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ATPL - ATP synthase subunit c
UniProt: P68699 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10102
Length: 79 (73)
Sequences: 835
Seq/Len: 11.44

ATPL
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
34_K 37_E 4.23 1.00
32_G 56_V 3.376 1.00
35_F 49_L 2.548 1.00
46_I 50_R 2.111 1.00
32_G 57_M 1.778 1.00
26_I 30_I 1.751 1.00
39_A 45_L 1.695 1.00
39_A 52_Q 1.638 1.00
72_L 76_F 1.619 1.00
23_G 29_G 1.563 1.00
45_L 49_L 1.497 1.00
39_A 46_I 1.482 1.00
23_G 26_I 1.448 1.00
24_A 64_P 1.441 1.00
28_I 62_A 1.42 1.00
55_I 59_L 1.402 0.99
30_I 34_K 1.393 0.99
28_I 63_I 1.258 0.99
28_I 60_V 1.248 0.99
8_L 11_M 1.234 0.98
10_Y 78_V 1.21 0.98
17_M 67_A 1.19 0.98
53_F 57_M 1.17 0.97
62_A 65_M 1.142 0.97
46_I 51_T 1.138 0.97
24_A 28_I 1.129 0.97
57_M 63_I 1.121 0.97
35_F 53_F 1.08 0.95
31_L 60_V 1.069 0.95
23_G 27_G 1.064 0.95
22_I 42_Q 1.054 0.95
63_I 68_V 1.044 0.94
69_G 72_L 1.042 0.94
30_I 33_G 1.04 0.94
41_R 44_D 1.028 0.94
36_L 52_Q 1.013 0.93
9_L 78_V 1.011 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1a91A1199.80.167Contact Map0.236
2xquA5199.70.212Contact Map0.731
3zk1A220.987399.70.235Contact Map0.747
1wu0A10.911499.70.27Contact Map0.277
2x2vA130.873499.70.27Contact Map0.756
4f4sA100.96299.60.28Contact Map0.722
2xndJ80.911499.60.3Contact Map0.423
2bl2A100.936799.40.37Contact Map0.567
4g1uA20.89871.70.925Contact Map0.288
2l16A10.32911.60.926Contact Map0.126

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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