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YJJW - Uncharacterized protein YjjW
UniProt: P39409 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12599
Length: 287 (274)
Sequences: 1313
Seq/Len: 4.79

YJJW
Paralog alert: 0.50 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: NRDG PFLA PFLC PFLE YJJW
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
118_V 130_V 3.862 1.00
116_I 137_I 3.565 1.00
180_S 190_D 3.409 1.00
99_V 136_A 2.961 1.00
107_R 140_D 2.792 1.00
100_D 136_A 2.698 1.00
180_S 192_Q 2.661 1.00
135_T 167_V 2.618 1.00
136_A 139_N 2.597 1.00
183_H 191_N 2.549 1.00
8_V 28_L 2.449 1.00
173_L 198_I 2.412 1.00
222_L 267_P 2.382 1.00
147_T 170_G 2.333 1.00
32_N 153_N 2.265 1.00
154_G 173_L 2.221 1.00
138_K 169_D 2.189 1.00
182_C 185_Q 2.088 1.00
212_L 240_V 2.067 1.00
9_S 43_T 2.012 1.00
134_F 148_C 1.99 1.00
135_T 163_K 1.932 1.00
106_V 137_I 1.931 1.00
76_C 79_C 1.896 1.00
210_L 232_I 1.86 1.00
103_L 137_I 1.858 1.00
118_V 133_L 1.833 1.00
260_A 265_V 1.791 1.00
79_C 82_C 1.789 1.00
269_A 273_K 1.788 1.00
179_G 227_E 1.773 1.00
105_H 108_K 1.761 1.00
230_A 275_R 1.753 1.00
37_N 215_I 1.726 1.00
264_D 267_P 1.714 1.00
200_L 204_R 1.713 0.99
76_C 82_C 1.693 0.99
162_E 200_L 1.692 0.99
136_A 140_D 1.657 0.99
182_C 224_H 1.632 0.99
100_D 104_S 1.594 0.99
226_E 274_V 1.576 0.99
222_L 264_D 1.571 0.99
220_D 264_D 1.563 0.99
24_L 105_H 1.549 0.99
198_I 231_F 1.547 0.99
6_A 126_Q 1.543 0.99
97_M 102_V 1.536 0.99
39_H 151_D 1.526 0.99
6_A 129_F 1.524 0.99
192_Q 196_R 1.516 0.98
221_Y 224_H 1.511 0.98
222_L 226_E 1.505 0.98
118_V 134_F 1.498 0.98
199_Y 234_G 1.485 0.98
123_A 130_V 1.485 0.98
12_I 15_S 1.469 0.98
150_V 171_A 1.466 0.98
98_S 101_E 1.442 0.98
227_E 230_A 1.417 0.97
232_I 240_V 1.416 0.97
158_E 200_L 1.4 0.97
32_N 125_T 1.399 0.97
225_I 268_L 1.397 0.97
131_V 163_K 1.393 0.97
261_T 264_D 1.385 0.97
178_W 231_F 1.378 0.97
208_A 237_D 1.375 0.97
207_L 238_V 1.355 0.96
266_E 269_A 1.352 0.96
214_V 265_V 1.343 0.96
183_H 245_F 1.336 0.96
226_E 271_A 1.329 0.96
229_A 272_L 1.321 0.96
270_D 274_V 1.301 0.95
183_H 194_I 1.289 0.95
214_V 242_L 1.278 0.94
36_K 185_Q 1.274 0.94
223_Q 227_E 1.274 0.94
99_V 133_L 1.246 0.93
226_E 275_R 1.234 0.93
184_Q 190_D 1.233 0.93
196_R 199_Y 1.227 0.93
134_F 168_C 1.225 0.93
103_L 136_A 1.207 0.92
266_E 270_D 1.206 0.92
162_E 204_R 1.201 0.92
102_V 133_L 1.191 0.91
97_M 101_E 1.191 0.91
123_A 150_V 1.185 0.91
177_A 224_H 1.177 0.91
33_L 194_I 1.17 0.90
229_A 271_A 1.166 0.90
202_A 236_G 1.158 0.90
95_Q 105_H 1.147 0.89
171_A 206_K 1.14 0.89
7_L 96_S 1.137 0.88
186_L 218_Q 1.12 0.87
209_E 239_P 1.12 0.87
262_P 266_E 1.113 0.87
26_L 106_V 1.109 0.87
107_R 110_V 1.101 0.86
106_V 116_I 1.1 0.86
138_K 167_V 1.097 0.86
171_A 201_L 1.096 0.86
124_T 164_L 1.093 0.86
28_L 118_V 1.092 0.86
199_Y 203_E 1.09 0.85
151_D 209_E 1.088 0.85
23_R 117_T 1.086 0.85
154_G 197_S 1.085 0.85
214_V 268_L 1.081 0.85
171_A 198_I 1.076 0.84
240_V 272_L 1.061 0.83
178_W 227_E 1.053 0.83
151_D 154_G 1.038 0.81
8_V 97_M 1.029 0.81
178_W 224_H 1.028 0.81
158_E 162_E 1.028 0.81
24_L 109_A 1.027 0.81
246_H 249_G 1.025 0.80
199_Y 231_F 1.021 0.80
19_G 23_R 1.019 0.80
36_K 186_L 1.018 0.80
168_C 171_A 1.017 0.80
181_E 184_Q 1.016 0.80
191_N 194_I 1.015 0.79
50_C 53_C 1.014 0.79
99_V 132_A 1.011 0.79
19_G 117_T 1.01 0.79
57_C 79_C 1.008 0.79
212_L 228_L 1.007 0.79
195_K 231_F 1.002 0.78
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3c8fA10.80141000.56Contact Map0.779
3canA10.59231000.689Contact Map0.77
3rfaA20.7841000.704Contact Map0.641
2yx0A10.82581000.711Contact Map0.704
1hfeL20.86411000.713Contact Map0.123
2z2uA10.825899.90.721Contact Map0.662
1tv8A20.797999.90.745Contact Map0.762
1oltA10.843299.90.751Contact Map0.465
2qgqA80.756199.90.762Contact Map0.696
1q16B10.773599.90.772Contact Map0.094

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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