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CCMF - Cytochrome c-type biogenesis protein CcmF
UniProt: P33927 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12054
Length: 647 (638)
Sequences: 722
Seq/Len: 1.13

CCMF
Paralog alert: 0.46 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: CCMF NRFE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
184_F 256_G 4.14 1.00
64_N 84_R 4.095 1.00
70_Y 91_A 3.597 1.00
515_M 519_D 3.249 1.00
81_V 85_V 3.16 1.00
58_V 88_T 3.132 1.00
62_V 85_V 3.075 1.00
233_E 576_E 2.973 1.00
224_V 617_G 2.841 1.00
135_G 318_F 2.706 1.00
255_V 283_A 2.608 1.00
77_T 157_E 2.537 1.00
138_L 142_F 2.489 0.99
545_V 563_E 2.399 0.99
531_R 549_G 2.394 0.99
503_F 609_F 2.359 0.99
83_Y 168_P 2.354 0.99
517_S 530_F 2.346 0.99
62_V 81_V 2.315 0.99
74_N 91_A 2.262 0.99
20_L 46_L 2.244 0.99
51_A 101_L 2.213 0.98
482_F 629_F 2.202 0.98
16_I 49_S 2.201 0.98
79_L 87_A 2.177 0.98
262_S 356_N 2.168 0.98
581_G 611_R 2.144 0.98
351_L 412_V 2.104 0.98
562_A 578_A 2.089 0.97
184_F 283_A 2.045 0.97
59_N 63_V 2.023 0.97
21_S 131_M 1.987 0.96
8_G 12_L 1.941 0.96
407_G 465_L 1.932 0.95
221_L 621_A 1.928 0.95
548_I 589_A 1.904 0.95
328_L 332_A 1.904 0.95
560_L 578_A 1.881 0.94
45_L 49_S 1.859 0.94
16_I 45_L 1.816 0.93
403_A 498_I 1.804 0.93
54_F 88_T 1.797 0.93
463_A 499_V 1.791 0.92
86_A 170_L 1.768 0.92
79_L 91_A 1.766 0.92
223_I 249_S 1.761 0.92
178_Y 182_V 1.752 0.91
250_F 399_M 1.748 0.91
318_F 322_V 1.722 0.90
580_D 585_R 1.705 0.90
256_G 283_A 1.7 0.90
125_V 190_F 1.666 0.88
3_P 68_V 1.654 0.88
129_M 189_A 1.65 0.88
70_Y 79_L 1.65 0.88
529_T 551_T 1.623 0.86
76_N 79_L 1.619 0.86
47_F 105_G 1.6 0.85
54_F 58_V 1.599 0.85
548_I 602_V 1.597 0.85
520_S 529_T 1.591 0.85
54_F 101_L 1.586 0.85
372_L 390_F 1.564 0.84
291_T 315_I 1.555 0.83
362_A 395_F 1.546 0.83
522_D 525_E 1.52 0.81
160_D 570_A 1.518 0.81
522_D 527_R 1.517 0.81
377_K 383_S 1.515 0.81
564_K 575_T 1.514 0.81
515_M 520_S 1.512 0.81
228_A 586_D 1.507 0.80
528_F 548_I 1.497 0.80
463_A 492_L 1.495 0.80
434_L 463_A 1.494 0.79
255_V 363_M 1.492 0.79
547_T 559_V 1.488 0.79
275_W 356_N 1.481 0.79
504_S 617_G 1.479 0.79
372_L 376_H 1.468 0.78
181_Y 294_V 1.458 0.77
259_L 280_A 1.452 0.77
315_I 319_M 1.43 0.75
524_H 606_Y 1.424 0.75
393_T 397_W 1.419 0.74
413_R 417_D 1.403 0.73
60_A 63_V 1.394 0.73
283_A 286_L 1.39 0.72
439_L 517_S 1.389 0.72
176_L 221_L 1.386 0.72
