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AAEX - Protein AaeX
UniProt: P46478 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12824
Length: 67 (63)
Sequences: 253
Seq/Len: 4.02

AAEX
Paralog alert: 0.11 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
45_W 50_F 2.454 1.00
44_V 50_F 2.355 1.00
35_L 40_I 2.125 1.00
33_R 37_P 1.687 0.99
5_P 57_C 1.641 0.99
26_A 31_V 1.469 0.97
52_T 56_C 1.415 0.96
21_L 55_Y 1.408 0.96
4_F 57_C 1.374 0.95
17_I 48_A 1.371 0.95
55_Y 59_F 1.371 0.95
49_L 53_A 1.361 0.95
46_H 49_L 1.348 0.95
32_R 51_N 1.313 0.94
11_G 24_S 1.298 0.93
41_Y 51_N 1.292 0.93
4_F 32_R 1.289 0.93
31_V 58_L 1.289 0.93
40_I 44_V 1.267 0.92
47_P 60_Y 1.256 0.92
24_S 59_F 1.235 0.91
32_R 55_Y 1.171 0.87
21_L 51_N 1.123 0.84
31_V 34_V 1.082 0.81
39_G 50_F 1.069 0.80
14_F 54_L 1.053 0.78
16_P 48_A 1.053 0.78
53_A 62_I 1.037 0.77
15_P 60_Y 1.031 0.76
31_V 49_L 1.007 0.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4dveA30.62694.60.903Contact Map0.156
3tx3A20.7912.60.914Contact Map0.135
3wguB20.58212.20.918Contact Map0.071
4hytB20.58212.20.918Contact Map0.099
3nd0A211.80.921Contact Map0.065
4eneA20.98511.60.923Contact Map0.114
1fftA20.97011.30.927Contact Map0.232
2kseA10.49251.30.928Contact Map0
3ua0A20.38811.20.93Contact Map
2zxeB10.5971.20.93Contact Map0.281

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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