GREMLIN.BAKERLAB.org
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BOLA - Protein BolA
UniProt: P0ABE2 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10125
Length: 105 (102)
Sequences: 966
Seq/Len: 9.47

BOLA
Paralog alert: 0.08 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: BOLA YRBA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
10_K 67_E 2.898 1.00
8_E 12_R 2.628 1.00
51_E 59_M 2.464 1.00
4_R 8_E 2.41 1.00
25_E 40_K 2.363 1.00
68_L 72_V 2.257 1.00
9_E 13_A 2.214 1.00
23_V 40_K 1.977 1.00
49_T 83_K 1.96 1.00
56_R 84_E 1.914 1.00
65_A 69_S 1.903 1.00
58_R 61_Y 1.896 1.00
4_R 24_D 1.855 1.00
54_L 58_R 1.793 1.00
17_P 20_L 1.789 1.00
15_F 43_L 1.717 1.00
51_E 55_N 1.702 1.00
5_E 8_E 1.664 1.00
61_Y 68_L 1.594 1.00
43_L 79_T 1.574 1.00
15_F 59_M 1.545 1.00
22_V 41_V 1.52 1.00
54_L 61_Y 1.464 1.00
46_D 82_I 1.436 1.00
56_R 79_T 1.419 0.99
7_I 64_L 1.392 0.99
21_E 42_V 1.374 0.99
47_R 51_E 1.358 0.99
25_E 76_A 1.319 0.99
46_D 49_T 1.309 0.99
57_H 77_L 1.308 0.99
52_R 55_N 1.285 0.99
55_N 58_R 1.279 0.99
40_K 76_A 1.204 0.98
38_H 75_L 1.181 0.97
24_D 36_E 1.17 0.97
27_Y 30_N 1.152 0.97
81_T 84_E 1.135 0.96
10_K 66_E 1.123 0.96
53_F 57_H 1.117 0.96
42_V 78_H 1.081 0.95
52_R 84_E 1.076 0.95
99_R 103_S 1.067 0.95
3_I 6_R 1.064 0.94
91_T 94_A 1.054 0.94
15_F 63_T 1.042 0.94
6_R 10_K 1.032 0.93
10_K 14_A 1.028 0.93
6_R 67_E 1.025 0.93
83_K 87_G 1.018 0.93
80_Y 85_W 1.016 0.92
31_V 35_S 1.016 0.92
42_V 80_Y 1.006 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2dhmA10.95241000.09Contact Map0.517
1v60A10.94291000.127Contact Map0.626
2kdnA10.8191000.274Contact Map0.562
3o2eA10.81000.275Contact Map0.743
1v9jA10.80951000.285Contact Map0.573
3tr3A20.752499.90.323Contact Map0.675
1xs3A10.723899.90.328Contact Map0.288
1ny8A10.876299.90.333Contact Map0.501
2mcqA10.723899.90.334Contact Map0.506
2kz0A10.685799.90.378Contact Map0.481

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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