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CCMB - Heme exporter protein B
UniProt: P0ABL8 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12058
Length: 220 (219)
Sequences: 493
Seq/Len: 2.25

CCMB
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
3_F 95_A 2.532 1.00
139_T 200_L 2.307 1.00
8_R 12_R 2.248 1.00
7_F 98_M 2.248 1.00
55_W 136_G 2.017 0.99
5_R 10_E 1.973 0.99
201_A 205_T 1.871 0.99
146_P 207_S 1.864 0.99
97_V 145_A 1.846 0.98
10_E 18_S 1.842 0.98
7_F 102_M 1.83 0.98
129_M 180_M 1.702 0.97
59_L 173_L 1.676 0.97
148_V 176_A 1.634 0.96
65_A 169_T 1.62 0.96
127_Q 131_L 1.608 0.95
205_T 209_F 1.543 0.94
102_M 186_H 1.526 0.93
147_G 165_V 1.465 0.92
3_F 7_F 1.461 0.91
28_F 58_A 1.432 0.90
152_V 164_L 1.422 0.90
47_A 119_L 1.409 0.89
10_E 120_G 1.407 0.89
66_L 144_G 1.404 0.89
31_V 154_L 1.404 0.89
178_A 192_Y 1.4 0.89
72_D 75_Q 1.398 0.89
62_S 65_A 1.388 0.88
68_R 72_D 1.384 0.88
194_A 198_A 1.369 0.87
31_V 152_V 1.357 0.87
88_P 213_A 1.356 0.87
132_T 176_A 1.325 0.85
106_L 214_A 1.302 0.84
62_S 93_V 1.298 0.83
31_V 57_A 1.294 0.83
37_L 111_L 1.27 0.81
54_I 115_V 1.267 0.81
25_L 136_G 1.256 0.80
40_G 68_R 1.255 0.80
4_W 8_R 1.253 0.80
97_V 141_G 1.253 0.80
49_I 104_T 1.252 0.80
158_G 162_S 1.249 0.80
82_L 162_S 1.249 0.80
83_M 219_I 1.234 0.79
96_K 147_G 1.234 0.79
212_A 217_I 1.217 0.77
97_V 211_T 1.213 0.77
163_I 207_S 1.205 0.76
6_I 95_A 1.204 0.76
84_L 116_A 1.192 0.75
94_L 188_P 1.191 0.75
131_L 134_L 1.169 0.73
197_G 217_I 1.164 0.73
142_F 204_A 1.16 0.73
11_L 106_L 1.16 0.73
118_L 152_V 1.157 0.72
152_V 156_R 1.15 0.72
151_T 161_L 1.134 0.70
36_P 46_L 1.123 0.69
162_S 203_T 1.121 0.69
2_M 211_T 1.117 0.68
145_A 212_A 1.114 0.68
25_L 84_L 1.11 0.68
80_E 142_F 1.109 0.68
151_T 154_L 1.108 0.68
9_L 163_I 1.1 0.67
6_I 220_Q 1.1 0.67
26_W 32_I 1.097 0.66
10_E 47_A 1.094 0.66
24_P 71_R 1.094 0.66
12_R 16_R 1.093 0.66
13_V 122_D 1.082 0.65
142_F 207_S 1.067 0.63
18_S 81_Q 1.06 0.63
197_G 201_A 1.059 0.62
52_G 56_V 1.059 0.62
170_I 195_I 1.053 0.62
96_K 215_L 1.051 0.62
15_F 209_F 1.051 0.62
11_L 204_A 1.05 0.61
113_P 147_G 1.049 0.61
109_L 134_L 1.048 0.61
99_A 144_G 1.046 0.61
189_V 193_L 1.045 0.61
188_P 205_T 1.044 0.61
11_L 110_I 1.043 0.61
34_L 197_G 1.041 0.60
50_A 122_D 1.035 0.60
31_V 137_T 1.035 0.60
179_A 215_L 1.034 0.60
134_L 138_P 1.034 0.60
197_G 200_L 1.031 0.59
73_D 137_T 1.028 0.59
122_D 132_T 1.027 0.59
8_R 134_L 1.024 0.59
143_L 169_T 1.023 0.58
83_M 89_L 1.022 0.58
20_E 80_E 1.02 0.58
29_L 118_L 1.019 0.58
39_I 164_L 1.017 0.58
21_I 220_Q 1.012 0.57
82_L 92_V 1.008 0.57
89_L 212_A 1.008 0.57
25_L 218_S 1.008 0.57
10_E 15_F 1 0.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2onkC40.68189.60.956Contact Map0.122
3w6jB40.27273.40.965Contact Map0.032
3zuxA10.79552.40.967Contact Map0.182
1pi7A10.081820.969Contact Map0
2ksfA10.43641.50.971Contact Map0.125
4i98B20.29551.30.972Contact Map0.001
3tx3A20.29091.10.973Contact Map0.318
3giaA10.35911.10.973Contact Map0.263
4h44B10.340910.974Contact Map0.102
3tuiA40.45910.80.976Contact Map0.284

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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