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ASMA - Protein AsmA
UniProt: P28249 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11361
Length: 617 (600)
Sequences: 804
Seq/Len: 1.34

ASMA
Paralog alert: 0.51 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: ASMA YHJG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
109_A 155_S 4.524 1.00
47_L 70_L 3.537 1.00
83_D 108_G 3.447 1.00
359_D 379_K 3.309 1.00
403_Q 433_D 3.017 1.00
436_G 447_N 2.916 1.00
337_Q 369_G 2.776 1.00
108_G 154_D 2.691 1.00
264_N 296_L 2.475 1.00
284_L 343_I 2.467 1.00
50_D 67_R 2.443 1.00
116_Q 120_V 2.41 1.00
21_A 25_L 2.404 0.99
39_V 47_L 2.384 0.99
119_A 122_S 2.245 0.99
40_A 46_Q 2.133 0.99
90_A 93_P 2.054 0.98
509_L 536_T 2.028 0.98
436_G 444_F 2.017 0.98
39_V 70_L 2.015 0.98
43_S 70_L 1.94 0.97
381_N 417_A 1.923 0.97
450_G 505_G 1.91 0.96
512_M 523_G 1.905 0.96
272_A 284_L 1.89 0.96
107_K 154_D 1.84 0.95
293_L 297_I 1.824 0.95
346_Q 361_A 1.818 0.95
289_P 348_S 1.812 0.95
108_G 155_S 1.809 0.95
452_A 500_L 1.805 0.95
279_K 340_T 1.769 0.94
366_N 371_L 1.742 0.93
288_F 296_L 1.74 0.93
40_A 47_L 1.725 0.93
29_N 52_P 1.711 0.92
370_L 394_T 1.709 0.92
270_G 286_L 1.708 0.92
14_V 434_F 1.692 0.92
281_E 340_T 1.686 0.92
565_V 574_Y 1.679 0.91
405_R 431_A 1.627 0.90
568_N 572_L 1.609 0.89
292_N 351_R 1.598 0.88
107_K 153_A 1.589 0.88
285_R 344_L 1.569 0.87
500_L 509_L 1.528 0.85
7_T 11_L 1.527 0.85
22_L 25_L 1.526 0.85
13_V 17_A 1.515 0.85
313_G 316_Q 1.51 0.84
370_L 392_D 1.495 0.84
288_F 347_A 1.481 0.83
454_V 498_T 1.48 0.83
296_L 366_N 1.465 0.82
528_N 531_D 1.465 0.82
410_E 413_T 1.447 0.81
269_S 287_Q 1.441 0.80
257_N 528_N 1.439 0.80
287_Q 346_Q 1.427 0.79
593_R 597_W 1.425 0.79
287_Q 348_S 1.417 0.79
379_K 384_Q 1.413 0.79
45_Y 79_L 1.41 0.78
93_P 99_L 1.409 0.78
369_G 393_A 1.402 0.78
239_G 243_F 1.398 0.77
67_R 83_D 1.39 0.77
29_N 53_L 1.387 0.77
43_S 79_L 1.382 0.76
11_L 16_V 1.38 0.76
29_N 51_G 1.375 0.76
43_S 80_V 1.366 0.75
169_I 172_I 1.362 0.75
434_F 450_G 1.359 0.75
333_Y 393_A 1.352 0.74
593_R 596_D 1.35 0.74
39_V 43_S 1.35 0.74
342_D 363_Q 1.344 0.73
339_F 366_N 1.336 0.73
598_A 601_N 1.331 0.72
21_A 157_L 1.329 0.72
263_A 296_L 1.325 0.72
336_L 369_G 1.325 0.72
115_P 436_G 1.312 0.71
89_V 535_D 1.307 0.70
566_Y 573_N 1.307 0.70
4_F 8_L 1.299 0.70
402_F 434_F 1.295 0.69
10_I 95_L 1.292 0.69
283_Q 342_D 1.29 0.69
