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C561 - Cytochrome b561
UniProt: P0ABE5 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10172
Length: 176 (172)
Sequences: 1270
Seq/Len: 7.38

C561
Paralog alert: 0.76 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: C561 C56H C56I
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
157_A 162_W 4.184 1.00
102_L 106_Y 3.088 1.00
156_L 160_Y 3.065 1.00
20_V 94_F 2.802 1.00
16_V 56_M 2.681 1.00
9_Q 62_L 2.47 1.00
88_L 92_L 2.357 1.00
159_H 166_T 2.298 1.00
27_M 30_R 2.182 1.00
47_S 115_F 2.178 1.00
16_V 94_F 2.07 1.00
86_G 150_L 2.061 1.00
76_K 79_M 2.035 1.00
8_L 62_L 1.95 1.00
16_V 55_L 1.908 1.00
6_S 9_Q 1.853 1.00
159_H 167_L 1.84 1.00
81_G 84_H 1.834 1.00
6_S 62_L 1.819 1.00
56_M 94_F 1.795 1.00
6_S 66_Y 1.766 1.00
11_S 15_L 1.674 1.00
159_H 168_L 1.674 1.00
9_Q 66_Y 1.586 1.00
51_S 114_A 1.575 1.00
56_M 95_I 1.546 1.00
46_V 105_M 1.474 0.99
135_S 138_E 1.461 0.99
148_I 152_A 1.42 0.99
150_L 154_A 1.385 0.99
60_L 95_I 1.381 0.99
159_H 165_N 1.358 0.99
129_R 132_S 1.358 0.99
99_V 103_V 1.343 0.98
53_L 102_L 1.342 0.98
161_F 164_D 1.322 0.98
54_V 61_L 1.318 0.98
106_Y 122_A 1.31 0.98
166_T 169_R 1.31 0.98
85_L 88_L 1.31 0.98
28_E 33_F 1.288 0.98
37_D 41_I 1.288 0.98
103_V 133_L 1.275 0.98
83_A 86_G 1.264 0.97
144_G 148_I 1.253 0.97
77_P 81_G 1.247 0.97
86_G 154_A 1.233 0.97
28_E 32_F 1.225 0.97
126_N 129_R 1.221 0.97
34_P 38_R 1.214 0.96
62_L 66_Y 1.209 0.96
63_R 68_T 1.187 0.96
12_I 58_V 1.172 0.95
154_A 164_D 1.156 0.95
24_Y 148_I 1.151 0.95
27_M 32_F 1.149 0.95
23_A 52_I 1.132 0.94
146_F 150_L 1.131 0.94
26_A 34_P 1.129 0.94
5_Y 9_Q 1.117 0.94
91_Y 94_F 1.112 0.93
45_H 49_G 1.111 0.93
167_L 171_M 1.105 0.93
165_N 168_L 1.102 0.93
96_A 140_L 1.097 0.93
22_A 48_C 1.087 0.92
81_G 85_L 1.086 0.92
26_A 30_R 1.085 0.92
8_L 11_S 1.085 0.92
72_I 166_T 1.081 0.92
20_V 56_M 1.076 0.92
149_G 153_A 1.072 0.92
75_P 166_T 1.068 0.92
26_A 32_F 1.066 0.91
77_P 80_T 1.051 0.91
94_F 98_P 1.05 0.91
53_L 98_P 1.04 0.90
50_I 112_W 1.039 0.90
57_V 61_L 1.025 0.89
142_N 146_F 1.017 0.89
51_S 115_F 1.016 0.89
27_M 33_F 1.016 0.89
29_F 34_P 1.001 0.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4gd3A20.99431000.444Contact Map0.351
1kqfC10.897799.90.501Contact Map0.514
1q16C10.90918.50.948Contact Map0.445
3cx5C20.68187.50.949Contact Map0.441
1pp9C20.67613.40.957Contact Map0.378
2mc7A10.16482.50.959Contact Map0.322
2qjyA60.73862.30.96Contact Map0.47
3ideA50.295520.962Contact Map0.035
4h44A10.69891.80.963Contact Map0.426
3arcL20.21021.60.964Contact Map0.404

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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