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BHSA - Multiple stress resistance protein BhsA
UniProt: P0AB40 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13436
Length: 85 (85)
Sequences: 370
Seq/Len: 4.35

BHSA
Paralog alert: 0.97 [within 20: 0.48] - ratio of genomes with paralogs
Cluster includes: BHSA MCBA YAHO YBIJ YHCN YJFN YJFY
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
46_N 49_S 2.573 1.00
63_A 83_I 2.026 1.00
56_Q 60_E 1.984 1.00
73_G 77_L 1.853 1.00
18_F 22_A 1.802 1.00
21_F 25_E 1.794 1.00
35_K 82_V 1.739 0.99
41_A 50_L 1.677 0.99
55_A 59_D 1.555 0.98
47_L 79_G 1.536 0.98
1_M 9_A 1.396 0.96
1_M 5_K 1.383 0.96
52_E 56_Q 1.356 0.96
7_L 12_I 1.342 0.95
50_L 71_V 1.341 0.95
8_I 15_S 1.319 0.95
46_N 53_Q 1.317 0.95
51_E 68_I 1.317 0.95
69_T 80_T 1.292 0.94
67_R 82_V 1.282 0.94
34_Q 67_R 1.253 0.93
70_S 80_T 1.243 0.92
19_A 22_A 1.241 0.92
45_T 50_L 1.221 0.91
55_A 82_V 1.205 0.90
75_N 79_G 1.202 0.90
17_S 22_A 1.196 0.90
68_I 71_V 1.187 0.90
4_V 8_I 1.18 0.89
4_V 7_L 1.174 0.89
24_V 27_Q 1.16 0.88
5_K 11_A 1.149 0.87
48_G 83_I 1.142 0.87
50_L 77_L 1.119 0.86
50_L 73_G 1.113 0.85
64_K 85_K 1.105 0.85
17_S 21_F 1.095 0.84
1_M 4_V 1.079 0.83
26_V 67_R 1.059 0.81
16_M 19_A 1.059 0.81
79_G 83_I 1.044 0.80
54_L 79_G 1.014 0.77
14_S 85_K 1.013 0.77
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2nocA10.988299.90.076Contact Map0.393
2jnaA20.988299.90.096Contact Map0.36
2m2jA10.976599.80.255Contact Map0.479
2ma4A10.741299.80.288Contact Map0.472
4evuA20.899.80.3Contact Map0.589
2qgmA10.858821.60.887Contact Map0.022
3b55A10.858818.90.89Contact Map0.023
2jynA10.58828.60.906Contact Map0.199
4kzkA10.95296.70.91Contact Map0.31
3sg0A10.894160.912Contact Map0.078

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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