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BCP - Putative peroxiredoxin bcp
UniProt: P0AE52 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10108
Length: 156 (152)
Sequences: 10066
Seq/Len: 66.22

BCP
Paralog alert: 0.88 [within 20: 0.10] - ratio of genomes with paralogs
Cluster includes: AHPC BCP DSBE TPX
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
32_R 128_A 3.716 1.00
14_S 22_Q 2.952 1.00
10_A 103_F 2.742 1.00
31_Q 66_D 2.738 1.00
54_R 88_N 2.729 1.00
41_A 78_L 2.721 1.00
17_D 21_E 2.645 1.00
63_A 153_K 2.639 1.00
127_D 131_K 2.439 1.00
14_S 24_N 2.401 1.00
127_D 133_E 2.384 1.00
9_I 131_K 2.296 1.00
16_P 22_Q 2.208 1.00
57_M 61_K 2.003 1.00
24_N 27_D 1.96 1.00
5_K 8_D 1.941 1.00
12_K 26_T 1.904 1.00
98_Q 102_Q 1.83 1.00
12_K 24_N 1.817 1.00
56_N 59_E 1.77 1.00
126_I 132_I 1.722 1.00
108_E 115_T 1.703 1.00
15_L 92_L 1.695 1.00
33_V 66_D 1.637 1.00
23_V 28_F 1.589 1.00
110_S 115_T 1.564 1.00
75_P 79_S 1.528 1.00
18_Q 82_A 1.519 1.00
34_L 125_L 1.497 1.00
57_M 88_N 1.485 1.00
17_D 23_V 1.482 1.00
146_D 150_N 1.428 1.00
50_A 87_L 1.42 1.00
58_D 61_K 1.308 0.99
65_V 152_L 1.304 0.99
69_G 89_F 1.296 0.99
134_H 151_W 1.265 0.99
15_L 99_V 1.264 0.99
33_V 130_G 1.26 0.99
79_S 83_E 1.253 0.99
33_V 68_L 1.25 0.99
69_G 91_L 1.248 0.99
26_T 29_Q 1.243 0.98
28_F 33_V 1.233 0.98
52_G 56_N 1.228 0.98
61_K 66_D 1.212 0.98
28_F 68_L 1.207 0.98
72_T 100_C 1.206 0.98
56_N 146_D 1.206 0.98
52_G 55_D 1.202 0.98
107_G 120_H 1.199 0.98
12_K 25_L 1.197 0.98
29_Q 33_V 1.181 0.98
37_F 70_I 1.179 0.98
59_E 62_K 1.173 0.98
36_Y 123_S 1.171 0.98
16_P 75_P 1.162 0.97
42_M 80_R 1.139 0.97
54_R 58_D 1.135 0.97
100_C 119_I 1.122 0.97
76_E 80_R 1.117 0.96
47_T 85_E 1.117 0.96
72_T 97_H 1.109 0.96
17_D 90_T 1.092 0.96
58_D 88_N 1.084 0.96
17_D 92_L 1.075 0.95
80_R 83_E 1.063 0.95
33_V 126_I 1.062 0.95
74_K 77_K 1.06 0.95
32_R 125_L 1.054 0.95
56_N 145_H 1.051 0.94
49_Q 123_S 1.047 0.94
51_C 55_D 1.044 0.94
54_R 89_F 1.042 0.94
59_E 146_D 1.04 0.94
32_R 65_V 1.04 0.94
10_A 126_I 1.036 0.94
37_F 103_F 1.033 0.94
71_S 78_L 1.022 0.93
53_L 67_V 1.021 0.93
36_Y 49_Q 1.019 0.93
99_V 103_F 1.016 0.93
136_F 151_W 1.006 0.93
124_F 132_I 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1prxA20.99361000.206Contact Map0.697
2v2gA40.98721000.209Contact Map0.749
4h86A10.94231000.218Contact Map0.648
4gqcA40.98721000.22Contact Map0.871
2c0dA20.95511000.222Contact Map0.823
1xccA40.98721000.228Contact Map0.808
3ixrA111000.229Contact Map0.681
1xvwA20.96151000.233Contact Map0.778
1xiyA20.96791000.235Contact Map0.633
3tjjA50.96151000.235Contact Map0.825

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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