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SSUC - Putative aliphatic sulfonates transport permease protein SsuC
UniProt: P75851 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13705
Length: 263 (245)
Sequences: 5071
Seq/Len: 20.70

SSUC
Paralog alert: 0.71 [within 20: 0.24] - ratio of genomes with paralogs
Cluster includes: ARTM ARTQ GLNP GLTJ GLTK HISM HISQ METI PHNE SSUC TAUC YECS YEHW
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
26_Q 30_S 4.349 1.00
26_Q 43_E 3.053 1.00
94_E 148_R 2.942 1.00
49_F 226_V 2.893 1.00
158_A 172_V 2.87 1.00
164_S 167_P 2.786 1.00
75_I 132_A 2.66 1.00
166_I 170_I 2.55 1.00
116_V 129_F 2.512 1.00
67_W 71_I 2.384 1.00
63_A 67_W 2.357 1.00
68_R 124_E 2.326 1.00
146_G 180_S 2.312 1.00
120_F 129_F 2.254 1.00
65_S 196_L 2.251 1.00
220_Q 223_V 2.233 1.00
212_A 227_A 2.132 1.00
79_L 132_A 2.028 1.00
46_V 50_W 1.996 1.00
76_G 135_T 1.928 1.00
77_G 185_V 1.915 1.00
61_H 211_L 1.87 1.00
79_L 136_L 1.864 1.00
158_A 163_L 1.848 1.00
143_T 181_I 1.839 1.00
28_A 33_W 1.831 1.00
248_L 251_R 1.802 1.00
84_G 88_G 1.795 1.00
79_L 82_I 1.793 1.00
50_W 54_A 1.792 1.00
87_S 140_Y 1.737 1.00
71_I 128_I 1.694 1.00
91_R 94_E 1.693 1.00
125_S 129_F 1.69 1.00
215_A 223_V 1.683 1.00
136_L 140_Y 1.668 1.00
244_L 247_R 1.663 1.00
139_I 188_A 1.656 1.00
167_P 171_H 1.635 1.00
244_L 248_L 1.632 1.00
177_A 181_I 1.632 1.00
44_G 47_T 1.614 1.00
165_G 168_L 1.595 1.00
80_G 139_I 1.588 1.00
76_G 132_A 1.569 1.00
80_G 140_Y 1.567 1.00
241_S 245_L 1.56 1.00
53_S 59_W 1.556 1.00
91_R 95_R 1.543 1.00
43_E 47_T 1.521 1.00
84_G 147_I 1.514 1.00
47_T 51_T 1.501 1.00
147_I 173_I 1.484 1.00
150_I 176_G 1.481 1.00
240_V 244_L 1.476 1.00
93_G 97_L 1.451 1.00
27_L 31_V 1.433 1.00
23_A 27_L 1.417 1.00
29_S 41_S 1.394 0.99
88_G 147_I 1.39 0.99
211_L 227_A 1.389 0.99
157_M 161_Y 1.387 0.99
155_V 168_L 1.346 0.99
78_S 82_I 1.346 0.99
41_S 44_G 1.331 0.99
186_R 246_E 1.319 0.99
87_S 144_W 1.316 0.99
90_S 93_G 1.292 0.99
48_A 220_Q 1.286 0.99
59_W 63_A 1.286 0.99
64_I 206_S 1.281 0.99
64_I 68_R 1.278 0.99
66_S 234_L 1.263 0.99
72_G 131_V 1.258 0.99
159_R 168_L 1.256 0.99
146_G 184_G 1.253 0.99
83_L 140_Y 1.246 0.98
116_V 126_A 1.24 0.98
116_V 120_F 1.221 0.98
30_S 43_E 1.22 0.98
73_F 185_V 1.219 0.98
156_E 159_R 1.212 0.98
186_R 239_D 1.208 0.98
36_T 44_G 1.207 0.98
62_L 234_L 1.188 0.98
213_M 216_R 1.181 0.98
87_S 93_G 1.173 0.98
116_V 133_L 1.169 0.97
80_G 84_G 1.166 0.97
83_L 136_L 1.158 0.97
73_F 77_G 1.155 0.97
167_P 170_I 1.146 0.97
102_Q 105_R 1.146 0.97
77_G 81_L 1.135 0.97
157_M 162_G 1.132 0.97
48_A 51_T 1.13 0.97
26_Q 41_S 1.107 0.96
48_A 222_D 1.092 0.96
163_L 168_L 1.09 0.96
240_V 243_Q 1.086 0.96
237_L 241_S 1.079 0.95
245_L 249_W 1.077 0.95
153_G 156_E 1.074 0.95
89_L 92_W 1.072 0.95
151_D 154_L 1.069 0.95
72_G 76_G 1.068 0.95
62_L 208_I 1.065 0.95
134_G 195_T 1.064 0.95
110_L 198_V 1.061 0.95
70_L 74_S 1.059 0.95
81_L 181_I 1.059 0.95
84_G 143_T 1.058 0.95
154_L 157_M 1.052 0.95
86_I 93_G 1.049 0.94
87_S 97_L 1.04 0.94
80_G 143_T 1.039 0.94
197_I 231_Y 1.033 0.94
60_Q 206_S 1.031 0.94
215_A 224_V 1.029 0.94
89_L 165_G 1.027 0.94
138_P 191_L 1.022 0.93
142_N 183_V 1.015 0.93
184_G 188_A 1.013 0.93
163_L 167_P 1.005 0.93
26_Q 29_S 1.005 0.93
142_N 146_G 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3d31C20.954499.90.58Contact Map0.583
3rlfF10.950699.90.603Contact Map0.663
2onkC40.950699.90.609Contact Map0.652
3tuiA40.768199.90.616Contact Map0.761
3rlfG10.969699.80.659Contact Map0.559
3veaB20.28522.50.968Contact Map0.559
2kv5A10.12552.30.968Contact Map0.326
2mc7A10.11031.70.971Contact Map0
3arcK20.13691.40.972Contact Map0.282
4ixqK20.17111.20.973Contact Map0.221

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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