GREMLIN.BAKERLAB.org
Powered by OPENSEQ.org
CHAB - Cation transport regulator ChaB
UniProt: P0AE63 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12402
Length: 76 (76)
Sequences: 120
Seq/Len: 1.58

CHAB
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
25_Y 53_H 2.929 1.00
67_G 73_H 2.852 1.00
40_E 44_D 2.057 0.99
43_R 46_A 2.015 0.98
6_K 26_K 1.914 0.97
6_K 23_D 1.839 0.97
62_H 74_K 1.81 0.96
69_D 73_H 1.737 0.95
12_S 15_H 1.668 0.93
40_E 43_R 1.641 0.92
27_E 35_Q 1.555 0.90
1_M 21_A 1.537 0.89
3_Y 30_N 1.49 0.87
25_Y 33_W 1.486 0.87
65_A 75_K 1.46 0.85
13_V 31_S 1.388 0.81
39_K 44_D 1.352 0.79
40_E 46_A 1.335 0.77
59_A 66_K 1.33 0.77
46_A 51_T 1.303 0.75
31_S 34_D 1.255 0.71
54_K 66_K 1.238 0.69
29_F 49_E 1.197 0.66
33_W 48_R 1.191 0.65
70_D 76_S 1.189 0.65
3_Y 32_A 1.15 0.61
64_Y 72_W 1.142 0.60
38_D 43_R 1.128 0.59
32_A 36_Y 1.12 0.58
4_K 8_D 1.102 0.56
16_V 71_K 1.094 0.55
48_R 53_H 1.087 0.55
42_R 48_R 1.071 0.53
61_K 74_K 1.064 0.52
38_D 76_S 1.06 0.52
63_E 74_K 1.056 0.51
26_K 31_S 1.04 0.50
17_L 74_K 1.036 0.49
20_H 23_D 1.016 0.47
36_Y 66_K 1.004 0.46
65_A 73_H 1.003 0.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1sg7A111000.109Contact Map0.433
3aa0A10.98688.20.928Contact Map0.082
1zy7A20.78957.20.929Contact Map0.144
3l1nA10.47377.10.93Contact Map0.29
4djaA10.526370.93Contact Map0.283
1fc6A10.60535.70.933Contact Map0.184
4l8kA40.68425.50.933Contact Map0.138
4ld6A10.65794.90.935Contact Map0.169
1uvqC10.36844.70.935Contact Map0
2lh0A20.776340.938Contact Map0.087

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0154 seconds.