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CYAY - Protein CyaY
UniProt: P27838 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11653
Length: 106 (106)
Sequences: 439
Seq/Len: 4.14

CYAY
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
59_Q 72_D 2.754 1.00
3_D 58_H 2.602 1.00
2_N 5_E 1.905 1.00
85_E 93_Q 1.84 1.00
86_T 89_D 1.8 1.00
6_F 55_E 1.74 0.99
66_Q 94_A 1.715 0.99
71_F 85_E 1.688 0.99
9_L 73_L 1.669 0.99
40_T 48_K 1.636 0.99
71_F 83_S 1.583 0.99
62_L 87_F 1.544 0.98
64_T 94_A 1.538 0.98
54_Q 57_L 1.53 0.98
63_A 68_G 1.459 0.97
93_Q 97_Q 1.455 0.97
12_Q 31_D 1.451 0.97
7_H 11_D 1.449 0.97
34_I 80_C 1.348 0.95
7_H 53_R 1.307 0.94
95_A 99_A 1.301 0.94
80_C 83_S 1.273 0.93
10_A 14_W 1.27 0.93
39_L 43_F 1.268 0.92
6_F 58_H 1.262 0.92
6_F 53_R 1.25 0.92
6_F 44_E 1.231 0.91
64_T 98_Q 1.204 0.90
37_G 59_Q 1.192 0.89
37_G 42_T 1.186 0.89
51_I 90_L 1.185 0.89
65_K 68_G 1.175 0.88
3_D 55_E 1.173 0.88
77_E 86_T 1.16 0.87
25_D 76_D 1.156 0.87
59_Q 81_D 1.156 0.87
44_E 47_S 1.136 0.86
22_D 32_C 1.13 0.85
18_E 25_D 1.124 0.85
37_G 57_L 1.121 0.85
38_V 67_G 1.109 0.84
39_L 82_R 1.108 0.84
33_E 55_E 1.089 0.82
16_T 102_T 1.089 0.82
64_T 67_G 1.064 0.80
73_L 79_I 1.061 0.80
21_L 24_W 1.056 0.79
19_E 40_T 1.049 0.79
13_L 69_Y 1.045 0.78
15_L 89_D 1.042 0.78
38_V 48_K 1.039 0.78
63_A 69_Y 1.02 0.76
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ew4A111000.019Contact Map0.481
4jpdA111000.02Contact Map0.456
4hs5A20.98111000.029Contact Map0.545
3t3lA111000.041Contact Map0.477
3oeqA10.97171000.098Contact Map0.248
2pt7G20.9245130.929Contact Map0.095
4i66A10.405711.60.93Contact Map0.184
1n10A20.971710.40.932Contact Map0.119
4g08A10.33028.50.934Contact Map0.739
1xkpB10.7838.40.935Contact Map0.221

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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