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CHEY - Chemotaxis protein CheY
UniProt: P0AE67 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10150
Length: 129 (122)
Sequences: 60519
Seq/Len: 496.06

CHEY
Paralog alert: 0.92 [within 20: 0.69] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
18_R 35_E 2.972 1.00
18_R 37_E 2.637 1.00
22_R 35_E 2.613 1.00
11_V 42_A 2.267 1.00
40_V 62_N 2.244 1.00
34_E 51_Y 2.123 1.00
38_D 62_N 2.039 1.00
63_M 71_T 2.021 1.00
59_N 89_E 1.965 1.00
76_G 79_S 1.964 1.00
56_S 68_L 1.916 1.00
47_Q 75_D 1.904 1.00
43_L 71_T 1.887 1.00
39_G 63_M 1.878 1.00
36_A 45_K 1.76 1.00
85_M 103_A 1.749 1.00
24_L 113_A 1.746 1.00
37_E 41_D 1.744 1.00
34_E 45_K 1.735 1.00
7_K 34_E 1.732 1.00
105_G 119_K 1.702 1.00
34_E 49_G 1.684 1.00
28_L 117_E 1.681 1.00
9_L 36_A 1.622 1.00
7_K 32_N 1.6 1.00
73_R 104_S 1.524 1.00
69_L 83_V 1.519 1.00
38_D 41_D 1.454 1.00
64_D 67_E 1.442 1.00
22_R 26_K 1.44 1.00
63_M 67_E 1.369 0.99
70_K 101_A 1.333 0.99
45_K 49_G 1.324 0.99
39_G 68_L 1.274 0.99
71_T 75_D 1.247 0.99
71_T 74_A 1.245 0.98
45_K 48_A 1.244 0.98
43_L 68_L 1.223 0.98
40_V 63_M 1.211 0.98
89_E 94_N 1.201 0.98
85_M 98_A 1.187 0.98
92_K 96_I 1.166 0.97
46_L 72_I 1.159 0.97
54_V 81_L 1.153 0.97
58_W 66_L 1.15 0.97
13_D 57_D 1.13 0.97
25_L 120_L 1.127 0.97
69_L 85_M 1.091 0.96
96_I 100_Q 1.086 0.96
66_L 97_A 1.084 0.96
7_K 49_G 1.077 0.95
36_A 42_A 1.074 0.95
45_K 51_Y 1.074 0.95
56_S 69_L 1.062 0.95
95_I 115_T 1.057 0.95
40_V 44_N 1.047 0.94
97_A 101_A 1.046 0.94
12_D 18_R 1.04 0.94
92_K 112_T 1.034 0.94
56_S 83_V 1.023 0.93
11_V 60_M 1.006 0.93
9_L 42_A 1.001 0.92
6_L 30_F 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3eq2A20.976799.7-0.012Contact Map0.711
2gwrA10.96999.70.001Contact Map0.694
1yioA10.96999.70.003Contact Map0.69
1ny5A20.93899.70.007Contact Map0.807
1w25A20.961299.70.008Contact Map0.788
3dzdA20.93899.60.012Contact Map0.802
3breA20.992299.60.021Contact Map0.673
1jbeA10.992299.60.021Contact Map0.798
4l4uA10.976799.60.023Contact Map0.722
3to5A10.984599.60.029Contact Map0.795

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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