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CSPC - Cold shock-like protein CspC
UniProt: P0A9Y6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12204
Length: 69 (67)
Sequences: 2993
Seq/Len: 44.67

CSPC
Paralog alert: 0.78 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: CSPA CSPB CSPC CSPD CSPE CSPF CSPG CSPH CSPI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_V 66_V 3.907 1.00
55_Q 64_V 3.87 1.00
53_E 65_N 2.735 1.00
48_Q 68_A 2.39 1.00
7_Q 49_N 2.313 1.00
23_A 49_N 2.249 1.00
13_E 45_A 2.145 1.00
5_K 51_E 2 1.00
51_E 67_T 1.912 1.00
35_A 64_V 1.856 1.00
51_E 69_I 1.813 1.00
5_K 49_N 1.753 1.00
22_P 25_G 1.73 1.00
56_D 61_P 1.728 1.00
37_Q 65_N 1.701 1.00
22_P 52_F 1.639 1.00
22_P 26_S 1.617 1.00
4_I 22_P 1.59 1.00
63_A 66_V 1.588 1.00
57_G 62_A 1.544 1.00
49_N 69_I 1.502 1.00
31_V 44_L 1.417 1.00
13_E 43_T 1.408 1.00
37_Q 67_T 1.381 0.99
11_F 33_F 1.28 0.99
33_F 36_I 1.268 0.99
5_K 23_A 1.248 0.99
7_Q 21_T 1.214 0.98
13_E 41_F 1.179 0.98
45_A 48_Q 1.137 0.97
33_F 42_K 1.128 0.97
38_G 68_A 1.062 0.95
35_A 55_Q 1.059 0.95
22_P 27_K 1.053 0.95
36_I 42_K 1.044 0.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3i2zB2199.90.083Contact Map0.902
3camA20.97199.90.089Contact Map0.85
1c9oA20.956599.90.109Contact Map0.865
2lssA1199.90.112Contact Map0.578
2lxjA10.956599.90.114Contact Map0.518
1h95A1199.80.127Contact Map0.543
3a0jA20.956599.80.128Contact Map0.804
1g6pA10.94299.80.131Contact Map0.461
3uljA2199.80.135Contact Map0.777
2kcmA10.94299.80.141Contact Map0.486

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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