127_A 131_M 1.38 0.71
87_A 171_I 1.375 0.71
543_G 563_E 1.368 0.71
9_L 52_G 1.366 0.70
178_Y 275_W 1.362 0.70
25_L 127_A 1.358 0.70
58_V 62_V 1.352 0.69
14_L 137_L 1.352 0.69
3_P 60_A 1.338 0.68
128_I 192_I 1.333 0.68
459_A 495_A 1.329 0.67
565_R 576_E 1.329 0.67
12_L 359_L 1.327 0.67
504_S 508_S 1.322 0.67
239_W 487_M 1.317 0.66
304_A 523_I 1.315 0.66
44_W 111_A 1.312 0.66
61_F 70_Y 1.301 0.65
546_A 602_V 1.289 0.64
70_Y 76_N 1.285 0.63
486_G 623_G 1.273 0.62
87_A 91_A 1.268 0.62
332_A 335_H 1.266 0.62
489_A 550_V 1.262 0.61
217_I 624_G 1.261 0.61
78_Q 157_E 1.261 0.61
64_N 70_Y 1.258 0.61
213_L 260_M 1.25 0.60
528_F 589_A 1.249 0.60
262_S 275_W 1.247 0.60
402_F 469_E 1.246 0.60
96_L 230_A 1.233 0.59
75_S 93_E 1.226 0.58
224_V 504_S 1.221 0.58
227_S 241_F 1.215 0.57
403_A 587_L 1.214 0.57
283_A 403_A 1.213 0.57
392_N 617_G 1.21 0.57
332_A 392_N 1.21 0.57
464_V 467_I 1.206 0.56
496_V 619_M 1.205 0.56
220_T 620_M 1.203 0.56
266_T 276_T 1.198 0.55
494_L 588_Y 1.197 0.55
168_P 172_F 1.194 0.55
267_E 273_K 1.188 0.55
582_G 585_R 1.185 0.54
377_K 381_L 1.183 0.54
74_N 90_G 1.181 0.54
365_V 378_Q 1.18 0.54
315_I 324_G 1.18 0.54
583_I 615_A 1.178 0.54
47_F 108_F 1.177 0.53
20_L 130_G 1.177 0.53
213_L 627_C 1.174 0.53
66_F 77_T 1.174 0.53
529_T 549_G 1.173 0.53
622_L 625_L 1.169 0.53
397_W 401_P 1.168 0.53
262_S 355_N 1.167 0.53
171_I 574_M 1.167 0.53
289_L 367_L 1.164 0.52
536_V 545_V 1.162 0.52
17_A 46_L 1.161 0.52
53_A 357_V 1.161 0.52
9_L 49_S 1.159 0.52
168_P 318_F 1.153 0.51
61_F 87_A 1.153 0.51
104_S 434_L 1.148 0.51
251_M 283_A 1.147 0.51
532_D 546_A 1.147 0.51
435_V 464_V 1.146 0.50
8_G 11_C 1.142 0.50
534_K 547_T 1.142 0.50
47_F 390_F 1.139 0.50
289_L 371_L 1.138 0.50
43_A 46_L 1.137 0.50
47_F 51_A 1.137 0.50
54_F 91_A 1.133 0.49
230_A 241_F 1.131 0.49
514_R 595_L 1.126 0.49
255_V 286_L 1.125 0.48
60_A 68_V 1.124 0.48
5_I 52_G 1.123 0.48
74_N 93_E 1.114 0.47
129_M 185_S 1.112 0.47
223_I 565_R 1.109 0.47
403_A 406_L 1.107 0.47
192_I 326_S 1.106 0.47
251_M 255_V 1.105 0.47
375_V 489_A 1.105 0.47
45_L 550_V 1.102 0.46
247_N 370_T 1.102 0.46
412_V 417_D 1.101 0.46
76_N 87_A 1.1 0.46
157_E 321_L 1.1 0.46
128_I 329_L 1.097 0.46
157_E 569_T 1.097 0.46
292_F 316_L 1.097 0.46
92_H 241_F 1.095 0.46
61_F 75_S 1.094 0.46
7_N 11_C 1.094 0.46
540_N 565_R 1.094 0.46
452_T 527_R 1.092 0.45
501_I 573_M 1.092 0.45
520_S 527_R 1.092 0.45
20_L 42_F 1.092 0.45
