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BASS - Sensor protein BasS
UniProt: P30844 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11614
Length: 363 (295)
Sequences: 10333
Seq/Len: 35.03

BASS
Paralog alert: 0.90 [within 20: 0.14] - ratio of genomes with paralogs
Cluster includes: ATOS BAES BASS CPXA CREC CUSS DCUS DPIB ENVZ GLRK NTRB PHOQ PHOR QSEC RSTB YEDV ZRAS
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
291_D 295_G 3.622 1.00
326_S 330_Q 3.328 1.00
290_E 348_R 3.316 1.00
269_S 292_E 2.913 1.00
325_V 336_F 2.834 1.00
301_C 340_N 2.787 1.00
337_F 350_W 2.622 1.00
338_L 349_A 2.603 1.00
284_G 352_R 2.48 1.00
305_S 336_F 2.478 1.00
257_L 329_T 2.477 1.00
162_R 184_D 2.385 1.00
288_A 348_R 2.334 1.00
249_G 332_H 2.326 1.00
281_E 355_K 2.321 1.00
211_V 249_G 2.321 1.00
257_L 328_I 2.25 1.00
165_L 179_L 2.231 1.00
269_S 273_S 2.201 1.00
278_K 288_A 2.197 1.00
329_T 334_G 2.182 1.00
329_T 351_V 2.177 1.00
276_M 290_E 2.13 1.00
278_K 290_E 2.12 1.00
274_N 292_E 2.095 1.00
340_N 347_T 2.087 1.00
303_E 306_K 2.084 1.00
288_A 350_W 2.064 1.00
339_Q 350_W 2.044 1.00
286_V 352_R 2.043 1.00
209_Q 251_A 2.041 1.00
297_D 300_K 2.009 1.00
237_L 276_M 1.992 1.00
120_L 123_E 1.958 1.00
296_I 304_L 1.952 1.00
237_L 274_N 1.92 1.00
249_G 254_L 1.916 1.00
339_Q 348_R 1.914 1.00
104_A 109_N 1.902 1.00
210_H 248_Q 1.851 1.00
334_G 353_L 1.846 1.00
301_C 338_L 1.824 1.00
341_R 345_S 1.819 1.00
105_R 133_V 1.808 1.00
145_L 149_D 1.77 1.00
335_Q 352_R 1.765 1.00
210_H 246_T 1.703 1.00
239_P 276_M 1.687 1.00
263_E 267_R 1.683 1.00
286_V 350_W 1.675 1.00
162_R 187_M 1.655 1.00
280_Q 286_V 1.648 1.00
220_P 255_R 1.646 1.00
235_T 274_N 1.626 1.00
153_E 256_M 1.616 1.00
112_P 137_T 1.61 1.00
112_P 134_S 1.602 1.00
257_L 351_V 1.594 1.00
212_K 216_D 1.584 1.00
208_Y 248_Q 1.583 1.00
291_D 346_G 1.57 1.00
280_Q 288_A 1.566 1.00
229_L 266_H 1.564 1.00
258_L 287_M 1.555 1.00
300_K 303_E 1.535 1.00
99_Q 124_A 1.535 1.00
328_I 332_H 1.531 1.00
305_S 349_A 1.523 1.00
239_P 278_K 1.519 1.00
273_S 292_E 1.519 1.00
105_R 132_L 1.512 1.00
298_E 301_C 1.487 1.00
300_K 309_V 1.48 1.00
296_I 347_T 1.474 1.00
84_C 88_V 1.467 1.00
212_K 244_D 1.461 1.00
300_K 311_M 1.45 1.00
330_Q 335_Q 1.445 1.00
287_M 351_V 1.444 1.00
304_L 338_L 1.44 1.00
338_L 347_T 1.438 1.00
162_R 183_L 1.428 1.00
119_T 123_E 1.425 1.00
169_A 177_A 1.408 1.00
268_Y 310_R 1.4 0.99
257_L 325_V 1.395 0.99
329_T 336_F 1.394 0.99
149_D 307_A 1.379 0.99
161_V 183_L 1.359 0.99
276_M 292_E 1.357 0.99
303_E 309_V 1.356 0.99
260_N 325_V 1.356 0.99
305_S 338_L 1.344 0.99
253_L 256_M 1.341 0.99
111_T 137_T 1.334 0.99
187_M 191_S 1.331 0.99
102_L 129_L 1.325 0.99
169_A 180_V 1.318 0.99
225_L 259_R 1.304 0.99
118_A 123_E 1.283 0.99
285_A 355_K 1.278 0.99
254_L 332_H 1.274 0.99
337_F 352_R 1.251 0.99
146_F 150_V 1.241 0.98
137_T 141_D 1.23 0.98
130_N 133_V 1.23 0.98
103_E 124_A 1.212 0.98
112_P 133_V 1.21 0.98
206_G 250_D 1.207 0.98
98_L 129_L 1.193 0.98
129_L 132_L 1.181 0.98
102_L 128_A 1.18 0.98
99_Q 128_A 1.176 0.98
320_L 324_I 1.161 0.97
245_I 279_L 1.16 0.97
261_L 349_A 1.144 0.97
296_I 300_K 1.138 0.97
291_D 347_T 1.128 0.97
212_K 246_T 1.127 0.97
101_E 113_I 1.12 0.96
340_N 345_S 1.117 0.96
301_C 305_S 1.109 0.96
250_D 253_L 1.107 0.96
114_A 130_N 1.102 0.96
102_L 132_L 1.089 0.96
224_E 255_R 1.084 0.96
166_E 180_V 1.074 0.95
143_E 147_T 1.071 0.95
188_E 252_T 1.07 0.95
233_Q 272_G 1.068 0.95
253_L 328_I 1.063 0.95
229_L 275_I 1.058 0.95
160_G 164_H 1.052 0.95
284_G 335_Q 1.051 0.94
222_Y 277_I 1.045 0.94
305_S 326_S 1.042 0.94
165_L 183_L 1.039 0.94
88_V 92_T 1.035 0.94
214_L 219_L 1.035 0.94
179_L 183_L 1.032 0.94
112_P 130_N 1.026 0.94
106_T 131_D 1.02 0.93
220_P 251_A 1.018 0.93
135_R 138_S 1.01 0.93
258_L 262_V 1.009 0.93
192_Q 253_L 1.007 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4i5sA20.8431000.378Contact Map0.826
4ew8A20.70251000.488Contact Map0.825
2btzA10.83751000.489Contact Map0.63
3jz3A20.59231000.493Contact Map0.69
4e01A10.95871000.514Contact Map0.651
2q8gA10.8651000.516Contact Map0.625
2c2aA10.65561000.52Contact Map0.772
2e0aA20.85121000.523Contact Map0.664
3d36A20.61981000.526Contact Map0.773
4gczA20.94211000.535Contact Map0.738

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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