.14
152_H 27_P 0.65 0.14
40_H 47_G 0.65 0.14
168_A 63_S 0.64 0.14
194_I 48_E 0.64 0.14
241_L 93_Q 0.63 0.13
4_F 23_A 0.62 0.12
34_D 101_V 0.62 0.12
249_E 75_E 0.62 0.12
195_S 27_P 0.62 0.12
14_A 75_E 0.62 0.12
39_L 100_A 0.61 0.12
37_I 42_Q 0.61 0.12
102_G 48_E 0.61 0.12
125_A 27_P 0.61 0.11
37_I 65_L 0.60 0.11
108_V 61_I 0.60 0.11
40_H 67_L 0.60 0.11
127_P 113_A 0.60 0.11
218_G 139_L 0.60 0.11
192_M 110_L 0.59 0.10
193_D 27_P 0.59 0.10
173_P 57_D 0.59 0.10
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

Page generated in 0.032 seconds.