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CSPF - Cold shock-like protein CspF
UniProt: P0A976 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12205
Length: 70 (67)
Sequences: 2960
Seq/Len: 44.18

CSPF
Paralog alert: 0.78 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: CSPA CSPB CSPC CSPD CSPE CSPF CSPG CSPH CSPI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
56_I 65_A 3.962 1.00
32_L 67_V 3.892 1.00
54_C 66_N 2.83 1.00
49_L 69_L 2.372 1.00
8_I 50_R 2.347 1.00
24_S 50_R 2.187 1.00
14_G 46_T 2.138 1.00
52_E 68_Y 2.111 1.00
6_T 52_E 2.079 1.00
38_N 66_N 1.905 1.00
36_A 65_A 1.806 1.00
57_N 62_P 1.783 1.00
6_T 50_R 1.759 1.00
23_P 53_F 1.703 1.00
58_G 63_S 1.692 1.00
23_P 26_G 1.643 1.00
52_E 70_S 1.607 1.00
64_A 67_V 1.565 1.00
23_P 27_R 1.496 1.00
32_L 45_I 1.467 1.00
38_N 68_Y 1.36 0.99
55_R 62_P 1.3 0.99
6_T 24_S 1.289 0.99
14_G 44_E 1.284 0.99
12_F 34_V 1.28 0.99
34_V 37_L 1.267 0.99
28_I 62_P 1.261 0.99
46_T 49_L 1.222 0.98
39_L 69_L 1.22 0.98
14_G 42_A 1.191 0.98
5_M 23_P 1.188 0.98
8_I 22_T 1.171 0.98
50_R 70_S 1.103 0.96
34_V 43_E 1.096 0.96
30_V 55_R 1.045 0.94
58_G 61_G 1.043 0.94
37_L 43_E 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2lssA1199.90.106Contact Map0.607
3camA20.957199.90.121Contact Map0.87
3i2zB20.985799.90.123Contact Map0.923
1h95A1199.90.134Contact Map0.549
1c9oA20.942999.80.141Contact Map0.863
1g6pA10.928699.80.146Contact Map0.511
2lxjA10.942999.80.149Contact Map0.545
2kcmA10.928699.80.154Contact Map0.506
3a0jA20.942999.80.164Contact Map0.828
3uljA20.971499.80.164Contact Map0.809

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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