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CSPB - Cold shock-like protein CspB
UniProt: P36995 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12203
Length: 71 (67)
Sequences: 3009
Seq/Len: 44.91

CSPB
Paralog alert: 0.78 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: CSPA CSPB CSPC CSPD CSPE CSPF CSPG CSPH CSPI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
56_E 65_A 3.944 1.00
32_V 67_V 3.852 1.00
54_S 66_N 2.889 1.00
49_Q 69_I 2.454 1.00
8_L 50_K 2.274 1.00
24_V 50_K 2.186 1.00
14_A 46_F 2.138 1.00
52_T 68_I 2.04 1.00
6_T 52_T 2.018 1.00
52_T 70_T 1.909 1.00
6_T 50_K 1.784 1.00
38_Q 66_N 1.782 1.00
36_A 65_A 1.754 1.00
5_M 23_P 1.7 1.00
23_P 53_F 1.645 1.00
23_P 26_G 1.623 1.00
23_P 27_S 1.588 1.00
58_G 63_A 1.585 1.00
64_A 67_V 1.54 1.00
57_S 62_P 1.535 1.00
32_V 45_L 1.519 1.00
38_Q 68_I 1.4 0.99
14_A 44_T 1.365 0.99
12_F 34_F 1.29 0.99
23_P 28_K 1.266 0.99
34_F 37_I 1.253 0.99
50_K 70_T 1.179 0.98
14_A 42_Y 1.176 0.98
39_N 69_I 1.175 0.98
6_T 24_V 1.175 0.98
46_F 49_Q 1.148 0.97
8_L 22_S 1.116 0.96
36_A 56_E 1.061 0.95
34_F 43_R 1.046 0.94
30_V 55_I 1.011 0.93
55_I 62_P 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2lssA10.985999.90.119Contact Map0.603
3camA20.943799.90.124Contact Map0.855
3i2zB20.985999.90.133Contact Map0.901
1h95A1199.90.138Contact Map0.572
2lxjA10.929699.90.146Contact Map0.551
1c9oA20.929699.90.146Contact Map0.863
1g6pA10.929699.80.151Contact Map0.49
3a0jA20.943799.80.155Contact Map0.823
2kcmA10.929699.80.161Contact Map0.499
3uljA2199.80.173Contact Map0.785

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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