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CLPS - ATP-dependent Clp protease adapter protein ClpS
UniProt: P0A8Q6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14241
Length: 106 (94)
Sequences: 513
Seq/Len: 5.46

CLPS
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
53_Y 61_L 3.371 1.00
85_V 103_L 3.239 1.00
53_Y 57_R 3.151 1.00
61_L 71_A 2.864 1.00
64_A 68_Q 2.388 1.00
50_F 91_Y 2.288 1.00
29_K 72_I 2.16 1.00
39_P 97_H 2.125 1.00
48_Q 55_V 2.018 1.00
15_E 20_D 1.987 1.00
33_V 102_T 1.965 1.00
31_I 70_K 1.891 1.00
79_E 82_E 1.886 1.00
29_K 106_A 1.87 1.00
64_A 71_A 1.858 1.00
89_N 100_L 1.71 1.00
32_L 103_L 1.622 0.99
85_V 102_T 1.61 0.99
54_D 57_R 1.479 0.99
77_T 80_V 1.329 0.97
23_K 65_V 1.328 0.97
32_L 78_A 1.284 0.96
88_V 101_C 1.284 0.96
79_E 83_T 1.25 0.95
45_D 91_Y 1.23 0.94
91_Y 95_N 1.225 0.94
50_F 87_M 1.225 0.94
17_K 72_I 1.201 0.93
26_S 105_K 1.143 0.91
31_I 72_I 1.086 0.88
40_M 62_M 1.078 0.87
39_P 100_L 1.073 0.87
86_A 94_E 1.069 0.87
31_I 71_A 1.063 0.86
33_V 78_A 1.047 0.85
56_E 73_C 1.031 0.84
91_Y 96_E 1.022 0.83
32_L 99_L 1.012 0.82
22_L 94_E 1.004 0.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2w9rA111000.23Contact Map0.727
3dnjA20.80191000.28Contact Map0.755
3o1fA10.76421000.307Contact Map0.83
3tqqA10.575518.10.933Contact Map0.113
2blnA20.556613.60.937Contact Map0.109
3ewtE10.226412.60.938Contact Map0.813
1fmtA20.584911.90.939Contact Map0.125
2rm4A10.528310.30.94Contact Map0
4iqfA40.59438.60.942Contact Map0.135
2bw0A10.76428.50.942Contact Map0.098

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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