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CH10 - 10 kDa chaperonin
UniProt: P0A6F9 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10600
Length: 97 (96)
Sequences: 1640
Seq/Len: 17.08

CH10
Paralog alert: 0.08 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
13_K 81_E 4.552 1.00
13_K 39_E 4.431 1.00
10_V 91_I 3.373 1.00
77_K 82_E 2.801 1.00
49_L 53_E 2.725 1.00
48_I 54_V 2.653 1.00
59_V 91_I 2.442 1.00
37_R 64_I 2.293 1.00
14_R 67_F 1.941 1.00
4_R 96_E 1.918 1.00
3_I 93_A 1.895 1.00
38_G 67_F 1.784 1.00
41_L 83_V 1.759 1.00
70_G 73_V 1.709 1.00
42_A 61_V 1.577 1.00
49_L 55_K 1.569 1.00
60_K 63_D 1.549 1.00
19_T 32_A 1.527 1.00
58_D 88_E 1.477 1.00
57_L 88_E 1.474 1.00
39_E 61_V 1.451 1.00
20_K 26_V 1.439 1.00
15_K 39_E 1.381 0.99
45_N 58_D 1.356 0.99
13_K 83_V 1.345 0.99
15_K 64_I 1.332 0.99
39_E 64_I 1.32 0.99
43_V 57_L 1.305 0.99
39_E 62_G 1.264 0.99
75_S 82_E 1.26 0.99
71_Y 87_S 1.258 0.99
36_T 74_K 1.228 0.98
65_V 91_I 1.185 0.98
11_I 85_I 1.168 0.97
12_V 86_M 1.164 0.97
47_R 89_S 1.126 0.97
8_D 87_S 1.11 0.96
29_G 32_A 1.092 0.96
3_I 11_I 1.079 0.95
4_R 94_I 1.073 0.95
67_F 84_L 1.035 0.94
38_G 86_M 1.029 0.94
32_A 75_S 1.029 0.94
12_V 38_G 1.024 0.93
68_N 92_L 1.009 0.93
36_T 69_D 1.002 0.92
54_V 58_D 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3nx6A10.97941000.032Contact Map0.638
1we3O70.97941000.035Contact Map0.809
1pcqO711000.045Contact Map0.657
1p3hA140.98971000.047Contact Map0.883
1g31A70.86699.90.238Contact Map0.538
1yb5A20.845435.40.902Contact Map0.488
4dupA20.8247300.906Contact Map0.635
2j8zA10.835129.10.906Contact Map0.502
4ilkA20.896928.40.907Contact Map0.524
4dvjA20.845427.70.907Contact Map0.685

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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