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CSRA - Carbon storage regulator
UniProt: P69913 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11447
Length: 61 (58)
Sequences: 511
Seq/Len: 8.81

CSRA
Paralog alert: 0.06 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
43_H 47_I 2.859 1.00
19_T 45_E 2.252 1.00
43_H 51_I 2.245 1.00
19_T 35_N 2.202 1.00
28_N 50_R 1.955 1.00
43_H 48_Y 1.792 1.00
7_R 10_E 1.759 1.00
11_T 19_T 1.707 1.00
9_G 12_L 1.7 1.00
55_K 58_Q 1.685 1.00
4_L 27_G 1.528 1.00
26_K 31_R 1.44 0.99
9_G 23_L 1.38 0.99
48_Y 51_I 1.335 0.99
45_E 49_Q 1.305 0.99
3_I 26_K 1.215 0.98
34_V 42_V 1.193 0.97
4_L 33_G 1.185 0.97
5_T 9_G 1.165 0.97
17_E 39_E 1.162 0.97
49_Q 53_A 1.14 0.96
18_V 30_V 1.085 0.94
11_T 21_T 1.076 0.94
12_L 34_V 1.05 0.93
25_V 30_V 1.025 0.92
22_V 32_I 1.017 0.92
8_V 34_V 1.008 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2btiA2199.90.029Contact Map0.588
1t3oA1199.90.038Contact Map0.362
1vpzA2199.90.052Contact Map0.585
2jppA2199.90.052Contact Map0.62
4krwA10.868999.80.162Contact Map0.41
2vnuD10.606651.70.842Contact Map0.056
4ifdJ10.606650.50.844Contact Map0.08
1go3E20.885236.80.856Contact Map0.158
2id0A40.590233.50.859Contact Map0.399
4aidA30.901622.90.87Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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