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CCMC - Heme exporter protein C
UniProt: P0ABM1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12057
Length: 245 (239)
Sequences: 604
Seq/Len: 2.53

CCMC
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
64_A 107_A 2.779 1.00
96_M 213_S 2.578 1.00
212_L 216_L 2.422 1.00
29_S 215_T 2.42 1.00
19_G 222_R 2.375 1.00
54_Y 58_Y 2.373 1.00
133_L 137_F 2.173 1.00
33_L 208_G 2.111 1.00
199_R 203_R 2.056 1.00
90_N 156_G 2.006 0.99
72_A 170_L 2.003 0.99
35_V 204_W 1.986 0.99
63_A 106_I 1.944 0.99
47_D 50_Q 1.897 0.99
127_A 182_T 1.839 0.99
235_V 238_L 1.837 0.99
78_A 93_V 1.821 0.99
75_A 167_V 1.82 0.99
32_V 211_L 1.809 0.99
79_F 83_V 1.764 0.98
124_V 129_L 1.725 0.98
170_L 173_I 1.712 0.98
105_F 109_V 1.697 0.98
67_S 132_E 1.69 0.98
132_E 136_L 1.672 0.97
207_F 211_L 1.653 0.97
96_M 217_T 1.653 0.97
205_S 208_G 1.62 0.97
28_A 211_L 1.613 0.96
75_A 138_L 1.534 0.95
26_A 215_T 1.5 0.94
54_Y 57_I 1.48 0.93
67_S 107_A 1.473 0.93
65_I 210_L 1.435 0.92
46_A 55_R 1.424 0.92
52_N 55_R 1.411 0.91
73_S 96_M 1.385 0.90
58_Y 198_M 1.381 0.90
93_V 142_V 1.364 0.89
172_I 179_W 1.345 0.88
149_F 155_A 1.323 0.87
36_G 205_S 1.31 0.86
174_H 178_E 1.301 0.86
15_Y 19_G 1.287 0.85
9_A 13_R 1.284 0.85
85_Q 157_R 1.276 0.84
177_V 185_Q 1.258 0.83
92_A 221_M 1.246 0.83
66_W 210_L 1.246 0.83
229_E 234_W 1.244 0.82
27_I 31_V 1.24 0.82
161_I 197_A 1.237 0.82
121_T 124_V 1.232 0.82
174_H 186_G 1.23 0.81
136_L 140_V 1.226 0.81
49_Q 118_M 1.222 0.81
79_F 164_L 1.219 0.81
189_R 199_R 1.219 0.81
39_W 43_F 1.218 0.81
102_V 208_G 1.213 0.80
70_I 96_M 1.206 0.80
90_N 146_W 1.193 0.79
71_Y 124_V 1.193 0.79
65_I 69_G 1.192 0.78
38_I 43_F 1.19 0.78
38_I 208_G 1.182 0.78
82_L 164_L 1.181 0.78
10_I 13_R 1.18 0.78
70_I 213_S 1.177 0.77
94_A 224_L 1.175 0.77
47_D 177_V 1.172 0.77
33_L 36_G 1.171 0.77
124_V 127_A 1.168 0.77
25_L 214_A 1.166 0.76
74_M 163_V 1.162 0.76
91_L 221_M 1.161 0.76
146_W 159_A 1.158 0.76
106_I 143_I 1.156 0.75
106_I 160_G 1.156 0.75
65_I 206_I 1.151 0.75
81_G 90_N 1.146 0.75
71_Y 127_A 1.128 0.73
132_E 174_H 1.122 0.72
24_W 27_I 1.119 0.72
108_L 133_L 1.114 0.72
137_F 149_F 1.114 0.72
100_G 139_Y 1.112 0.71
105_F 136_L 1.112 0.71
41_F 55_R 1.095 0.70
38_I 42_G 1.091 0.69
161_I 164_L 1.087 0.69
71_Y 100_G 1.084 0.69
7_Q 12_P 1.076 0.68
8_L 195_D 1.072 0.67
50_Q 117_P 1.07 0.67
165_I 228_M 1.056 0.66
26_A 29_S 1.047 0.65
26_A 30_V 1.043 0.64
71_Y 116_K 1.043 0.64
10_I 14_L 1.035 0.63
167_V 170_L 1.034 0.63
130_T 135_L 1.025 0.62
71_Y 131_S 1.024 0.62
109_V 113_A 1.023 0.62
237_E 241_K 1.017 0.61
53_S 118_M 1.015 0.61
17_I 21_F 1.004 0.60
194_I 198_M 1.003 0.60
169_N 172_I 1 0.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2xutA30.93478.60.971Contact Map0.156
4djkA20.95514.90.974Contact Map0.174
2kluA10.212230.977Contact Map0.213
2cfqA10.83272.90.977Contact Map0.134
3l1lA10.57962.10.979Contact Map0.229
4i9wA20.261220.979Contact Map0.236
2m20A20.18371.90.979Contact Map0.707
4i0uA100.32241.90.979Contact Map0.737
2c9lY20.11841.80.979Contact Map1
4ev6A50.33061.70.98Contact Map0.829

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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