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CDSA - Phosphatidate cytidylyltransferase
UniProt: P0ABG1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10139
Length: 285 (273)
Sequences: 1888
Seq/Len: 6.92

CDSA
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: CDSA YNBB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
8_S 254_I 6.085 1.00
167_G 199_T 4.373 1.00
193_F 232_V 3.639 1.00
238_E 250_S 3.427 1.00
178_H 191_Q 3.267 1.00
43_W 124_G 2.999 1.00
171_F 195_G 2.988 1.00
9_A 14_P 2.855 1.00
173_K 189_T 2.804 1.00
163_G 203_I 2.746 1.00
6_L 170_M 2.509 1.00
158_M 162_W 2.457 1.00
164_A 231_S 2.421 1.00
171_F 175_F 2.415 1.00
39_A 260_I 2.332 1.00
170_M 174_L 2.263 1.00
257_H 263_R 2.237 1.00
164_A 232_V 2.214 1.00
177_K 191_Q 2.189 1.00
10_F 14_P 2.108 1.00
157_V 271_V 2.072 1.00
179_K 187_G 2.054 1.00
180_L 236_L 1.991 1.00
171_F 199_T 1.883 1.00
41_W 251_G 1.83 1.00
46_L 250_S 1.732 1.00
7_I 11_V 1.719 1.00
38_L 260_I 1.707 1.00
178_H 190_W 1.707 1.00
2_L 170_M 1.697 1.00
194_I 198_A 1.692 1.00
237_T 241_F 1.666 1.00
9_A 13_I 1.632 1.00
164_A 228_A 1.627 1.00
2_L 6_L 1.592 1.00
161_V 270_A 1.572 1.00
168_A 196_G 1.568 1.00
23_L 27_G 1.532 0.99
46_L 247_I 1.514 0.99
3_K 7_I 1.479 0.99
159_I 203_I 1.477 0.99
41_W 45_Q 1.443 0.99
161_V 267_L 1.434 0.99
190_W 194_I 1.424 0.99
193_F 229_L 1.417 0.99
32_T 136_L 1.417 0.99
180_L 190_W 1.413 0.99
251_G 260_I 1.411 0.99
119_L 123_F 1.41 0.99
30_I 34_V 1.408 0.99
197_L 225_I 1.404 0.99
12_L 254_I 1.392 0.99
171_F 198_A 1.389 0.99
156_Y 224_S 1.364 0.98
231_S 266_S 1.35 0.98
264_I 267_L 1.344 0.98
44_G 59_A 1.304 0.98
157_V 274_F 1.304 0.98
179_K 182_P 1.298 0.98
46_L 245_A 1.295 0.98
4_Y 7_I 1.295 0.98
230_A 273_V 1.287 0.97
180_L 194_I 1.287 0.97
40_A 124_G 1.286 0.97
204_S 224_S 1.285 0.97
39_A 264_I 1.279 0.97
40_A 44_G 1.276 0.97
127_T 269_A 1.266 0.97
14_P 162_W 1.245 0.97
139_R 150_G 1.238 0.97
200_A 207_Y 1.232 0.96
166_S 199_T 1.23 0.96
171_F 174_L 1.216 0.96
195_G 266_S 1.214 0.96
206_G 210_W 1.211 0.96
220_L 224_S 1.201 0.96
200_A 228_A 1.196 0.96
162_W 257_H 1.191 0.95
163_G 199_T 1.189 0.95
6_L 10_F 1.188 0.95
39_A 261_L 1.176 0.95
131_F 134_G 1.16 0.95
9_A 170_M 1.157 0.94
173_K 187_G 1.152 0.94
176_G 191_Q 1.149 0.94
167_G 195_G 1.147 0.94
205_W 217_P 1.145 0.94
228_A 232_V 1.139 0.94
201_A 221_L 1.138 0.94
34_V 38_L 1.128 0.93
14_P 18_A 1.124 0.93
270_A 274_F 1.122 0.93
17_I 21_F 1.121 0.93
219_T 277_L 1.113 0.93
180_L 193_F 1.11 0.93
19_A 31_V 1.101 0.92
134_G 137_A 1.1 0.92
9_A 162_W 1.094 0.92
38_L 251_G 1.091 0.92
223_C 277_L 1.087 0.92
6_L 174_L 1.085 0.92
202_V 206_G 1.072 0.91
24_P 139_R 1.07 0.91
161_V 250_S 1.066 0.91
12_L 264_I 1.064 0.90
160_L 224_S 1.057 0.90
162_W 263_R 1.056 0.90
205_W 221_L 1.046 0.89
125_V 241_F 1.045 0.89
24_P 27_G 1.045 0.89
167_G 196_G 1.044 0.89
201_A 225_I 1.029 0.88
181_A 184_V 1.009 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1oisA10.21052.40.973Contact Map0.082
1skhA10.10531.60.976Contact Map0.937
2wswA10.21051.40.976Contact Map0.332
2ls2A10.08771.40.976Contact Map0.006
1iijA10.11931.40.977Contact Map0.327
1novD30.154410.978Contact Map0.977
2z2qB30.154410.979Contact Map0.974
1fqjC10.12630.90.979Contact Map0
2aghC10.08770.90.979Contact Map0.213
3h0dA20.18250.80.98Contact Map0.187

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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