269_R 349_E 1.091 0.45
164_L 600_W 1.091 0.45
104_S 523_I 1.088 0.45
611_R 617_G 1.086 0.45
170_L 232_Y 1.084 0.45
91_A 171_I 1.082 0.44
497_T 501_I 1.079 0.44
30_R 37_A 1.076 0.44
70_Y 96_L 1.074 0.44
82_W 171_I 1.074 0.44
376_H 384_I 1.073 0.44
551_T 556_P 1.073 0.44
167_D 232_Y 1.071 0.43
267_E 356_N 1.07 0.43
527_R 554_G 1.065 0.43
223_I 540_N 1.065 0.43
86_A 307_S 1.063 0.43
50_V 104_S 1.062 0.42
98_L 293_L 1.062 0.42
549_G 556_P 1.061 0.42
407_G 495_A 1.06 0.42
72_A 150_T 1.06 0.42
43_A 107_T 1.06 0.42
510_E 605_Y 1.057 0.42
372_L 386_I 1.056 0.42
365_V 394_M 1.055 0.42
143_T 575_T 1.052 0.42
263_L 352_L 1.051 0.41
58_V 85_V 1.049 0.41
160_D 590_A 1.049 0.41
317_A 321_L 1.048 0.41
176_L 604_L 1.046 0.41
500_G 616_G 1.046 0.41
170_L 405_L 1.045 0.41
55_L 260_M 1.044 0.41
502_A 505_Q 1.041 0.41
4_E 149_R 1.039 0.40
85_V 459_A 1.037 0.40
75_S 84_R 1.035 0.40
92_H 311_R 1.034 0.40
546_A 575_T 1.033 0.40
169_G 294_V 1.032 0.40
14_L 134_V 1.031 0.40
408_V 520_S 1.03 0.40
390_F 501_I 1.03 0.40
233_E 574_M 1.028 0.39
157_E 596_E 1.028 0.39
550_V 560_L 1.027 0.39
178_Y 540_N 1.025 0.39
269_R 356_N 1.023 0.39
190_F 348_R 1.022 0.39
76_N 129_M 1.022 0.39
25_L 464_V 1.021 0.39
343_N 386_I 1.021 0.39
110_V 190_F 1.02 0.39
332_A 497_T 1.019 0.39
16_I 543_G 1.017 0.38
152_P 272_F 1.017 0.38
262_S 290_G 1.015 0.38
44_W 108_F 1.015 0.38
17_A 438_L 1.015 0.38
466_A 495_A 1.013 0.38
203_T 304_A 1.013 0.38
586_D 612_W 1.013 0.38
265_V 355_N 1.012 0.38
333_R 415_G 1.012 0.38
250_F 334_G 1.011 0.38
76_N 91_A 1.011 0.38
170_L 606_Y 1.011 0.38
102_L 122_V 1.01 0.38
167_D 294_V 1.008 0.38
90_G 308_D 1.008 0.38
28_V 36_M 1.007 0.37
61_F 91_A 1.007 0.37
436_L 555_K 1.007 0.37
275_W 349_E 1.007 0.37
508_S 607_K 1.005 0.37
474_I 602_V 1.004 0.37
473_R 631_P 1.003 0.37
262_S 276_T 1.002 0.37
75_S 92_H 1.001 0.37
523_I 528_F 1.001 0.37
11_C 15_G 1 0.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2l97A10.176210.40.988Contact Map0.284
3cfuA20.16699.70.988Contact Map0.549
2eaqA10.12984.70.99Contact Map0.275
2zpmA10.1364.40.99Contact Map0.268
3qbgA30.10514.30.99Contact Map0
2cfqA10.58584.10.99Contact Map0.099
1q90R10.07573.70.99Contact Map0
3mcbA10.08353.60.99Contact Map0.25
3wdoA10.6263.60.99Contact Map0.118
2kpkA10.17933.60.99Contact Map0.317

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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