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CVPA - Colicin V production protein
UniProt: P08550 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10169
Length: 162 (157)
Sequences: 665
Seq/Len: 4.24

CVPA
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
15_S 108_R 3.889 1.00
40_V 69_L 2.898 1.00
33_T 77_G 2.332 1.00
48_L 69_L 2.278 1.00
12_I 106_A 2.159 1.00
85_G 97_D 2.052 1.00
34_W 37_A 1.777 1.00
3_W 7_A 1.687 0.99
16_S 102_V 1.644 0.99
45_Y 66_I 1.624 0.99
16_S 106_A 1.595 0.99
4_I 8_I 1.576 0.99
97_D 131_D 1.548 0.98
124_T 127_S 1.533 0.98
135_S 138_I 1.516 0.98
52_F 68_V 1.515 0.98
29_L 108_R 1.503 0.98
15_S 34_W 1.389 0.96
27_E 104_F 1.385 0.96
24_F 28_A 1.372 0.96
48_L 65_A 1.366 0.96
40_V 73_T 1.362 0.96
118_F 145_I 1.358 0.95
80_V 87_L 1.335 0.95
22_R 108_R 1.333 0.95
51_W 79_I 1.296 0.94
24_F 81_N 1.292 0.94
34_W 132_W 1.29 0.94
22_R 109_G 1.289 0.93
72_A 76_V 1.267 0.93
19_S 81_N 1.253 0.92
64_I 72_A 1.239 0.92
19_S 24_F 1.235 0.91
91_T 97_D 1.213 0.90
114_A 135_S 1.21 0.90
114_A 118_F 1.203 0.90
84_I 88_V 1.201 0.90
24_F 76_V 1.193 0.89
15_S 105_G 1.189 0.89
124_T 132_W 1.168 0.88
38_F 70_F 1.156 0.87
53_T 68_V 1.155 0.87
99_V 135_S 1.152 0.87
130_E 134_K 1.146 0.87
44_Y 69_L 1.143 0.87
34_W 108_R 1.14 0.86
6_Y 102_V 1.125 0.85
17_L 21_I 1.121 0.85
99_V 122_S 1.114 0.85
78_A 108_R 1.11 0.84
86_Q 90_K 1.109 0.84
29_L 84_I 1.108 0.84
26_R 81_N 1.106 0.84
29_L 81_N 1.103 0.84
105_G 109_G 1.102 0.84
18_V 108_R 1.099 0.84
59_L 129_S 1.09 0.83
41_A 65_A 1.082 0.82
89_E 93_L 1.082 0.82
77_G 92_G 1.076 0.82
22_R 27_E 1.075 0.82
34_W 74_L 1.069 0.81
45_Y 62_N 1.065 0.81
8_I 69_L 1.061 0.81
38_F 41_A 1.053 0.80
34_W 109_G 1.049 0.79
2_V 6_Y 1.048 0.79
142_S 145_I 1.039 0.79
49_S 62_N 1.03 0.78
73_T 85_G 1.028 0.78
112_I 120_L 1.024 0.77
35_G 143_F 1.021 0.77
65_A 81_N 1.019 0.77
10_A 107_L 1.018 0.77
19_S 38_F 1.015 0.76
56_E 157_S 1.01 0.76
11_V 82_F 1.01 0.76
18_V 34_W 1.003 0.75
108_R 145_I 1.001 0.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3vm7A10.333340.945Contact Map0
3j01B10.617330.949Contact Map0.1
3j3bA10.32722.50.951Contact Map0.137
2ksfA10.46912.20.952Contact Map0.098
2rlwA10.104920.953Contact Map0.013
4gzkA10.3211.80.954Contact Map0.382
3hzqA10.51.50.956Contact Map0.18
4hw9A70.93211.50.957Contact Map0.115
3udcA70.7161.40.957Contact Map0.08
3mp7B10.13581.20.958Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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