GREMLIN.BAKERLAB.org
Powered by OPENSEQ.org
RIMI - Ribosomal-protein-alanine acetyltransferase
UniProt: P0A944 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10850
Length: 148 (145)
Sequences: 13758
Seq/Len: 94.88

RIMI
Paralog alert: 0.88 [within 20: 0.22] - ratio of genomes with paralogs
Cluster includes: ATDA PHNO RIMI RIMJ RIML YAFP YEDL YHHY YIAC YJAB YJGM YNCA YPEA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
5_S 46_T 3.414 1.00
5_S 11_D 2.639 1.00
21_R 72_D 2.624 1.00
82_R 118_L 2.52 1.00
89_I 120_F 2.467 1.00
55_A 88_L 2.295 1.00
45_L 80_L 2.222 1.00
82_R 117_S 2.219 1.00
87_H 90_D 2.187 1.00
112_I 116_E 2.139 1.00
89_I 144_L 2.107 1.00
52_A 75_Y 2.1 1.00
116_E 122_E 1.963 1.00
43_F 87_H 1.945 1.00
44_Q 51_M 1.876 1.00
99_T 143_A 1.86 1.00
86_E 118_L 1.791 1.00
122_E 125_I 1.746 1.00
89_I 100_L 1.746 1.00
47_Q 52_A 1.733 1.00
7_L 15_A 1.715 1.00
85_L 118_L 1.713 1.00
113_A 116_E 1.697 1.00
75_Y 78_Q 1.674 1.00
14_A 17_H 1.638 1.00
91_E 95_R 1.637 1.00
91_E 94_K 1.635 1.00
53_A 71_V 1.586 1.00
102_L 115_Y 1.583 1.00
47_Q 75_Y 1.549 1.00
13_P 29_E 1.533 1.00
87_H 91_E 1.518 1.00
82_R 86_E 1.494 1.00
122_E 140_I 1.472 1.00
57_T 88_L 1.469 1.00
123_A 143_A 1.466 1.00
14_A 51_M 1.422 1.00
47_Q 78_Q 1.4 0.99
104_V 108_N 1.397 0.99
125_I 138_D 1.387 0.99
112_I 122_E 1.381 0.99
50_K 72_D 1.373 0.99
109_A 113_A 1.364 0.99
50_K 74_D 1.28 0.99
46_T 49_G 1.272 0.99
9_T 33_A 1.271 0.99
64_A 92_L 1.263 0.99
106_A 138_D 1.263 0.99
76_Q 110_A 1.226 0.98
3_T 46_T 1.2 0.98
17_H 21_R 1.195 0.98
111_A 115_Y 1.19 0.98
21_R 73_P 1.164 0.97
106_A 125_I 1.153 0.97
42_N 56_I 1.148 0.97
17_H 72_D 1.14 0.97
46_T 51_M 1.128 0.97
71_V 80_L 1.128 0.97
14_A 18_I 1.125 0.97
92_L 100_L 1.114 0.96
7_L 42_N 1.11 0.96
107_S 137_E 1.108 0.96
29_E 33_A 1.108 0.96
90_D 94_K 1.106 0.96
57_T 92_L 1.098 0.96
85_L 120_F 1.077 0.95
43_F 91_E 1.076 0.95
79_G 82_R 1.065 0.95
72_D 75_Y 1.065 0.95
55_A 84_L 1.057 0.95
22_A 70_A 1.022 0.93
109_A 112_I 1.019 0.93
14_A 50_K 1.015 0.93
83_A 87_H 1.006 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2cntA4199.90.173Contact Map0.761
3dr6A30.993299.90.188Contact Map0.853
2j8mA20.993299.90.195Contact Map0.742
2ob0A30.986599.90.2Contact Map0.801
4kvxA20.97399.90.221Contact Map0.743
2x7bA10.966299.90.224Contact Map0.812
2reeA2199.90.227Contact Map0.774
3kkwA10.986599.90.227Contact Map0.687
3g8wA40.979799.90.229Contact Map0.825
4l8aA10.986599.90.229Contact Map0.698

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0192 seconds.