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ACP - Acyl carrier protein
UniProt: P0A6A8 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG50003
Length: 78 (77)
Sequences: 1746
Seq/Len: 22.68

ACP
Paralog alert: 0.32 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
7_R 50_E 4.011 1.00
67_Q 71_D 3.569 1.00
28_S 31_E 3.011 1.00
4_I 74_N 2.503 1.00
64_T 68_A 2.387 1.00
29_F 69_A 2.352 1.00
13_G 20_Q 1.996 1.00
25_N 67_Q 1.979 1.00
10_K 20_Q 1.742 1.00
63_I 69_A 1.643 1.00
68_A 71_D 1.633 1.00
8_V 47_L 1.627 1.00
5_E 9_K 1.619 1.00
71_D 74_N 1.578 1.00
19_K 22_E 1.502 1.00
3_T 6_E 1.485 1.00
24_T 27_A 1.462 1.00
5_E 25_N 1.443 1.00
26_N 67_Q 1.433 1.00
13_G 23_V 1.426 1.00
9_K 20_Q 1.407 0.99
46_A 49_E 1.39 0.99
5_E 70_I 1.334 0.99
6_E 10_K 1.323 0.99
41_V 45_M 1.321 0.99
23_V 27_A 1.32 0.99
41_V 57_D 1.308 0.99
59_E 76_H 1.305 0.99
16_L 35_A 1.226 0.98
9_K 13_G 1.203 0.98
25_N 70_I 1.174 0.98
59_E 72_Y 1.15 0.97
8_V 70_I 1.123 0.97
71_D 75_G 1.062 0.95
23_V 66_V 1.057 0.95
13_G 27_A 1.032 0.94
29_F 40_T 1.025 0.93
15_Q 46_A 1.006 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2l9fA10.987299.70.125Contact Map0.822
2kciA10.987299.50.222Contact Map0.342
2lkiA1199.50.231Contact Map0.644
1dv5A10.974499.50.255Contact Map0.452
2cgqA10.987299.40.263Contact Map0.665
2amwA10.987299.40.269Contact Map0.666
2kw2A1199.40.273Contact Map0.55
3ce7A10.987299.40.275Contact Map0.699
4dxeH6199.40.282Contact Map0.882
4h2wC20.987299.40.289Contact Map0.689

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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