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ATPF - ATP synthase subunit b
UniProt: P0ABA0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10103
Length: 156 (156)
Sequences: 1928
Seq/Len: 12.36

ATPF
Paralog alert: 0.13 [within 20: 0.07] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_A 35_K 3.394 1.00
74_V 78_Q 2.48 1.00
49_R 53_D 2.48 1.00
41_A 45_A 2.452 1.00
48_E 52_K 2.399 1.00
141_D 144_A 2.228 1.00
94_A 98_R 2.144 1.00
89_E 93_E 2.132 1.00
98_R 101_I 2.1 1.00
34_E 38_K 2.088 1.00
58_K 62_T 2.006 1.00
42_D 46_S 1.954 1.00
110_E 114_K 1.95 1.00
38_K 42_D 1.944 1.00
99_T 103_A 1.939 1.00
84_S 88_D 1.846 1.00
63_D 67_K 1.812 1.00
56_L 60_S 1.792 1.00
34_E 37_Q 1.786 1.00
93_E 97_E 1.702 1.00
128_A 132_A 1.693 1.00
86_I 89_E 1.666 1.00
59_A 62_T 1.648 1.00
77_E 81_K 1.585 1.00
67_K 71_E 1.526 1.00
103_A 107_A 1.519 1.00
87_L 90_A 1.517 1.00
19_L 23_K 1.505 1.00
35_K 39_E 1.504 1.00
52_K 56_L 1.489 1.00
102_V 106_Q 1.476 1.00
138_R 144_A 1.47 1.00
128_A 131_G 1.427 1.00
71_E 74_V 1.404 0.99
45_A 48_E 1.398 0.99
15_V 19_L 1.386 0.99
88_D 92_A 1.375 0.99
19_L 22_M 1.374 0.99
60_S 64_Q 1.374 0.99
101_I 109_I 1.368 0.99
105_A 109_I 1.358 0.99
92_A 96_Q 1.358 0.99
151_K 155_E 1.358 0.99
81_K 85_Q 1.335 0.99
113_R 117_R 1.32 0.99
55_D 59_A 1.315 0.99
96_Q 100_K 1.305 0.99
95_E 99_T 1.298 0.99
45_A 49_R 1.295 0.99
77_E 80_N 1.291 0.99
119_E 123_Q 1.288 0.99
59_A 63_D 1.281 0.99
39_E 43_G 1.267 0.99
133_E 137_E 1.253 0.99
51_H 55_D 1.247 0.99
52_K 55_D 1.24 0.98
61_A 64_Q 1.238 0.98
104_Q 107_A 1.223 0.98
54_L 58_K 1.219 0.98
64_Q 67_K 1.214 0.98
37_Q 41_A 1.19 0.98
53_D 56_L 1.186 0.98
147_D 151_K 1.181 0.98
112_E 115_R 1.176 0.98
109_I 116_A 1.166 0.97
18_V 22_M 1.163 0.97
67_K 70_A 1.159 0.97
68_A 72_A 1.158 0.97
100_K 104_Q 1.156 0.97
124_V 128_A 1.154 0.97
144_A 147_D 1.152 0.97
87_L 91_K 1.15 0.97
46_S 50_A 1.13 0.97
103_A 106_Q 1.123 0.97
43_G 51_H 1.099 0.96
143_A 146_S 1.094 0.96
63_D 66_K 1.09 0.96
28_P 31_A 1.079 0.95
56_L 59_A 1.078 0.95
143_A 147_D 1.071 0.95
84_S 87_L 1.057 0.95
111_A 115_R 1.033 0.94
109_I 120_L 1.029 0.94
91_K 95_E 1.027 0.94
107_A 110_E 1.026 0.94
86_I 90_A 1.019 0.93
85_Q 89_E 1.016 0.93
73_Q 77_E 1.01 0.93
106_Q 110_E 1.007 0.93
6_T 10_Q 1.006 0.93
60_S 63_D 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1b9uA10.217998.50.696Contact Map0.666
2dm9A20.724498.20.72Contact Map0.506
2khkA10.3397980.736Contact Map0.345
1l2pA10.39197.70.755Contact Map0.517
3v6iA20.705197.30.77Contact Map0.536
2clyA20.923196.10.802Contact Map0.477
3v6iB20.673183.50.86Contact Map0.515
4efaE10.743675.40.871Contact Map0.631
2oarA50.551358.20.885Contact Map0.7
4efaG10.7540.60.896Contact Map0.446

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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