GREMLIN.BAKERLAB.org
Powered by OPENSEQ.org
YCBF - Uncharacterized fimbrial chaperone YcbF
UniProt: P40876 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12397
Length: 236 (208)
Sequences: 1348
Seq/Len: 6.48

YCBF
Paralog alert: 0.90 [within 20: 0.51] - ratio of genomes with paralogs
Cluster includes: ECPD ELFD FIMC SFMC YBGP YCBF YEHC YFCS YHCA YQIH YRAI
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
107_L 115_F 2.958 1.00
30_V 140_F 2.906 1.00
180_N 196_V 2.898 1.00
178_Y 198_P 2.71 1.00
198_P 201_S 2.684 1.00
114_L 196_V 2.683 1.00
143_F 196_V 2.511 1.00
38_P 41_R 2.483 1.00
111_R 200_K 2.448 1.00
172_T 202_Q 2.397 1.00
35_F 117_L 2.279 1.00
161_R 172_T 2.183 1.00
56_W 121_S 2.18 1.00
62_I 142_L 2.164 1.00
35_F 44_I 2.135 1.00
61_K 118_S 2.129 1.00
171_L 205_T 2.103 1.00
63_N 139_V 2.076 1.00
108_P 113_T 2.07 1.00
55_S 88_L 1.972 1.00
35_F 99_L 1.968 1.00
55_S 90_K 1.951 1.00
39_A 109_V 1.951 1.00
118_S 139_V 1.871 1.00
120_A 137_R 1.761 1.00
80_L 99_L 1.666 1.00
63_N 118_S 1.665 1.00
114_L 180_N 1.631 1.00
40_D 147_E 1.627 1.00
149_L 177_Y 1.607 1.00
162_W 171_L 1.582 1.00
108_P 111_R 1.577 0.99
159_Q 175_T 1.556 0.99
153_P 156_A 1.548 0.99
90_K 93_T 1.545 0.99
101_R 104_S 1.54 0.99
28_V 89_L 1.537 0.99
170_Q 204_Q 1.533 0.99
222_N 228_S 1.503 0.99
99_L 142_L 1.487 0.99
82_A 97_L 1.473 0.99
165_N 170_Q 1.442 0.99
157_Y 218_W 1.438 0.99
30_V 119_I 1.431 0.99
170_Q 202_Q 1.4 0.99
155_E 158_Q 1.38 0.98
222_N 226_G 1.374 0.98
47_L 94_T 1.37 0.98
156_A 179_I 1.364 0.98
163_T 170_Q 1.352 0.98
35_F 140_F 1.344 0.98
180_N 220_A 1.339 0.98
160_L 171_L 1.336 0.98
38_P 44_I 1.328 0.98
197_V 203_R 1.319 0.98
63_N 116_E 1.317 0.98
179_I 220_A 1.307 0.97
48_L 58_I 1.303 0.97
29_V 32_G 1.29 0.97
143_F 178_Y 1.288 0.97
58_I 87_I 1.257 0.96
53_Q 92_G 1.234 0.96
156_A 220_A 1.234 0.96
97_L 117_L 1.225 0.96
60_S 119_I 1.223 0.96
197_V 201_S 1.218 0.96
114_L 143_F 1.218 0.96
30_V 46_I 1.216 0.96
37_F 44_I 1.202 0.95
165_N 168_G 1.202 0.95
95_G 120_A 1.187 0.95
27_G 121_S 1.185 0.95
162_W 184_V 1.178 0.94
101_R 144_W 1.175 0.94
122_V 136_M 1.175 0.94
163_T 172_T 1.171 0.94
55_S 124_S 1.159 0.94
116_E 120_A 1.137 0.93
82_A 99_L 1.136 0.93
82_A 117_L 1.134 0.93
168_G 204_Q 1.118 0.92
181_L 197_V 1.115 0.92
97_L 119_I 1.111 0.92
151_G 155_E 1.096 0.91
220_A 228_S 1.085 0.91
96_T 137_R 1.082 0.90
153_P 157_Y 1.074 0.90
95_G 121_S 1.046 0.88
60_S 97_L 1.044 0.88
56_W 120_A 1.035 0.88
171_L 181_L 1.034 0.88
76_V 79_P 1.03 0.87
112_E 145_R 1.027 0.87
57_L 177_Y 1.026 0.87
52_S 56_W 1.026 0.87
89_L 94_T 1.026 0.87
183_Q 219_R 1.024 0.87
48_L 89_L 1.017 0.86
52_S 121_S 1.007 0.86
61_K 139_V 1.005 0.85
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4djmA80.94491000.203Contact Map0.815
1klfA80.85171000.216Contact Map0.792
2co7B10.90251000.218Contact Map0.738
4ay0A20.9111000.221Contact Map0.759
1l4iA20.85591000.222Contact Map0.775
2xg5A10.85171000.244Contact Map0.801
3gfuC20.82631000.249Contact Map0.713
3q48A20.96191000.269Contact Map0.808
1mspA20.474659.30.947Contact Map0.54
1z9lA10.483131.80.955Contact Map0.685

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.025 seconds.