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CRCB - Protein CrcB
UniProt: P37002 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12209
Length: 127 (121)
Sequences: 2082
Seq/Len: 17.21

CRCB
Paralog alert: 0.35 [within 20: 0.24] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
43_I 77_L 4.818 1.00
44_G 78_T 4.78 1.00
12_G 16_S 3.191 1.00
48_I 70_T 3.023 1.00
42_L 113_M 3.004 1.00
9_F 13_G 2.898 1.00
42_L 109_G 2.722 1.00
102_N 106_N 2.675 1.00
11_G 68_L 2.406 1.00
18_A 73_F 2.35 1.00
13_G 76_G 2.261 1.00
40_A 77_L 1.952 1.00
14_T 73_F 1.939 1.00
87_V 102_N 1.899 1.00
14_T 68_L 1.839 1.00
45_A 110_S 1.713 1.00
87_V 99_A 1.702 1.00
22_L 40_A 1.673 1.00
16_S 76_G 1.652 1.00
50_I 121_F 1.648 1.00
48_I 76_G 1.605 1.00
47_I 74_C 1.599 1.00
37_T 86_E 1.577 1.00
20_W 24_M 1.563 1.00
87_V 103_V 1.483 1.00
46_F 120_L 1.481 1.00
48_I 74_C 1.474 1.00
48_I 114_T 1.472 1.00
38_L 105_V 1.419 1.00
38_L 42_L 1.415 1.00
36_G 40_A 1.412 1.00
51_G 69_I 1.354 0.99
46_F 117_A 1.35 0.99
51_G 70_T 1.343 0.99
17_V 21_L 1.294 0.99
68_L 73_F 1.271 0.99
53_A 118_F 1.239 0.98
117_A 121_F 1.227 0.98
53_A 57_R 1.223 0.98
82_T 86_E 1.179 0.98
65_W 69_I 1.165 0.97
46_F 53_A 1.132 0.97
100_L 104_F 1.127 0.97
46_F 113_M 1.115 0.96
91_L 99_A 1.114 0.96
115_A 119_W 1.096 0.96
33_I 38_L 1.056 0.95
89_F 92_Q 1.041 0.94
21_L 24_M 1.035 0.94
10_I 13_G 1.016 0.93
83_F 103_V 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4ldsA20.92911.60.948Contact Map0.119
2kv5A10.2521.40.949Contact Map0.4
3iyzA10.79531.30.95Contact Map0
4apsA20.95281.30.95Contact Map0.074
4gc0A10.96851.20.951Contact Map0.09
4j05A20.96061.20.952Contact Map0.123
3o0rB10.34651.10.952Contact Map0.219
4b19A10.23621.10.953Contact Map0.656
3hzqA10.519710.954Contact Map0.221
3orgA40.574810.954Contact Map0.2

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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