458_D 517_P 1.29 0.69
112_Q 158_V 1.288 0.69
121_R 126_P 1.282 0.68
523_G 538_F 1.274 0.68
37_K 41_A 1.272 0.67
264_N 295_N 1.272 0.67
592_R 599_E 1.265 0.67
596_D 599_E 1.265 0.67
113_L 125_A 1.264 0.67
594_L 598_A 1.263 0.67
591_K 596_D 1.263 0.67
179_D 205_G 1.263 0.67
172_I 469_M 1.263 0.67
445_R 532_Q 1.259 0.66
588_D 596_D 1.256 0.66
438_D 450_G 1.256 0.66
516_S 519_L 1.253 0.66
348_S 359_D 1.25 0.66
332_A 463_G 1.25 0.66
90_A 172_I 1.242 0.65
169_I 203_L 1.24 0.65
47_L 71_T 1.237 0.64
43_S 47_L 1.232 0.64
543_V 550_S 1.23 0.64
70_L 184_G 1.228 0.64
22_L 26_V 1.228 0.64
502_L 507_V 1.228 0.64
65_S 68_M 1.227 0.63
16_V 500_L 1.223 0.63
499_D 511_D 1.222 0.63
55_W 143_W 1.222 0.63
465_N 468_Q 1.222 0.63
31_F 34_Y 1.219 0.63
28_P 31_F 1.218 0.63
332_A 335_G 1.215 0.62
45_Y 71_T 1.209 0.62
595_N 598_A 1.208 0.62
590_A 598_A 1.202 0.61
1_M 7_T 1.2 0.61
378_G 385_V 1.198 0.61
565_V 572_L 1.196 0.60
23_V 55_W 1.193 0.60
520_A 543_V 1.192 0.60
87_L 507_V 1.191 0.60
589_E 592_R 1.179 0.59
357_F 360_V 1.174 0.58
14_V 160_Q 1.172 0.58
535_D 566_Y 1.171 0.58
2_R 480_D 1.171 0.58
6_T 10_I 1.168 0.58
492_R 549_E 1.163 0.57
374_T 390_T 1.161 0.57
369_G 392_D 1.161 0.57
161_H 233_P 1.159 0.57
585_H 592_R 1.158 0.57
13_V 16_V 1.157 0.57
587_Q 593_R 1.156 0.57
8_L 16_V 1.154 0.56
588_D 591_K 1.153 0.56
465_N 491_T 1.152 0.56
50_D 69_S 1.152 0.56
410_E 427_K 1.146 0.56
4_F 7_T 1.145 0.55
264_N 366_N 1.144 0.55
452_A 507_V 1.143 0.55
332_A 398_P 1.141 0.55
122_S 125_A 1.139 0.55
101_V 433_D 1.138 0.55
463_G 467_Q 1.138 0.55
271_Q 285_R 1.132 0.54
465_N 471_Q 1.132 0.54
46_Q 71_T 1.131 0.54
209_A 537_Q 1.13 0.54
45_Y 459_T 1.13 0.54
467_Q 471_Q 1.127 0.54
290_Q 349_N 1.127 0.54
233_P 376_L 1.126 0.54
51_G 67_R 1.125 0.54
66_G 84_N 1.124 0.53
9_M 14_V 1.124 0.53
58_W 61_L 1.121 0.53
270_G 452_A 1.119 0.53
40_A 48_Q 1.119 0.53
94_L 535_D 1.118 0.53
471_Q 517_P 1.117 0.53
80_V 409_V 1.116 0.53
59_P 465_N 1.112 0.52
264_N 267_T 1.112 0.52
459_T 493_L 1.108 0.52
294_D 354_G 1.106 0.52
406_L 526_M 1.105 0.52
381_N 413_T 1.104 0.51
537_Q 577_Q 1.101 0.51
12_L 367_K 1.101 0.51
309_A 316_Q 1.099 0.51
428_M 456_M 1.098 0.51
5_L 8_L 1.098 0.51
382_G 413_T 1.096 0.51
364_M 577_Q 1.095 0.50
9_M 13_V 1.094 0.50
59_P 323_V 1.094 0.50
55_W 59_P 1.094 0.50
590_A 597_W 1.092 0.50
37_K 145_F 1.089 0.50
29_N 32_R 1.088 0.50
466_F 535_D 1.088 0.50
