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CREA - Protein CreA
UniProt: P0AE91 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11217
Length: 157 (148)
Sequences: 280
Seq/Len: 1.89

CREA
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
51_K 89_E 2.548 1.00
27_V 132_L 2.161 0.99
56_Y 149_A 2.003 0.99
119_V 134_Y 1.912 0.98
28_D 38_H 1.905 0.98
49_D 102_E 1.644 0.95
36_P 68_G 1.608 0.94
48_P 135_S 1.586 0.93
79_A 83_Q 1.57 0.93
46_D 126_R 1.445 0.88
137_K 140_E 1.44 0.88
42_V 130_A 1.435 0.87
58_S 78_A 1.347 0.83
12_L 15_L 1.341 0.82
8_L 15_L 1.334 0.82
36_P 39_K 1.333 0.82
88_I 128_A 1.325 0.81
112_V 138_V 1.313 0.80
95_K 98_K 1.303 0.80
44_A 48_P 1.3 0.79
10_L 13_I 1.287 0.78
23_E 41_V 1.283 0.78
16_G 154_P 1.281 0.78
97_G 124_A 1.256 0.76
66_K 125_K 1.252 0.76
28_D 37_D 1.249 0.75
78_A 116_L 1.242 0.75
8_L 14_M 1.233 0.74
9_S 14_M 1.217 0.73
8_L 13_I 1.21 0.72
9_S 13_I 1.208 0.72
126_R 143_P 1.207 0.72
144_K 150_V 1.199 0.71
130_A 147_I 1.194 0.71
32_K 38_H 1.181 0.69
8_L 102_E 1.181 0.69
9_S 12_L 1.179 0.69
111_L 138_V 1.177 0.69
8_L 11_S 1.171 0.69
11_S 76_S 1.165 0.68
30_V 38_H 1.161 0.68
40_I 75_T 1.153 0.67
153_M 156_R 1.151 0.67
14_M 17_P 1.151 0.67
46_D 125_K 1.149 0.66
40_I 118_V 1.143 0.66
116_L 133_A 1.137 0.65
128_A 149_A 1.134 0.65
117_Q 121_F 1.125 0.64
43_E 59_R 1.123 0.64
56_Y 153_M 1.122 0.64
43_E 46_D 1.113 0.63
44_A 54_T 1.103 0.62
108_R 115_S 1.103 0.62
38_H 117_Q 1.102 0.62
8_L 12_L 1.089 0.60
50_V 129_L 1.085 0.60
60_A 74_D 1.079 0.59
9_S 76_S 1.079 0.59
109_T 116_L 1.07 0.58
87_P 154_P 1.064 0.58
68_G 146_A 1.061 0.57
78_A 134_Y 1.048 0.56
41_V 59_R 1.046 0.56
30_V 138_V 1.041 0.55
17_P 20_H 1.035 0.54
11_S 18_L 1.032 0.54
92_D 104_V 1.027 0.54
10_L 17_P 1.021 0.53
22_E 112_V 1.018 0.53
13_I 16_G 1.016 0.52
56_Y 86_G 1.01 0.52
15_L 92_D 1.01 0.52
11_S 140_E 1.008 0.52
28_D 39_K 1.003 0.51
77_D 144_K 1 0.51
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4g56B20.33768.10.963Contact Map0
1dbgA10.73255.30.966Contact Map0.172
1v18B10.22293.50.969Contact Map0
4k3bA10.69433.30.969Contact Map0.051
3cnkA20.484130.97Contact Map0.007
2x3cA10.71972.80.97Contact Map0.054
3c75H20.80252.60.971Contact Map0.034
2r17C20.34392.30.971Contact Map0.265
2dlgA10.5352.10.972Contact Map0.093
1y0gA40.87920.972Contact Map0.18

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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