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YOBA - Protein YobA
UniProt: P0AA57 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14029
Length: 124 (110)
Sequences: 666
Seq/Len: 6.05

YOBA
Paralog alert: 0.17 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
30_L 50_L 4.02 1.00
103_V 119_Y 2.785 1.00
28_A 54_E 2.759 1.00
62_G 106_H 2.44 1.00
106_H 114_K 2.292 1.00
33_Q 119_Y 2.237 1.00
28_A 110_V 2.163 1.00
40_Q 122_S 1.862 1.00
100_T 122_S 1.802 1.00
28_A 53_S 1.591 0.99
51_N 87_Q 1.57 0.99
17_T 20_V 1.554 0.99
68_P 99_G 1.523 0.99
31_T 53_S 1.518 0.99
48_I 65_I 1.507 0.99
105_W 117_G 1.503 0.99
34_Y 47_A 1.465 0.99
41_V 45_P 1.441 0.99
57_E 60_F 1.405 0.98
56_V 107_V 1.313 0.97
100_T 120_T 1.31 0.97
109_S 114_K 1.287 0.97
63_A 90_V 1.286 0.97
53_S 110_V 1.274 0.96
27_H 113_H 1.257 0.96
61_S 105_W 1.257 0.96
43_A 77_P 1.248 0.96
28_A 109_S 1.229 0.95
96_L 121_F 1.189 0.94
48_I 114_K 1.173 0.94
106_H 109_S 1.171 0.93
48_I 73_I 1.151 0.93
88_L 107_V 1.148 0.93
44_A 123_V 1.125 0.92
15_L 19_L 1.115 0.91
108_V 115_T 1.106 0.91
29_H 53_S 1.105 0.91
63_A 96_L 1.095 0.90
105_W 115_T 1.091 0.90
76_L 101_Y 1.085 0.89
60_F 109_S 1.077 0.89
32_H 51_N 1.074 0.89
62_G 102_T 1.068 0.88
37_A 119_Y 1.061 0.88
38_N 119_Y 1.06 0.88
30_L 33_Q 1.059 0.88
54_E 110_V 1.045 0.87
65_I 103_V 1.044 0.87
64_K 105_W 1.041 0.87
21_T 42_T 1.024 0.85
110_V 116_K 1.008 0.84
29_H 115_T 1.001 0.84
106_H 115_T 1 0.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1lyqA20.79031000.218Contact Map0.624
2c9rA10.78231000.231Contact Map0.579
4hu2A10.7594.90.828Contact Map0.385
3vynA20.7594.90.829Contact Map0.375
3c12A10.717791.70.848Contact Map0.081
3isyA10.854891.70.848Contact Map0.334
3osvA40.693589.50.856Contact Map0.041
3pddA10.693587.10.862Contact Map0.304
2vtcA20.943585.30.865Contact Map0.268
3m7oA40.927477.30.876Contact Map0.185

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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