106_L 291_L 1.086 0.50
115_P 119_A 1.085 0.49
438_D 459_T 1.083 0.49
292_N 295_N 1.077 0.49
116_Q 119_A 1.076 0.49
29_N 55_W 1.074 0.48
44_G 78_P 1.073 0.48
243_F 477_N 1.071 0.48
150_L 529_L 1.069 0.48
415_L 491_T 1.069 0.48
94_L 562_P 1.068 0.48
264_N 288_F 1.068 0.48
92_L 95_L 1.067 0.48
533_T 568_N 1.067 0.48
110_V 156_V 1.066 0.48
411_I 456_M 1.062 0.47
199_L 568_N 1.06 0.47
374_T 388_P 1.06 0.47
4_F 12_L 1.059 0.47
65_S 69_S 1.059 0.47
17_A 21_A 1.058 0.47
144_S 405_R 1.057 0.47
190_G 288_F 1.056 0.47
31_F 53_L 1.054 0.46
104_V 261_L 1.052 0.46
333_Y 398_P 1.05 0.46
75_A 114_T 1.05 0.46
10_I 14_V 1.049 0.46
223_I 243_F 1.049 0.46
567_G 572_L 1.049 0.46
345_L 466_F 1.049 0.46
347_A 357_F 1.046 0.46
115_P 160_Q 1.046 0.46
590_A 593_R 1.046 0.46
434_F 502_L 1.045 0.45
57_V 529_L 1.043 0.45
55_W 465_N 1.042 0.45
3_R 7_T 1.04 0.45
34_Y 38_Q 1.039 0.45
27_N 375_Q 1.038 0.45
107_K 172_I 1.036 0.45
498_T 509_L 1.035 0.44
375_Q 569_W 1.035 0.44
149_S 157_L 1.033 0.44
136_D 140_D 1.033 0.44
543_V 549_E 1.032 0.44
14_V 265_D 1.028 0.44
520_A 549_E 1.028 0.44
365_T 374_T 1.027 0.44
85_M 430_L 1.027 0.44
495_R 515_Q 1.026 0.44
491_T 523_G 1.024 0.43
441_A 445_R 1.023 0.43
115_P 121_R 1.021 0.43
49_L 85_M 1.021 0.43
267_T 288_F 1.02 0.43
82_A 564_R 1.02 0.43
464_M 493_L 1.019 0.43
113_L 391_L 1.018 0.43
588_D 593_R 1.017 0.43
58_W 448_W 1.017 0.43
585_H 598_A 1.017 0.43
316_Q 320_P 1.014 0.42
579_D 583_R 1.013 0.42
597_W 600_R 1.013 0.42
90_A 205_G 1.013 0.42
309_A 313_G 1.012 0.42
3_R 6_T 1.011 0.42
593_R 599_E 1.011 0.42
23_V 28_P 1.009 0.42
337_Q 394_T 1.008 0.42
511_D 536_T 1.008 0.42
406_L 431_A 1.008 0.42
381_N 459_T 1.007 0.42
399_R 402_F 1.004 0.41
589_E 593_R 1.004 0.41
442_D 446_H 1.004 0.41
1_M 25_L 1.002 0.41
428_M 493_L 1.002 0.41
532_Q 570_Q 1.001 0.41
152_V 171_N 1 0.41
38_Q 41_A 1 0.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
1spfA10.042113.30.977Contact Map0.555
4m4dA20.29019.20.978Contact Map0.213
1s5lU20.19297.70.979Contact Map0.08
2kncA10.06656.50.98Contact Map0.488
1pi7A10.05835.60.98Contact Map0.545
2jobA10.16215.60.98Contact Map0.24
3j2wE40.05025.40.98Contact Map0.252
1ewfA10.29344.70.981Contact Map0.186
1ixsA10.09440.982Contact Map0.308
1pzqA20.07133.80.982Contact Map0.244

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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