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FLGF - Flagellar basal-body rod protein FlgF
UniProt: P75938 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14270
Length: 251 (246)
Sequences: 2325
Seq/Len: 9.45

FLGF
Paralog alert: 0.88 [within 20: 0.56] - ratio of genomes with paralogs
Cluster includes: FLGE FLGF FLGG
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
88_L 105_I 4.262 1.00
99_Y 166_A 3.693 1.00
80_V 137_I 3.36 1.00
138_A 142_T 3.32 1.00
80_V 201_V 3.182 1.00
108_D 112_Q 3.081 1.00
71_M 205_V 2.941 1.00
71_M 81_A 2.854 1.00
112_Q 128_A 2.802 1.00
174_G 180_R 2.783 1.00
112_Q 119_P 2.751 1.00
66_M 87_W 2.739 1.00
89_A 164_V 2.63 1.00
114_T 118_H 2.594 1.00
90_V 100_T 2.471 1.00
145_A 158_V 2.391 1.00
113_L 120_V 2.287 1.00
172_Q 182_S 2.274 1.00
82_L 163_L 2.252 1.00
137_I 143_I 2.25 1.00
164_V 194_Q 2.246 1.00
85_D 165_K 2.227 1.00
36_A 216_A 2.22 1.00
73_Y 205_V 2.217 1.00
102_N 177_G 2.133 1.00
4_A 237_V 2.108 1.00
32_P 206_L 2.067 1.00
202_M 205_V 2.045 1.00
127_I 159_G 2.023 1.00
37_Q 173_R 1.974 1.00
105_I 120_V 1.873 1.00
172_Q 180_R 1.841 1.00
92_T 98_G 1.809 1.00
91_Q 121_I 1.804 1.00
26_L 213_A 1.803 1.00
181_L 191_P 1.793 1.00
82_L 199_L 1.783 1.00
32_P 102_N 1.771 1.00
239_D 242_G 1.764 1.00
83_Q 202_M 1.736 1.00
72_D 208_G 1.701 1.00
212_N 215_A 1.695 1.00
74_T 79_D 1.671 1.00
80_V 88_L 1.629 1.00
32_P 104_S 1.624 1.00
89_A 97_E 1.604 1.00
18_Q 223_S 1.589 1.00
22_T 223_S 1.57 1.00
22_T 220_M 1.545 1.00
113_L 127_I 1.544 1.00
98_G 174_G 1.536 1.00
10_G 14_Q 1.511 1.00
122_G 162_K 1.504 1.00
92_T 96_S 1.495 1.00
119_P 126_P 1.494 1.00
138_A 144_S 1.479 1.00
19_Q 223_S 1.478 1.00
41_L 45_P 1.471 1.00
80_V 161_L 1.459 1.00
82_L 201_V 1.44 1.00
90_V 114_T 1.428 0.99
121_I 126_P 1.424 0.99
19_Q 220_M 1.422 0.99
114_T 120_V 1.391 0.99
78_L 135_I 1.386 0.99
98_G 178_I 1.386 0.99
64_A 173_R 1.38 0.99
8_A 233_V 1.367 0.99
89_A 121_I 1.364 0.99
78_L 113_L 1.361 0.99
11_A 14_Q 1.352 0.99
21_V 34_F 1.347 0.99
88_L 161_L 1.33 0.99
102_N 115_I 1.324 0.99
34_F 37_Q 1.316 0.99
93_A 118_H 1.305 0.99
70_K 208_G 1.301 0.99
120_V 161_L 1.295 0.99
232_K 235_S 1.286 0.99
90_V 178_I 1.286 0.99
116_Q 176_D 1.28 0.99
142_T 157_P 1.259 0.98
182_S 189_R 1.254 0.98
41_L 44_V 1.238 0.98
9_M 12_A 1.234 0.98
80_V 203_S 1.223 0.98
43_A 54_R 1.21 0.98
166_A 181_L 1.203 0.98
16_L 20_A 1.195 0.98
235_S 238_D 1.189 0.98
161_L 201_V 1.182 0.97
238_D 241_A 1.174 0.97
114_T 178_I 1.165 0.97
15_T 223_S 1.155 0.97
11_A 18_Q 1.155 0.97
36_A 215_A 1.133 0.96
18_Q 219_D 1.133 0.96
90_V 105_I 1.132 0.96
220_M 244_A 1.099 0.96
78_L 107_V 1.093 0.95
21_V 39_N 1.077 0.95
24_S 34_F 1.077 0.95
219_D 222_A 1.077 0.95
36_A 65_D 1.074 0.95
76_R 79_D 1.071 0.95
215_A 219_D 1.069 0.95
15_T 226_R 1.044 0.94
89_A 162_K 1.03 0.93
37_Q 64_A 1.028 0.93
66_M 179_F 1.026 0.93
170_E 190_G 1.026 0.93
87_W 179_F 1.007 0.92
214_V 217_M 1.007 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3a69A10.93631000.152Contact Map0.757
1wlgA20.537899.90.61Contact Map0.81
1oryB10.21917.70.963Contact Map0.571
2gscA50.17531.40.975Contact Map0.328
1wn8A10.08761.40.975Contact Map1
3ziaG20.2391.30.976Contact Map0.349
4dwlA50.17131.20.976Contact Map0.626
2qe7G10.2391.20.976Contact Map0.244
2xokG10.23910.977Contact Map0.599
2kp7A10.22310.90.978Contact Map0.316

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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