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YNJD - Uncharacterized ABC transporter ATP-binding protein YnjD
UniProt: P76909 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14006
Length: 217 (203)
Sequences: 70618
Seq/Len: 347.87

YNJD
Paralog alert: 0.94 [within 20: 0.84] - ratio of genomes with paralogs
Cluster includes: ARTP BTUD CCMA CYSA DDPD DDPF DPPD DPPF FBPC FECE FEPC FHUC FTSE GLNQ GLTL HISP LIVF LIVG LOLD LPTB MALK METN MLAF MODC NIKD NIKE OPPD OPPF PHNC PHNK PHNL POTA POTG PROV PSTB SAPD SAPF SSUB SUFC TAUB THIQ UGPC YADG YBBA YBBL YCJV YDCT YECC YEHX YHDZ YNJD ZNUC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_T 200_D 3.086 1.00
3_C 23_T 3.063 1.00
126_A 129_Q 2.928 1.00
60_E 67_R 2.877 1.00
5_K 60_E 2.831 1.00
28_D 202_S 2.804 1.00
6_N 19_N 2.789 1.00
15_R 18_T 2.721 1.00
77_Q 153_K 2.658 1.00
119_E 124_E 2.657 1.00
3_C 62_W 2.572 1.00
25_D 28_D 2.494 1.00
30_V 204_L 2.359 1.00
8_S 19_N 2.229 1.00
9_L 46_W 2.177 1.00
4_V 7_V 2.165 1.00
64_N 153_K 2.112 1.00
10_R 15_R 2.109 1.00
8_S 15_R 2.095 1.00
8_S 58_T 2.071 1.00
93_V 134_L 2.01 1.00
115_N 127_F 2.002 1.00
118_L 127_F 1.972 1.00
5_K 62_W 1.946 1.00
113_A 151_Q 1.938 1.00
94_G 128_H 1.859 1.00
94_G 127_F 1.795 1.00
151_Q 185_I 1.767 1.00
120_R 178_S 1.726 1.00
26_K 153_K 1.711 1.00
178_S 182_A 1.709 1.00
94_G 115_N 1.708 1.00
6_N 21_N 1.676 1.00
28_D 201_S 1.651 1.00
11_L 16_L 1.602 1.00
116_D 120_R 1.599 1.00
9_L 54_Q 1.593 1.00
94_G 114_V 1.591 1.00
94_G 98_L 1.524 1.00
129_Q 133_T 1.497 1.00
44_F 190_V 1.485 1.00
83_Q 136_G 1.474 1.00
120_R 183_L 1.468 1.00
62_W 67_R 1.444 1.00
10_R 54_Q 1.443 1.00
9_L 51_L 1.436 1.00
24_V 30_V 1.416 1.00
4_V 47_M 1.357 0.99
17_L 46_W 1.349 0.99
5_K 23_T 1.338 0.99
106_K 109_A 1.337 0.99
113_A 116_D 1.337 0.99
157_L 176_V 1.328 0.99
44_F 156_L 1.327 0.99
8_S 18_T 1.319 0.99
124_E 127_F 1.313 0.99
98_L 114_V 1.302 0.99
46_W 53_E 1.289 0.99
120_R 182_A 1.284 0.99
22_F 204_L 1.273 0.99
115_N 119_E 1.254 0.99
4_V 22_F 1.246 0.98
7_V 53_E 1.246 0.98
96_N 146_R 1.244 0.98
112_N 116_D 1.241 0.98
97_L 149_L 1.231 0.98
92_S 95_Q 1.206 0.98
180_V 201_S 1.198 0.98
5_K 21_N 1.195 0.98
126_A 138_Q 1.19 0.98
115_N 124_E 1.189 0.98
111_R 115_N 1.189 0.98
64_N 77_Q 1.188 0.98
93_V 142_V 1.174 0.98
45_S 51_L 1.163 0.97
191_T 197_V 1.15 0.97
47_M 188_V 1.144 0.97
180_V 187_V 1.143 0.97
94_G 111_R 1.142 0.97
4_V 43_L 1.139 0.97
29_I 187_V 1.122 0.97
173_R 196_D 1.117 0.96
175_W 178_S 1.11 0.96
169_R 196_D 1.1 0.96
9_L 42_T 1.079 0.95
29_I 180_V 1.068 0.95
11_L 42_T 1.064 0.95
121_S 145_L 1.061 0.95
117_A 149_L 1.06 0.95
67_R 70_I 1.055 0.95
153_K 185_I 1.051 0.94
26_K 64_N 1.048 0.94
81_L 144_L 1.047 0.94
48_I 80_I 1.045 0.94
122_G 171_N 1.042 0.94
118_L 123_L 1.04 0.94
98_L 110_R 1.032 0.94
25_D 202_S 1.03 0.94
20_V 43_L 1.025 0.93
30_V 202_S 1.018 0.93
81_L 157_L 1.017 0.93
32_L 43_L 1.014 0.93
1_M 64_N 1.013 0.93
116_D 119_E 1.011 0.93
10_R 16_L 1.01 0.93
134_L 142_V 1.009 0.93
97_L 118_L 1.008 0.93
130_D 133_T 1.003 0.93
117_A 145_L 1.002 0.92
48_I 156_L 1.002 0.92
169_R 193_D 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2it1A20.9862100-0.017Contact Map0.861
1v43A10.9862100-0.016Contact Map0.812
2yyzA10.9862100-0.013Contact Map0.812
1z47A20.9862100-0.012Contact Map0.828
1g29120.9862100-0.011Contact Map0.896
1oxxK10.9862100-0.011Contact Map0.806
3rlfA20.9862100-0.007Contact Map0.853
3fvqA20.9862100-0.007Contact Map0.764
3tuiC40.9862100-0.005Contact Map0.878
3d31A20.97241000.001Contact Map0.816

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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