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BAME - Outer membrane protein assembly factor BamE
UniProt: P0A937 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10952
Length: 113 (111)
Sequences: 352
Seq/Len: 3.17

BAME
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
93_L 101_L 3.112 1.00
52_Q 99_G 3.042 1.00
73_W 95_F 1.99 1.00
45_K 58_A 1.93 1.00
28_Y 62_P 1.889 0.99
59_L 91_L 1.786 0.99
72_T 94_T 1.754 0.99
39_T 77_F 1.585 0.97
33_N 77_F 1.536 0.97
54_Q 57_Y 1.518 0.96
66_D 69_G 1.479 0.96
48_V 104_I 1.419 0.94
46_I 53_Q 1.383 0.93
69_G 72_T 1.377 0.93
12_V 15_M 1.37 0.93
16_L 19_G 1.356 0.92
27_V 67_P 1.347 0.92
56_A 61_T 1.297 0.90
94_T 105_D 1.269 0.88
45_K 57_Y 1.264 0.88
44_S 108_P 1.248 0.87
91_L 104_I 1.248 0.87
1_M 4_K 1.242 0.87
29_R 32_I 1.239 0.87
54_Q 73_W 1.23 0.86
93_L 104_I 1.224 0.86
38_L 42_D 1.219 0.86
46_I 107_K 1.198 0.84
50_M 71_N 1.196 0.84
46_I 58_A 1.196 0.84
70_T 76_V 1.194 0.84
81_P 84_E 1.182 0.83
15_M 38_L 1.155 0.81
43_V 106_N 1.15 0.81
31_D 79_Q 1.145 0.80
71_N 103_N 1.135 0.80
85_G 96_N 1.124 0.79
94_T 103_N 1.11 0.77
21_S 51_T 1.101 0.77
29_R 84_E 1.096 0.76
59_L 66_D 1.094 0.76
39_T 44_S 1.086 0.75
33_N 84_E 1.077 0.74
52_Q 111_S 1.076 0.74
57_Y 77_F 1.073 0.74
42_D 90_T 1.065 0.73
61_T 68_F 1.063 0.73
21_S 73_W 1.062 0.73
45_K 104_I 1.054 0.72
39_T 48_V 1.05 0.72
67_P 79_Q 1.047 0.71
69_G 74_F 1.046 0.71
63_L 101_L 1.044 0.71
40_A 44_S 1.042 0.71
108_P 111_S 1.04 0.71
71_N 96_N 1.034 0.70
100_V 105_D 1.031 0.70
38_L 43_V 1.022 0.69
2_R 5_T 1.022 0.69
43_V 91_L 1.013 0.68
37_Y 53_Q 1.001 0.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2pxgA10.81421000.388Contact Map0.316
2km7A10.831999.90.44Contact Map0.371
2yh9A30.70899.90.505Contact Map0.541
4dm5A40.761199.80.58Contact Map0.418
3d4eA10.902796.60.843Contact Map0.374
3gmvX10.619596.20.851Contact Map0.465
3gmxB20.646960.853Contact Map0.529
3n4iB10.654995.90.854Contact Map0.501
3zbiC140.424880.60.898Contact Map0.134
1msiA10.575246.90.919Contact Map0.168

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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