GREMLIN.BAKERLAB.org
Powered by OPENSEQ.org
FUCM - L-fucose mutarotase
UniProt: P0AEN8 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10355
Length: 140 (140)
Sequences: 667
Seq/Len: 4.76

FUCM
Paralog alert: 0.40 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: FUCM RBSD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
13_L 121_V 4.396 1.00
27_I 117_A 4.109 1.00
15_K 19_E 2.7 1.00
16_V 119_A 2.687 1.00
112_E 115_Q 2.292 1.00
25_E 113_R 2.1 1.00
59_P 92_A 2.083 1.00
12_E 41_Q 2.009 1.00
15_K 41_Q 1.972 1.00
25_E 135_K 1.927 1.00
35_A 42_V 1.899 1.00
70_L 135_K 1.678 0.99
109_A 112_E 1.625 0.99
27_I 33_F 1.623 0.99
86_E 104_R 1.572 0.99
26_I 61_F 1.558 0.99
52_D 55_Q 1.551 0.99
17_L 64_D 1.551 0.99
20_M 65_S 1.52 0.99
43_I 119_A 1.51 0.98
23_G 33_F 1.471 0.98
85_V 130_G 1.436 0.98
2_L 64_D 1.43 0.98
14_L 18_A 1.405 0.97
26_I 119_A 1.402 0.97
114_A 120_I 1.396 0.97
50_V 55_Q 1.381 0.97
25_E 133_L 1.365 0.96
47_G 60_L 1.357 0.96
11_P 42_V 1.351 0.96
20_M 136_K 1.333 0.96
20_M 26_I 1.322 0.96
24_D 118_F 1.317 0.95
27_I 110_F 1.308 0.95
87_R 91_N 1.294 0.95
20_M 24_D 1.278 0.94
33_F 110_F 1.271 0.94
45_A 53_L 1.271 0.94
11_P 14_L 1.26 0.94
10_S 46_D 1.256 0.94
75_A 104_R 1.217 0.92
7_P 63_L 1.167 0.90
11_P 15_K 1.167 0.90
27_I 133_L 1.16 0.90
58_I 134_L 1.144 0.89
19_E 42_V 1.143 0.89
75_A 82_D 1.135 0.88
12_E 15_K 1.124 0.88
71_V 75_A 1.114 0.87
16_V 43_I 1.096 0.86
106_N 109_A 1.086 0.85
31_A 130_G 1.084 0.85
31_A 49_L 1.08 0.85
37_S 118_F 1.076 0.84
73_M 77_E 1.063 0.83
26_I 43_I 1.061 0.83
37_S 116_K 1.059 0.83
47_G 59_P 1.056 0.83
34_P 129_Y 1.055 0.83
16_V 26_I 1.052 0.82
32_H 122_I 1.04 0.81
110_F 114_A 1.019 0.80
55_Q 96_Q 1.016 0.79
28_F 121_V 1.014 0.79
91_N 109_A 1.014 0.79
14_L 17_L 1.014 0.79
125_E 129_Y 1.006 0.78
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2wcuA211000.046Contact Map0.577
4a34A200.98571000.048Contact Map0.618
3mvkA100.99291000.058Contact Map0.614
2wcvA100.99291000.065Contact Map0.621
3dsaA150.951000.068Contact Map0.794
2ob5A111000.072Contact Map0.549
1ogdA50.92141000.088Contact Map0.629
3p12A40.92861000.089Contact Map0.649
3c3jA60.707115.30.939Contact Map0.257
3j31Q10.4120.942Contact Map0.001

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0246 seconds.