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GLNP - Glutamine transport system permease protein GlnP
UniProt: P0AEQ6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10388
Length: 219 (216)
Sequences: 8107
Seq/Len: 37.53

GLNP
Paralog alert: 0.91 [within 20: 0.54] - ratio of genomes with paralogs
Cluster includes: ARTM ARTQ GLNP GLTJ GLTK HISM HISQ METI PHNE SSUC TAUC YECS YEHW
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
32_G 98_M 3.551 1.00
93_A 165_F 3.441 1.00
152_G 209_L 3.086 1.00
130_S 133_E 2.849 1.00
124_G 134_T 2.809 1.00
186_R 189_E 2.766 1.00
177_G 194_V 2.708 1.00
43_A 55_A 2.702 1.00
20_K 24_W 2.629 1.00
65_T 70_Q 2.499 1.00
40_A 102_G 2.433 1.00
121_R 134_T 2.398 1.00
132_W 136_R 2.331 1.00
120_F 142_L 2.319 1.00
50_I 54_V 2.185 1.00
40_A 106_A 2.165 1.00
26_S 159_I 2.08 1.00
41_G 109_T 2.052 1.00
50_I 53_H 2.037 1.00
112_A 147_M 2.027 1.00
59_I 106_A 2.004 1.00
207_F 211_R 1.963 1.00
44_R 56_L 1.882 1.00
115_S 146_R 1.853 1.00
199_L 203_L 1.784 1.00
16_I 20_K 1.757 1.00
26_S 162_T 1.75 1.00
88_D 91_T 1.743 1.00
36_I 102_G 1.735 1.00
121_R 125_L 1.726 1.00
28_L 94_V 1.725 1.00
175_R 179_E 1.718 1.00
21_M 24_W 1.693 1.00
19_A 201_I 1.692 1.00
125_L 134_T 1.684 1.00
74_I 96_T 1.662 1.00
105_I 151_L 1.657 1.00
24_W 90_F 1.645 1.00
211_R 214_R 1.617 1.00
181_I 187_A 1.611 1.00
203_L 207_F 1.58 1.00
130_S 134_T 1.562 1.00
45_T 113_V 1.536 1.00
30_L 155_W 1.508 1.00
207_F 210_R 1.49 1.00
49_W 53_H 1.481 1.00
208_I 211_R 1.481 1.00
65_T 100_N 1.477 1.00
131_R 135_I 1.457 1.00
32_G 94_V 1.451 1.00
45_T 114_L 1.45 1.00
17_E 20_K 1.445 1.00
107_E 110_R 1.441 1.00
25_I 165_F 1.426 1.00
177_G 190_I 1.421 1.00
40_A 55_A 1.402 0.99
38_L 109_T 1.394 0.99
62_I 99_I 1.37 0.99
129_L 133_E 1.368 0.99
70_Q 100_N 1.365 0.99
90_F 94_V 1.344 0.99
133_E 137_Y 1.343 0.99
39_L 43_A 1.342 0.99
43_A 46_F 1.329 0.99
133_E 136_R 1.326 0.99
208_I 212_L 1.309 0.99
165_F 172_E 1.259 0.99
49_W 52_N 1.236 0.98
125_L 131_R 1.2 0.98
21_M 170_V 1.198 0.98
181_I 191_W 1.192 0.98
211_R 215_R 1.189 0.98
37_G 105_I 1.187 0.98
109_T 147_M 1.18 0.98
44_R 107_E 1.172 0.98
24_W 28_L 1.172 0.98
48_G 53_H 1.165 0.97
105_I 154_Q 1.165 0.97
28_L 98_M 1.165 0.97
71_V 96_T 1.161 0.97
163_S 198_Y 1.147 0.97
33_G 101_S 1.131 0.97
53_H 57_V 1.127 0.97
35_V 39_L 1.125 0.97
110_R 114_L 1.118 0.96
116_I 146_R 1.114 0.96
171_A 175_R 1.111 0.96
54_V 57_V 1.093 0.96
159_I 205_L 1.085 0.96
157_I 161_D 1.075 0.95
52_N 56_L 1.072 0.95
175_R 178_Q 1.069 0.95
60_E 203_L 1.066 0.95
31_A 35_V 1.06 0.95
43_A 51_A 1.057 0.95
91_T 95_V 1.052 0.95
121_R 139_I 1.051 0.94
135_I 140_L 1.041 0.94
108_I 154_Q 1.032 0.94
54_V 58_F 1.028 0.94
48_G 51_A 1.027 0.94
124_G 138_V 1.027 0.94
159_I 201_I 1.024 0.93
129_L 137_Y 1.023 0.93
176_Q 179_E 1.017 0.93
29_G 98_M 1.017 0.93
204_V 208_I 1.01 0.93
17_E 21_M 1.008 0.93
90_F 170_V 1.008 0.93
55_A 106_A 1.005 0.93
58_F 102_G 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3tuiA40.958999.90.616Contact Map0.769
3rlfF10.995499.90.633Contact Map0.612
2onkC40.981799.90.637Contact Map0.582
3d31C20.981799.90.643Contact Map0.532
3rlfG10.986399.80.67Contact Map0.5
3e7lA40.28774.50.963Contact Map0.597
3zjzA40.47032.70.967Contact Map0.345
4l5eA10.212.30.968Contact Map0.52
4ltoA40.50682.30.968Contact Map0.581
2m8gX10.30142.20.969Contact Map0.481

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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