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CBPM - Chaperone modulatory protein CbpM
UniProt: P63264 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12194
Length: 101 (100)
Sequences: 153
Seq/Len: 1.53

CBPM
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
56_A 70_I 2.319 0.99
63_L 69_G 1.737 0.95
86_E 90_L 1.692 0.93
14_C 63_L 1.617 0.91
35_P 63_L 1.539 0.88
14_C 35_P 1.472 0.85
80_I 84_K 1.436 0.83
37_E 40_E 1.419 0.82
56_A 74_L 1.404 0.81
36_R 72_V 1.387 0.80
66_D 69_G 1.385 0.80
79_D 92_Q 1.372 0.79
69_G 73_A 1.352 0.78
12_E 15_L 1.312 0.75
37_E 72_V 1.3 0.74
24_L 33_V 1.291 0.73
46_D 49_A 1.29 0.73
18_G 58_R 1.246 0.69
16_H 53_V 1.243 0.69
69_G 74_L 1.238 0.68
27_I 67_W 1.226 0.67
2_A 99_A 1.207 0.66
27_I 60_R 1.185 0.63
22_E 28_V 1.18 0.63
50_A 80_I 1.179 0.63
22_E 88_R 1.17 0.62
3_N 95_S 1.169 0.62
14_C 69_G 1.168 0.62
86_E 91_R 1.163 0.61
55_R 65_L 1.152 0.60
17_T 52_V 1.152 0.60
37_E 44_V 1.126 0.58
27_I 32_V 1.123 0.57
39_Q 51_I 1.11 0.56
67_W 87_N 1.105 0.55
8_F 53_V 1.081 0.53
9_T 81_A 1.077 0.53
87_N 96_R 1.075 0.52
25_N 81_A 1.072 0.52
27_I 68_P 1.07 0.52
14_C 65_L 1.061 0.51
9_T 80_I 1.055 0.50
8_F 54_Q 1.05 0.50
28_V 43_W 1.05 0.50
27_I 69_G 1.038 0.49
30_L 53_V 1.037 0.48
33_V 53_V 1.028 0.47
50_A 57_V 1.022 0.47
1_M 5_T 1.022 0.47
27_I 55_R 1.017 0.46
14_C 55_R 1.014 0.46
32_V 38_I 1.014 0.46
52_V 95_S 1.001 0.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ucsA2199.50.575Contact Map0.268
1r8dA20.940697.90.76Contact Map0.319
2vz4A10.930797.80.766Contact Map0.283
3gpvA20.990197.70.771Contact Map0.295
2zhgA10.990197.60.775Contact Map0.262
3gp4A20.940697.30.786Contact Map0.249
3qaoA10.950597.20.787Contact Map0.318
2jmlA10.782297.20.79Contact Map0.301
1q06A20.920897.10.791Contact Map0.287
1r8eA10.970397.10.791Contact Map0.302

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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