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CSPG - Cold shock-like protein CspG
UniProt: P0A978 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14243
Length: 70 (67)
Sequences: 2982
Seq/Len: 44.51

CSPG
Paralog alert: 0.78 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: CSPA CSPB CSPC CSPD CSPE CSPF CSPG CSPH CSPI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
32_V 67_V 3.883 1.00
56_E 65_A 3.858 1.00
54_S 66_N 2.876 1.00
49_Q 69_T 2.375 1.00
8_L 50_K 2.242 1.00
24_D 50_K 2.177 1.00
52_E 68_V 2.176 1.00
14_A 46_N 2.123 1.00
6_T 52_E 2.022 1.00
6_T 50_K 1.814 1.00
38_Q 66_N 1.794 1.00
36_A 65_A 1.739 1.00
52_E 70_L 1.65 1.00
23_P 53_F 1.642 1.00
57_Q 62_P 1.635 1.00
58_G 63_A 1.635 1.00
23_P 26_G 1.629 1.00
5_M 23_P 1.617 1.00
23_P 27_S 1.607 1.00
64_A 67_V 1.603 1.00
32_V 45_L 1.508 1.00
50_K 70_L 1.393 0.99
14_A 44_T 1.37 0.99
38_Q 68_V 1.365 0.99
12_F 34_F 1.301 0.99
23_P 28_K 1.282 0.99
34_F 37_I 1.226 0.98
6_T 24_D 1.184 0.98
14_A 42_F 1.182 0.98
39_S 69_T 1.18 0.98
46_N 49_Q 1.161 0.97
34_F 43_R 1.126 0.97
8_L 22_T 1.11 0.96
30_V 55_I 1.038 0.94
55_I 62_P 1.024 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2lssA1199.90.097Contact Map0.613
3camA20.957199.90.106Contact Map0.87
3i2zB2199.90.113Contact Map0.916
1h95A1199.90.122Contact Map0.587
1c9oA20.942999.80.127Contact Map0.879
2lxjA10.942999.80.128Contact Map0.556
3a0jA20.942999.80.142Contact Map0.835
1g6pA10.928699.80.143Contact Map0.507
2kcmA10.928699.80.149Contact Map0.504
3uljA2199.80.156Contact Map0.801

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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