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GLNQ - Glutamine transport ATP-binding protein GlnQ
UniProt: P10346 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10389
Length: 240 (238)
Sequences: 71291
Seq/Len: 299.54

GLNQ
Paralog alert: 0.94 [within 20: 0.84] - ratio of genomes with paralogs
Cluster includes: ARTP BTUD CCMA CYSA DDPD DDPF DPPD DPPF FBPC FECE FEPC FHUC FTSE GLNQ GLTL HISP LIVF LIVG LOLD LPTB MALK METN MLAF MODC NIKD NIKE OPPD OPPF PHNC PHNK PHNL POTA POTG PROV PSTB SAPD SAPF SSUB SUFC TAUB THIQ UGPC YADG YBBA YBBL YCJV YDCT YECC YEHX YHDZ YNJD ZNUC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_V 203_A 3.33 1.00
3_E 23_N 3.21 1.00
28_E 205_R 3.129 1.00
5_K 57_D 3.031 1.00
6_N 19_N 3.02 1.00
57_D 64_K 3.002 1.00
129_R 132_H 2.96 1.00
78_E 156_K 2.782 1.00
122_A 127_A 2.703 1.00
15_Q 18_H 2.696 1.00
30_V 207_I 2.663 1.00
3_E 59_I 2.611 1.00
18_H 213_R 2.61 1.00
25_A 28_E 2.551 1.00
205_R 217_D 2.393 1.00
8_S 19_N 2.384 1.00
4_F 7_V 2.374 1.00
218_G 222_V 2.27 1.00
116_L 154_K 2.194 1.00
9_K 46_C 2.145 1.00
10_H 15_Q 2.141 1.00
61_D 156_K 2.1 1.00
8_S 15_Q 2.086 1.00
94_A 137_L 2.048 1.00
121_L 130_A 2.036 1.00
118_R 130_A 2.01 1.00
8_S 55_S 1.989 1.00
219_N 222_V 1.981 1.00
95_L 131_H 1.954 1.00
5_K 59_I 1.915 1.00
207_I 214_I 1.915 1.00
26_Q 156_K 1.846 1.00
6_N 21_D 1.839 1.00
95_L 118_R 1.813 1.00
154_K 187_M 1.813 1.00
95_L 130_A 1.788 1.00
28_E 204_S 1.772 1.00
123_K 181_D 1.735 1.00
181_D 185_E 1.705 1.00
207_I 217_D 1.699 1.00
11_F 16_V 1.696 1.00
95_L 117_A 1.685 1.00
9_K 54_T 1.637 1.00
119_E 123_K 1.577 1.00
114_E 118_R 1.57 1.00
123_K 185_E 1.539 1.00
109_N 112_E 1.526 1.00
95_L 114_E 1.514 1.00
116_L 119_E 1.509 1.00
95_L 99_M 1.479 1.00
44_L 192_V 1.462 1.00
183_A 204_S 1.461 1.00
10_H 54_T 1.456 1.00
132_H 136_E 1.444 1.00
84_Q 139_G 1.439 1.00
17_L 46_C 1.437 1.00
24_I 30_V 1.418 1.00
22_L 207_I 1.407 0.99
59_I 64_K 1.399 0.99
9_K 51_E 1.398 0.99
115_K 119_E 1.39 0.99
5_K 23_N 1.387 0.99
4_F 47_I 1.372 0.99
193_T 199_A 1.366 0.99
46_C 53_I 1.362 0.99
99_M 117_A 1.35 0.99
218_G 223_L 1.343 0.99
99_M 113_A 1.34 0.99
98_V 152_A 1.294 0.99
4_F 22_L 1.292 0.99
44_L 159_L 1.288 0.99
8_S 18_H 1.281 0.99
61_D 78_E 1.273 0.99
93_T 96_E 1.259 0.99
30_V 217_D 1.252 0.99
127_A 130_A 1.248 0.99
118_R 122_A 1.245 0.98
160_F 179_M 1.224 0.98
97_N 149_R 1.21 0.98
5_K 21_D 1.208 0.98
7_V 53_I 1.193 0.98
47_I 190_V 1.188 0.98
116_L 120_L 1.178 0.98
120_L 152_A 1.172 0.98
46_C 58_L 1.171 0.98
29_V 183_A 1.167 0.97
43_L 209_I 1.159 0.97
9_K 42_T 1.158 0.97
94_A 145_V 1.149 0.97
129_R 141_Q 1.137 0.97
99_M 114_E 1.132 0.97
25_A 205_R 1.128 0.97
4_F 43_L 1.114 0.96
118_R 127_A 1.113 0.96
80_G 155_P 1.111 0.96
183_A 189_M 1.104 0.96
229_S 232_L 1.093 0.96
10_H 16_V 1.087 0.96
178_V 181_D 1.081 0.95
215_A 229_S 1.08 0.95
82_V 147_I 1.079 0.95
137_L 145_V 1.077 0.95
30_V 205_R 1.075 0.95
29_V 189_M 1.07 0.95
121_L 126_L 1.07 0.95
45_R 51_E 1.066 0.95
48_N 81_M 1.066 0.95
172_R 198_F 1.061 0.95
124_V 148_A 1.06 0.95
1_M 61_D 1.054 0.95
26_Q 61_D 1.051 0.94
98_V 121_L 1.049 0.94
180_Q 183_A 1.046 0.94
156_K 187_M 1.045 0.94
6_N 55_S 1.044 0.94
20_I 43_L 1.041 0.94
112_E 115_K 1.038 0.94
92_L 96_E 1.032 0.94
96_E 99_M 1.03 0.94
176_L 198_F 1.03 0.94
119_E 122_A 1.03 0.94
119_E 154_K 1.029 0.94
182_L 187_M 1.025 0.93
11_F 42_T 1.018 0.93
210_D 215_A 1.011 0.93
64_K 67_D 1.009 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2it1A20.9792100-0.05Contact Map0.863
2yyzA10.9792100-0.048Contact Map0.808
3tuiC40.9958100-0.048Contact Map0.876
1v43A10.9792100-0.048Contact Map0.825
1oxxK10.9958100-0.047Contact Map0.798
1g29120.9958100-0.046Contact Map0.89
1z47A20.9792100-0.043Contact Map0.837
3fvqA20.9958100-0.042Contact Map0.778
3rlfA20.9792100-0.04Contact Map0.835
2oljA21100-0.027Contact Map0.884

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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