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CSPD - Cold shock-like protein CspD
UniProt: P0A968 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11111
Length: 74 (67)
Sequences: 2991
Seq/Len: 44.64

CSPD
Paralog alert: 0.78 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: CSPA CSPB CSPC CSPD CSPE CSPF CSPG CSPH CSPI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
29_A 64_I 3.873 1.00
53_H 62_S 3.845 1.00
51_D 63_V 2.771 1.00
46_Q 66_P 2.412 1.00
5_T 47_S 2.282 1.00
54_Q 59_N 2.227 1.00
21_E 47_S 2.129 1.00
11_N 43_K 2.057 1.00
49_Q 65_V 2.046 1.00
49_Q 67_V 2.038 1.00
3_K 49_Q 1.964 1.00
35_Q 63_V 1.848 1.00
3_K 47_S 1.832 1.00
33_T 62_S 1.757 1.00
20_P 50_F 1.645 1.00
55_G 60_H 1.616 1.00
20_P 24_G 1.598 1.00
61_A 64_I 1.58 1.00
2_E 20_P 1.524 1.00
29_A 42_L 1.505 1.00
20_P 23_G 1.496 1.00
35_Q 65_V 1.449 1.00
47_S 67_V 1.374 0.99
11_N 41_T 1.309 0.99
9_F 31_Y 1.285 0.99
31_Y 34_I 1.27 0.99
20_P 25_E 1.268 0.99
11_N 39_Y 1.238 0.98
43_K 46_Q 1.233 0.98
5_T 19_C 1.208 0.98
3_K 21_E 1.173 0.98
31_Y 40_R 1.151 0.97
2_E 22_G 1.092 0.96
36_M 66_P 1.079 0.95
33_T 53_H 1.061 0.95
52_V 59_N 1.057 0.95
25_E 59_N 1.038 0.94
27_I 52_V 1.015 0.93
34_I 40_R 1.012 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3camA20.905499.90.141Contact Map0.862
3i2zB20.905499.90.162Contact Map0.906
1c9oA20.891999.90.164Contact Map0.842
2lxjA10.891999.90.164Contact Map0.535
3a0jA20.959599.90.167Contact Map0.806
1g6pA10.891999.90.173Contact Map0.477
2lssA10.905499.80.176Contact Map0.576
3uljA20.986599.80.179Contact Map0.789
3ts2A2199.80.182Contact Map0.783
1h95A10.918999.80.184Contact Map0.548

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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