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ARTQ - Arginine ABC transporter permease protein ArtQ
UniProt: P0AE34 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11626
Length: 238 (215)
Sequences: 8020
Seq/Len: 37.30

ARTQ
Paralog alert: 0.91 [within 20: 0.54] - ratio of genomes with paralogs
Cluster includes: ARTM ARTQ GLNP GLTJ GLTK HISM HISQ METI PHNE SSUC TAUC YECS YEHW
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
24_V 112_S 3.506 1.00
107_G 179_V 3.449 1.00
166_G 223_L 3.043 1.00
200_E 203_T 2.888 1.00
144_S 147_A 2.826 1.00
138_G 148_I 2.821 1.00
35_W 47_G 2.731 1.00
191_T 208_A 2.666 1.00
12_G 16_G 2.634 1.00
57_L 62_V 2.565 1.00
32_F 116_A 2.466 1.00
134_Q 156_Q 2.406 1.00
135_W 148_I 2.351 1.00
146_S 150_F 2.305 1.00
42_P 46_A 2.264 1.00
32_F 120_S 2.153 1.00
33_A 123_L 2.127 1.00
42_P 45_W 2.084 1.00
18_A 173_L 2.075 1.00
126_A 161_A 2.041 1.00
221_Y 225_R 1.994 1.00
51_V 120_S 1.989 1.00
36_E 48_S 1.897 1.00
129_A 160_H 1.866 1.00
102_S 105_L 1.806 1.00
213_L 217_L 1.796 1.00
8_A 12_G 1.794 1.00
18_A 176_T 1.76 1.00
28_L 116_A 1.743 1.00
135_W 139_Q 1.736 1.00
20_C 108_V 1.73 1.00
189_L 193_S 1.701 1.00
139_Q 148_I 1.682 1.00
11_A 215_I 1.678 1.00
16_G 104_F 1.677 1.00
13_M 16_G 1.661 1.00
66_I 110_A 1.657 1.00
119_A 165_L 1.651 1.00
195_A 201_P 1.624 1.00
225_R 228_L 1.613 1.00
217_L 221_Y 1.605 1.00
37_S 127_L 1.59 1.00
9_S 12_G 1.511 1.00
17_L 179_V 1.504 1.00
221_Y 224_K 1.504 1.00
144_S 148_I 1.497 1.00
22_L 169_W 1.488 1.00
57_L 114_L 1.479 1.00
222_I 225_R 1.476 1.00
37_S 128_K 1.446 1.00
41_R 45_W 1.426 1.00
191_T 204_W 1.424 1.00
145_K 149_F 1.415 1.00
121_Q 124_R 1.411 1.00
24_V 108_V 1.406 0.99
62_V 114_L 1.403 0.99
104_F 108_V 1.396 0.99
30_M 123_L 1.395 0.99
54_L 113_L 1.383 0.99
32_F 47_G 1.361 0.99
222_I 226_I 1.357 0.99
143_L 147_A 1.353 0.99
147_A 151_R 1.334 0.99
31_F 35_W 1.323 0.99
35_W 38_A 1.302 0.99
63_V 110_A 1.3 0.99
40_W 45_W 1.282 0.99
41_R 44_A 1.275 0.99
179_V 186_D 1.247 0.99
147_A 150_F 1.233 0.98
195_A 205_Y 1.194 0.98
225_R 229_R 1.188 0.98
36_E 121_Q 1.178 0.98
13_M 184_V 1.177 0.98
25_G 115_Y 1.173 0.98
123_L 161_A 1.171 0.98
139_Q 145_K 1.17 0.97
119_A 168_Q 1.152 0.97
177_A 212_Y 1.15 0.97
16_G 20_C 1.148 0.97
29_A 119_A 1.141 0.97
20_C 112_S 1.141 0.97
35_W 43_V 1.141 0.97
46_A 49_A 1.14 0.97
173_L 219_S 1.111 0.96
130_V 160_H 1.101 0.96
185_N 189_L 1.096 0.96
44_A 48_S 1.088 0.96
23_I 27_A 1.087 0.96
143_L 151_R 1.084 0.96
45_W 49_A 1.082 0.96
27_A 31_F 1.077 0.95
124_R 128_K 1.069 0.95
171_V 175_D 1.065 0.95
52_T 217_L 1.053 0.95
135_W 153_V 1.052 0.95
229_R 232_R 1.05 0.94
138_G 152_L 1.047 0.94
21_A 112_S 1.046 0.94
122_T 168_Q 1.045 0.94
190_Q 193_S 1.038 0.94
173_L 215_I 1.013 0.93
189_L 192_K 1.013 0.93
54_L 117_A 1.011 0.93
149_F 154_M 1.01 0.93
49_A 53_I 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3tuiA40.873999.90.63Contact Map0.789
2onkC40.924499.90.648Contact Map0.598
3rlfF10.941299.90.651Contact Map0.621
3d31C20.924499.90.654Contact Map0.545
3rlfG10.911899.80.686Contact Map0.504
3e7lA40.26475.60.964Contact Map0.605
3zjzA40.453840.966Contact Map0.34
2m8gX10.27733.40.967Contact Map0.476
4f4lA40.327730.968Contact Map0.285
4ltoA40.48742.80.969Contact Map0.547

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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