GREMLIN.BAKERLAB.org
Powered by OPENSEQ.org
BFR - Bacterioferritin
UniProt: P0ABD3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10113
Length: 158 (155)
Sequences: 827
Seq/Len: 5.34

BFR
Paralog alert: 0.23 [within 20: 0.06] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
57_R 122_E 3.348 1.00
84_E 88_R 3.115 1.00
4_D 111_V 2.258 1.00
82_D 85_E 2.209 1.00
107_Y 111_V 2.111 1.00
98_A 102_R 2.048 1.00
32_F 86_M 2.023 1.00
78_N 92_A 1.994 1.00
6_K 9_N 1.937 1.00
88_R 92_A 1.928 1.00
39_R 153_Q 1.926 1.00
84_E 146_L 1.855 1.00
37_L 150_L 1.817 1.00
98_A 131_I 1.757 1.00
16_G 20_V 1.75 1.00
104_A 120_M 1.738 1.00
49_I 52_M 1.651 0.99
144_M 154_I 1.641 0.99
91_L 135_E 1.623 0.99
6_K 111_V 1.605 0.99
30_R 56_D 1.59 0.99
84_E 142_Q 1.568 0.99
12_N 67_G 1.552 0.99
34_N 66_E 1.546 0.99
7_V 108_A 1.524 0.99
59_I 71_L 1.519 0.99
42_D 46_H 1.508 0.99
58_Y 119_M 1.492 0.99
51_E 130_H 1.49 0.99
33_K 60_E 1.482 0.99
50_D 126_D 1.454 0.98
50_D 53_K 1.426 0.98
141_I 146_L 1.422 0.98
51_E 54_H 1.42 0.98
99_K 103_E 1.351 0.97
10_Y 107_Y 1.351 0.97
15_L 62_I 1.342 0.97
37_L 143_K 1.32 0.96
51_E 94_E 1.298 0.96
109_D 117_R 1.29 0.96
98_A 127_E 1.286 0.96
139_D 143_K 1.275 0.95
118_D 121_I 1.272 0.95
96_D 100_N 1.258 0.95
31_M 63_L 1.256 0.95
4_D 107_Y 1.252 0.95
22_I 52_M 1.249 0.95
5_T 9_N 1.23 0.94
84_E 138_L 1.226 0.94
62_I 67_G 1.217 0.94
43_V 46_H 1.21 0.93
54_H 127_E 1.205 0.93
132_D 136_T 1.204 0.93
78_N 96_D 1.202 0.93
30_R 59_I 1.196 0.93
31_M 80_G 1.18 0.92
127_E 130_H 1.153 0.91
34_N 64_F 1.131 0.90
17_N 100_N 1.118 0.89
18_E 127_E 1.118 0.89
48_S 52_M 1.116 0.89
16_G 73_D 1.113 0.89
58_Y 116_S 1.108 0.89
2_K 66_E 1.097 0.88
113_D 116_S 1.093 0.88
13_K 100_N 1.092 0.88
6_K 107_Y 1.061 0.86
14_L 101_L 1.056 0.85
144_M 150_L 1.055 0.85
106_G 110_S 1.05 0.85
16_G 86_M 1.049 0.85
38_K 42_D 1.041 0.84
83_V 150_L 1.04 0.84
148_N 151_Q 1.039 0.84
10_Y 100_N 1.036 0.84
21_A 54_H 1.031 0.83
105_I 120_M 1.028 0.83
18_E 54_H 1.02 0.82
10_Y 104_A 1.015 0.82
54_H 130_H 1.014 0.82
49_I 56_D 1.013 0.82
50_D 54_H 1.012 0.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2v8tA20.9811000.43Contact Map0.484
2y3qA1211000.435Contact Map0.771
1o9iA60.9621000.444Contact Map0.657
2fkzA80.9811000.45Contact Map0.779
3fvbA211000.451Contact Map0.678
3r2kA10.96841000.452Contact Map0.568
3gvyA311000.455Contact Map0.799
4am5A211000.461Contact Map0.744
1jgcA311000.463Contact Map0.694
3vnxA111000.464Contact Map0.588

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0304 seconds.